Results 181 to 190 of about 41,079 (213)

The cGAS–STING pathway as a therapeutic target in inflammatory diseases

Nature Reviews Immunology, 2021
Alexiane Decout, Andrea Ablasser
exaly  

IEEE CGA

IEEE Security & Privacy, 2022
openaire   +1 more source

cGAS–STING drives ageing-related inflammation and neurodegeneration

Nature, 2023
Muhammet Gulen, Marius Schwabenland
exaly  

CGAS

2007
Kwangmin Choi, Youngik Yang, Sun Kim
openaire   +1 more source

CGA filler

Computer, 2022
openaire   +1 more source

cGAS–STING drives the IL-6-dependent survival of chromosomally instable cancers

Nature, 2022
Michael Schubert, Marta Requesens Rueda, Maurits Roorda   +2 more
exaly  

cGAS senses translation stress

Nature Cell Biology, 2021
openaire   +2 more sources

Keeping cGAS in check: SPSB3 promotes nuclear cGAS degradation for maintaining immune homeostasis

Molecular Cell
In a recent publication in Nature, Xu et al.1 discovered a role of CRL5-SPSB3 ubiquitin ligase in promoting ubiquitination and degradation of nuclear cGAS, which prevents aberrant cGAS activation by genomic DNA and contributes to the maintenance of immune homeostasis.
openaire   +2 more sources

Molecular mechanisms and cellular functions of cGAS–STING signalling

Nature Reviews Molecular Cell Biology, 2020
Karl-Peter Hopfner, Veit Hornung
exaly  

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

Cancer Cell, 2021
Junhong Guan, Changzheng Lu, Huiming Lu
exaly