Results 31 to 40 of about 74,636 (287)

2-Hydroxychalcone as a Potent Compound and Photosensitizer Against Dermatophyte Biofilms

Frontiers in Cellular and Infection Microbiology, 2021
Dermatophytes, fungi that cause dermatophytosis, can invade keratinized tissues in humans and animals. The biofilm-forming ability of these fungi was described recently, and it may be correlated with the long treatment period and common recurrences of ...
Níura Madalena Bila, Níura Madalena Bila, Caroline Barcelos Costa-Orlandi, Carolina Orlando Vaso, Jean Lucas Carvalho Bonatti, Letícia Ribeiro de Assis, Luís Octavio Regasini, Carla Raquel Fontana, Ana Marisa Fusco-Almeida, Maria José Soares Mendes-Giannini   +9 more
doaj   +1 more source

Design and synthesis of new inhibitors of p53–MDM2 interaction with a chalcone scaffold [PDF]

, 2019
The virtual screening of a library of chalcone derivatives led us to the identification of potential new MDM2 ligands. The chalcones with the best docking scores obeying the Lipinski rule of five were subsequently prepared by base-catalyzed aldol ...
Cidade, Honorina, Gomes, Sara, Helena Vasconcelos, M., Lima, Raquel T., Maciel, Claudia, Palmeira, Andreia, Pereira, Daniela, Pinto, Madalena, Raimundo, Liliana, Saraiva, Lucília, Seca, Hugo, Soares, Joana, Sousa, Emília   +12 more
core   +3 more sources

Study of Michael addition on chalcones and or chalcone analogues

Journal of Saudi Chemical Society, 2012
AbstractMichael addition reaction of 1,3-diphenyl-propenone 1a, e, and f with o-amino thiophenol in the presence of indium trichloride gave the benzothiazine derivatives 2a–c. Condensation of the compound 1a, e with o-phenylene diamine in triethylamine gave the benzodiazepine derivatives 3a–b.
Makarem M.S. Karah, Amal S.A. Bougasim, Nabila A. Al-Jaber   +2 more
openaire   +2 more sources

Synthesis of Chalcone Derivatives and Their in vitro Anticancer Test Against Breast (T47D) and Colon (WiDr) Cancer Cell Line

Indonesian Journal of Chemistry, 2018
The synthesis of chalcone derivatives as target compounds and anticancer test against breast (T47D) and colon (WiDr) cell line had been performed.
Chairil Anwar, Yogo Dwi Prasetyo, Sabirin Matsjeh, Winarto Haryadi, Eti Nurwening Sholikhah, Nendrowati Nendrowati   +5 more
doaj   +1 more source

The Benefits of Chalcone and Its Derivatives as Antibacterial Agents: A Review

BIO Web of Conferences, 2020
Chalcone is a secondary metabolite compound found in plants. Chalcones contain two aryl rings, namely ring A and B which connected to the α,β unsaturated ketones.
Mustikasari Kamilia, Trisno Santoso Uripto   +1 more
doaj   +1 more source

Three AP2/ERF family members modulate flavonoid synthesis by regulating type IV chalcone isomerase in citrus

Plant Biotechnology Journal, 2020
Summary Flavanones and flavones are excellent source of bioactive compounds but the molecular basis of their highly efficient production remains elusive.
Chenning Zhao, Xiaojuan Liu, Qin Gong, Jinping Cao, Wanxia Shen, Xue‐ren Yin, D. Grierson, Bo Zhang, Changjie Xu, Xian Li, Kun-song Chen, Chongde Sun   +11 more
semanticscholar   +1 more source

Recent Advances in bis-Chalcone-Based Photoinitiators of Polymerization: From Mechanistic Investigations to Applications

Molecules, 2021
Over the past several decades, photopolymerization has become an active research field, and the ongoing efforts to develop new photoinitiating systems are supported by the different applications in which this polymerization technique is involved ...
N. Giacoletto, F. Dumur
semanticscholar   +1 more source

Phytoestrogens [PDF]

, 2004
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H, Alekel DL, Bhathena SJ, Bielenberg J, Biendl M, Boller B, Dai Q, Day JK, de Kleijn MJJ, den Tonkelaar I, denTonkelaar I, Dewick PM, Ebisawa H, Fritz WA, Guo TL, Hodgson JM, Horn-Ross PL, ILDIS, Kim CS, Lamartiniere CA, Maggiolini M, Maskarinec G, McCann SE, Mentor MR, MerzDemlow BE, Newbold RR, Pan W, Peluso MR, Richard A. Dixon, Seested S, Setchell KDR, Setchell KDR, Setchell KDR, Slavin JL, Stevens JF, Whitten PL, Yanagihara K, Zhang Y   +37 more
core   +1 more source

Exploring the 2′-Hydroxy-Chalcone Framework for the Development of Dual Antioxidant and Soybean Lipoxygenase Inhibitory Agents

Molecules, 2021
2′-hydroxy-chalcones are naturally occurring compounds with a wide array of bioactivity. In an effort to delineate the structural features that favor antioxidant and lipoxygenase (LOX) inhibitory activity, the design, synthesis, and bioactivity profile ...
Ioanna Kostopoulou, Andromachi Tzani, Nestor-Ioannis Polyzos, Maria-Anna Karadendrou, E. Kritsi, E. Pontiki, Thalia Liargkova, D. Hadjipavlou-Litina, P. Zoumpoulakis, A. Detsi   +9 more
semanticscholar   +1 more source

Synthesis of Chalcones with Anticancer Activities [PDF]

Molecules, 2012
Several chalcones were synthesized and their in vitro cytotoxicity against various human cell lines, including human breast adenocarcinoma cell line MCF-7, human lung adenocarcinoma cell line A549, human prostate cancer cell line PC3, human adenocarcinoma cell line HT-29 (colorectal cancer) and human normal liver cell line WRL-68 was evaluated. Most of
Suvitha Syam, Siddig Ibrahim Abdelwahab, Mohammed Ali Al-Mamary, Syam Mohan   +3 more
openaire   +4 more sources