Results 21 to 30 of about 28,625 (273)
Steroidal chalcones and derivatives: a review
Arkivoc, 2021 It was observed that the presence of heterocycles to steroids often leads to a change in their physiological activity and the appearance of new interesting biological precursors. Recent developments in the syntheses of steroidal chalcones and their derivatives are described herein. The biological activities of those steroidal derivatives for which data
Ibrahim-Ouali, Malika, Dumur, Frédéric
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Nature Communications, 2020 Chalcone synthase is the first committed enzyme in the plant flavonoid biosynthesis pathway, yet shows low product specificity in vitro. Here Waki et al.
Toshiyuki Waki +20 more
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2-Hydroxychalcone as a Potent Compound and Photosensitizer Against Dermatophyte Biofilms
Frontiers in Cellular and Infection Microbiology, 2021 Dermatophytes, fungi that cause dermatophytosis, can invade keratinized tissues in humans and animals. The biofilm-forming ability of these fungi was described recently, and it may be correlated with the long treatment period and common recurrences of ...
Níura Madalena Bila +9 more
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Phthalocyanine-chalcone conjugates
Journal of Porphyrins and Phthalocyanines, 2016 A phthalocyanine-chalcone conjugate was previously reported to retain the full photodynamic activity of the phthalocyanine and a slightly lowered antivascular effect of the chalcone. Assuming that it was due to an insufficient release of the chalcone, we described here several grafting modes applied to the preparation of phthalocyanine-chalcone ...
Khalil Bennis +22 more
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Synthesis of Chalcones with Anticancer Activities [PDF]
Molecules, 2012 Several chalcones were synthesized and their in vitro cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3, human adenocarcinoma cell line HT-29 (colorectal cancer) and human normal liver cell line WRL-68 was evaluated. Most of
Suvitha Syam +3 more
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A new member of the chalcone synthase (CHS) family in sugarcane
Genetics and Molecular Biology, 2001 Sequences from the sugarcane expressed sequence tag (SUCEST) database were analyzed based on their identities to genes encoding chalcone-synthase-like enzymes.
Miriam G.G. Contessotto +3 more
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Reaction of chalcones with phenylhydrazine [PDF]
Pharmaceutical Chemistry Journal, 1976 AbstractChalkone (I) reagieren mit Phenylhydrazin (II) zu Pyrazolinen (III) (Ausbeute 38 ‐ 72%).
Yakovenko V.I. +3 more
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Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
Allergology International, 2010 Background: : Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes.
Chiaki Iwamura +5 more
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Synthesis and Biological Evaluation of Amino Chalcone Derivatives as Antiproliferative Agents
Molecules, 2020 Chalcone is a common scaffold found in many biologically active compounds. The chalcone scaffold was also frequently utilized to design novel anticancer agents with potent biological efficacy.
Chao-Fan Lu +14 more
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Effects of Cholesterol on the Breast Cancer Resistance Protein: Studies through the Synthesis and Biological Evaluation of Chemical Tools. [PDF]
ChemMedChemThis study explores the role of cholesterol in the regulation of the efflux pump ABCG2. Substrates and inhibitors of ABCG2, cholesterol linked to fluorescents probes were synthesized and tested to investigate the influence of cholesterol on ABCG2 inhibition and to track cholesterol trafficking on cells.
Fatima Zattoni I +6 more
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