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QUANTUM-CHEMICAL CALCULATION OF CHALCON DERIVATIVES

SAKHAROV READINGS 2022: ENVIRONMENTAL PROBLEMS OF THE XXI CENTURY Part 2, 2022
The paper presents the data of semi-empirical and theoretical calculations of molecules in the medium of the solvent, their absorption spectrum and the optimized structure with the value of the total energy of the system.
M. A. Atroshko   +5 more
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OESTROGENIC AND ANTIFERTILITY EFFECTS OF CHALCONE DERIVATIVES

Acta Endocrinologica, 1973
ABSTRACT Three newly synthesized non-steroidal derivatives of chalcone (benzalacetophenone), viz., 2′-chloro-4:4′-difluorochalcone (CH-4), 2′-chloro-3:4-methylenedioxy-4′-fluorochalcone (CH-6) and 2′-hydroxy-3:4-methylenedioxy-4′-fluorochalcone (CH-8) were evaluated for their oestrogenicity in the mouse and were found to possess a statistically
D, Jacob, D K, Kaul
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Flavanone and Chalcone Derivatives from Cryptocarya kurzii

Journal of Natural Products, 1993
Four complex flavanones, kurziflavolactones A [2], B [3], C [4], and D [5] and a complex chalcone 6 with an unprecedented carbon side chain on the flavanone or chalcone A ring have been isolated from a Malaysian plant, Cryptocarya kurzii (Lauraceae).
X, Fu   +6 more
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Phenylsulfonyl derivatives of chalcones derived from 5-nitrofuran

Collection of Czechoslovak Chemical Communications, 1983
1-(5-Nitro-2-furoyl)-1-phenylsulfonyl-2-(4-X-phenyl)ethylenes II were synthesized by condensation of phenyl-2-(5-nitro-2-furyl)-2-oxoethyl sulfone (I) with 4-substituted benzaldehydes (X = H, CH3, CH3O, N(CH3)2, F, Cl, NO2, CN) in tetrahydrofuran or dioxane under catalysis of titanium-IV chloride and pyridine. As evidenced by spectral data (1H NMR, IR,
Adolf Jurášek   +2 more
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Antifungal action of the oxathiolone‐fused chalcone derivative

Mycoses, 2011
SummaryAMG‐148, an oxathiolone‐fused chalcone derivative, exhibited in vitro antifungal activity against several strains of human pathogenic yeast, with minimum inhibitory concentration values within the range of 1–16 μg ml−1 and a fungicidal effect was observed at higher concentrations.
Izabela, Łącka   +4 more
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Solvatochromic hydrazone anions derived from chalcones

Dyes and Pigments, 2008
Abstract The preparation and solvatochromism of anions derived from the 2,4-dinitrophenylhydrazones of 1,3-diphenylpropenone, 1-phenyl-3-(4-nitrophenyl)propenone and 1-phenyl-3-(2-thienyl)propenone are described and their behaviour was interpreted in terms of theoretical calculations of their internal charge-transfer transitions.
Daniela Millán   +2 more
openaire   +1 more source

Novel diphenysulphapyrimidine acetates derived from chalcones

Journal of Heterocyclic Chemistry, 1989
AbstractCyclocondensation of sulphaguanidine acetate with chalcones in dimethylsulphoxide at 110° gave 4,6‐diphenylsulphapyrimidine acetates.
C. O. Usifoh   +4 more
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Dimeric chalcone derivatives from Mallotus philippensis

Phytochemistry, 1998
Two new chalcone derivatives with a unique ring system caused by dimerization between a dimethylchromene ring and a phenoxyl group, were isolated from kamala (Mallotus philippensis). The structures were determined by spectral analysis.
Toshiyuki Tanaka   +4 more
openaire   +1 more source

Synthesis and antimalarial activity of sulfonamide chalcone derivatives

Il Farmaco, 2005
A series of sulfonamide chalcone derivatives were synthesized and investigated for their abilities to inhibit beta-hematin formation in vitro and their activity against cultured Plasmodium falciparum parasites. Inhibition of beta-hematin formation was minimal in the aromatic ring of the chalcone moiety as it appeared for compounds 4b, 4d-f, and ...
José N, Domínguez   +5 more
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Synthesis and biological activities of fluorinated chalcone derivatives

Bioorganic & Medicinal Chemistry, 2002
We have designed and synthesized new 5-lipoxygenase inhibitors, fluorinated 3,4-dihydroxychalcones, and evaluated their biological activities with respect to antiperoxidation activity and in vitro antitumor activities. All fluorinated chalcones tested showed 5-lipoxygenase inhibition on rat basophilic leukemia-1 (RBL-1) cells and inhibitory action on ...
Chika, Nakamura   +9 more
openaire   +2 more sources

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