Chalcone derivatives' interaction with human serum albumin and cyclooxygenase-2. [PDF]
Karthikeyan S +9 more
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In silico screening of chalcone derivatives as promising EGFR-TK inhibitors for the clinical treatment of cancer. [PDF]
Mathpal S +6 more
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Isomerism and Polymerphism of Chalcone Derivatives.
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Coumarin-chalcone derivatives as dual NLRP1 and NLRP3 inflammasome inhibitors targeting oxidative stress and inflammation in neurotoxin-induced HMC3 and BE(2)-M17 cell models of Parkinson's disease. [PDF]
Lin TH +8 more
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Synthesis, Characterization, Antioxidant, and Anticancer Activity against Colon Cancer Cells of Some Cinnamaldehyde-Based Chalcone Derivatives. [PDF]
El-Atawy MA +7 more
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Comprehensive Study of Chalcone Derivatives
International Journal of Newgen Research in Pharmacy & Healthcare, 2023Chalcones are flavonoid molecules that exist naturally and are essentially plant substances. These are the chemical compounds that have demonstrated a variety of intriguing biological actions with therapeutic potential against a variety of ailments. Anthranilic acid and orthophenylene diamine combine to produce benzimidazole.
Dudhe A. R. +4 more
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Structural study on chalcone derivatives
Synthetic Metals, 1994Abstract Crystal structures of several SHG-active chalcone derivatives were determined by X-ray analysis. The phase-matching direction of a 1-(3-thienyl)-3-(4-chlorophenyl)-2-propen-1-one crystal is discussed by relating to its molecular packing in the crystal.
T. Uchida, K. Kozawa, Y. Kimura, Y. Goto
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Anticancer activities of novel chalcone and bis-chalcone derivatives
Bioorganic & Medicinal Chemistry, 2006A series of novel chalcones and bis-chalcones containing boronic acid moieties has been synthesized and evaluated for antitumor activity against the human breast cancer MDA-MB-231 (estrogen receptor-negative) and MCF7 (estrogen receptor-positive) cell lines and against two normal breast epithelial cell lines, MCF-10A and MCF-12A.
Aneta, Modzelewska +5 more
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Stereoselectivity of chalcone isomerase with chalcone derivatives: a computational study
Journal of Molecular Modeling, 2013Chalcone isomerase (CHI) catalyzes the intramolecular cyclization of chalcones into flavonoids. The activity of CHI is essential for the biosynthesis of flavonoids precursors of floral pigments and phenylpropanoid plant defense compounds. In the present study, we explored the detailed binding structures and binding free energies for two different ...
Yuan, Yao, Hui, Zhang, Ze-Sheng, Li
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Chalcone derivatives from Polygonum lapathifolium
Phytochemistry, 1988Abstract The investigation of Polygonum lapathifolium L. afforded, in addition to 2′-hydroxy-4′,6′-dimethoxychalcone, three new derivatives. The structures were elucidated by high field 1 H NMR techniques.
Maniruddin Ahmed +2 more
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