Results 91 to 100 of about 148,798 (282)
Proceedings of the National Academy of Sciences of the United States of America, 1994 Nitric oxide (NO)-induced relaxation is associated with increased levels of cGMP in vascular smooth muscle cells. However, the mechanism by which cGMP causes relaxation is unknown.
S. Archer +5 more
semanticscholar +1 more source
cGMP in ozone and NO dependent responses [PDF]
Plant Signaling & Behavior, 2008 We have recently reported that ozone (O(3)) can inhibit mitochondrial respiration and induce activation of the alternative oxidase (AOX) pathway and in particular AOX1a in tobacco. While O(3) causes mitochondrial H(2)O(2), early leaf nitric oxide (NO) as well as transient ethylene (ET) accumulation, the levels of jasmonic acid and 12-oxo-phytodienoic ...
EDERLI, Luisa +6 more
openaire +4 more sources
The role of cGMP and PKG in cardioprotection [PDF]
BMC Pharmacology, 2009 Interrupting blood flow to a heart (ischemia) for several minutes followed by several minutes of restored flow renders it very resistant to cell death from a subsequent much more prolonged ischemic episode. This phenomena, termed ischemic preconditioning, is the result of a complex signal transduction pathway which ultimately prevents formation of ...
James M. Downey +2 more
openaire +2 more sources
Orphanet Journal of Rare Diseases, 2019 In phenylketonuria, casein glycomacropeptide (CGMP) requires modification with the addition of some essential and semi essential amino acids to ensure suitability as a protein substitute.
A. Daly +9 more
doaj +1 more source
PAK-in' Up cGMP for the Move [PDF]
Cell, 2007 Although guanylyl cyclases have been implicated in cell migration, how they are activated to promote cell motility is unknown. In this issue, report direct communication between guanylyl cyclases and the Rac-p21-activated kinase (PAK) signaling pathway--which is essential for cell migration--to promote cell motility, through allosteric activation of ...
openaire +3 more sources
Tonic and phasic nitric oxide signals in hippocampal long-term potentiation [PDF]
, 2006 Nitric oxide ( NO) participates in long-term potentiation (LTP) and other forms of synaptic plasticity in many different brain areas but where it comes from and how it acts remain controversial.
Garthwaite, J, Hopper, RA
core +1 more source
Scientific ReportsRecent clinical trials of drugs enhancing cyclic guanosine monophosphate (cGMP) signaling for cardiovascular diseases have renewed interest in cGMP biology within the kidney.
Nelli Rutkowski +7 more
doaj +1 more source
Phosphodiesterase 5 attenuates the vasodilatory response in renovascular hypertension.
PLoS ONE, 2013 NO/cGMP signaling plays an important role in vascular relaxation and regulation of blood pressure. The key enzyme in the cascade, the NO-stimulated cGMP-forming guanylyl cyclase exists in two enzymatically indistinguishable isoforms (NO-GC1, NO-GC2) with
Johannes Stegbauer +8 more
doaj +1 more source
Cell Transplantation, 2020 Standardized islet characterization assays that can provide results in a timely manner are essential for successful islet cell transplantation. A critical component of islet cell quality is β-cell function, and perifusion-based assessments of dynamic ...
Oscar Alcazar +4 more
doaj +1 more source
The role of cGMP as a mediator of lipolysis in bovine oocytes and its effects on embryo development and cryopreservation. [PDF]
PLoS ONE, 2018 This study aimed to determine the influence of cyclic guanosine 3'5'-monophosphate (cGMP) and cGMP-dependent kinase (PKG) during in vitro maturation (IVM) on lipolysis-related parameters in bovine cumulus-oocyte complexes (COCs), and on embryo ...
Kátia R L Schwarz +6 more
doaj +1 more source