Chempublish Journal, 2023 Molecular docking study of 6 chalcone analogues with protein target from the crystallographic structure modeling of Bcl-2 protein with PDB code 2W3L was carried out using computational media using the Molecular Operating Environment (MOE) program.
Neni Frimayanti +2 more
doaj +1 more source
Angelica keiskei, an emerging medicinal herb with various bioactive constituents and biological activities. [PDF]
, 2017 Angelica keiskei (Miq.) Koidz. (Umbelliferae) has traditionally been used to treat dysuria, dyschezia, and dysgalactia as well as to restore vitality. Recently, the aerial parts of A. keiskei have been consumed as a health food.
Jafari, Mahtab +3 more
core +1 more source
Chalcone: A Privileged Structure in Medicinal Chemistry.
Chemical Reviews, 2017 Privileged structures have been widely used as an effective template in medicinal chemistry for drug discovery. Chalcone is a common simple scaffold found in many naturally occurring compounds.
Chunlin Zhuang +5 more
semanticscholar +1 more source
New chalcone derivatives as effective against SARS‐CoV‐2 agent
International journal of clinical practice, 2021 Flavonoids and related compounds, such as quercetin‐based antiviral drug Gene‐Eden‐VIR/Novirin, inhibit the protease of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
N. Duran +9 more
semanticscholar +1 more source
A new member of the chalcone synthase (CHS) family in sugarcane
Genetics and Molecular Biology, 2001 Sequences from the sugarcane expressed sequence tag (SUCEST) database were analyzed based on their identities to genes encoding chalcone-synthase-like enzymes.
Miriam G.G. Contessotto +3 more
doaj +1 more source
Synthesis and Biological Evaluation of Amino Chalcone Derivatives as Antiproliferative Agents
Molecules, 2020 Chalcone is a common scaffold found in many biologically active compounds. The chalcone scaffold was also frequently utilized to design novel anticancer agents with potent biological efficacy.
Chao-Fan Lu +14 more
doaj +1 more source
Intra- and inter-metabolite correlation spectroscopy of tomato metabolomics data obtained by liquid chromatography-mass spectrometry and nuclear magnetic resonance [PDF]
, 2008 Nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LCMS) are frequently used as technological platforms for metabolomics applications.
Bino, R.J. +4 more
core +2 more sources
Reaction of chalcones with phenylhydrazine [PDF]
Pharmaceutical Chemistry Journal, 1976 AbstractChalkone (I) reagieren mit Phenylhydrazin (II) zu Pyrazolinen (III) (Ausbeute 38 ‐ 72%).
Yakovenko V.I. +3 more
openaire +4 more sources
Naringenin Chalcone Suppresses Allergic Asthma by Inhibiting the Type-2 Function of CD4 T Cells
Allergology International, 2010 Background: : Some polyphenols possess anti-allergic activities. Naringenin chalcone is one of the polyphenols that is present in the skin of red tomatoes.
Chiaki Iwamura +5 more
doaj +1 more source
Natural Product Rottlerin Derivatives Targeting Quorum Sensing
Molecules, 2021 Rottlerin is a natural product consisting of chalcone and flavonoid scaffolds, both of which have previously shown quorum sensing (QS) inhibition in various bacteria.
Dittu Suresh +6 more
doaj +1 more source