Results 131 to 140 of about 53,724 (334)

Synthesis and study of polyhydroxylated phenol derivatives with potential cosmetic and phytoiatric applications [PDF]

, 2013
Tyrosinase (polyphenol oxidase, E.C. 1.14.18.1) and laccase (phenol oxidase, E.C. 1.10.3.2) are multifunctional copper-containing enzymes, that are keys in melanin biosynthesis, melanisation in animals and browning in plants.
Dallocchio, Roberto, Delogu, Giovanna, Dessì, Alessandro, Dettori, Maria Antonietta, Fabbri, Davide, Fois, Xenia, Pantaleoni, Roberto Antonio, Rocchitta, Gaia Giovanna Maria, Serra, Pier Andrea   +8 more
core  

Exploring absorption indices for a variety of polyphenols through Caco‐2 cell model: insights from permeability studies and principal component analysis

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Phytochemicals have long been utilized as active ingredients in the developing of novel functional foods or drugs due to their diverse biological and pharmacological effects. Many studies have demonstrated that polyphenols exhibit low absorption rates and are extensively metabolized into various metabolites, resulting in ...
Dong‐Ho Lee, Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Chau Hoang Bao Nguyen, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +7 more
wiley   +1 more source

Stenotrophomonas maltophilia: A Gram-Negative Bacterium Useful for Transformations of Flavanone and Chalcone

Molecules, 2017
A group of flavones, isoflavones, flavanones, and chalcones was subjected to small-scale biotransformation studies with the Gram-negative Stenotrophomonas maltophilia KB2 strain in order to evaluate the capability of this strain to transform flavonoid ...
Edyta Kostrzewa-Susłow, Monika Dymarska, Urszula Guzik, Danuta Wojcieszyńska, Tomasz Janeczko   +4 more
doaj   +1 more source

The Antiviral Activity of Polyphenols

Molecular Nutrition &Food Research, EarlyView.
Polyphenols demonstrate remarkable antiviral properties by effectively disrupting multiple biochemical processes essential for viral replication. ABSTRACT Polyphenols are secondary metabolites produced by a large variety of plants. These compounds that comprise the class of phenolic acids, stilbenes, lignans, coumarins, flavonoids, and tannins have a ...
Markus Burkard, Alban Piotrowsky, Christian Leischner, Katja Detert, Sascha Venturelli, Luigi Marongiu   +5 more
wiley   +1 more source

Synthesis and Preliminary Evaluation of Several Chalcone Derivatives as Sunscreen Compounds

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2019
Four chalcone derivatives were synthesized and pre-evaluated as broad-spectrum UV protector. Chalcones 1-4 showed a wide range of UV absorbance values and moderate molar absorptivity values. Chalcones 3 and 4 showed better photostability than chalcones 1
Jumina Jumina, Rizky Woro Styaningrum, Dwi Siswanta, Sugeng Triono, Yoga Priastomo, Harizal Harizal, Eti Nurwening Sholikhah, Abdul Karim Zulkarnain   +7 more
doaj   +1 more source

Halo-Substituted Chalcones and Azachalcones-Inhibited, Lipopolysaccharited-Stimulated, Pro-Inflammatory Responses through the TLR4-Mediated Pathway

Molecules, 2018
A series of B-ring, halo-substituted chalcones and azachalcones were synthesized to evaluate and compare their anti-inflammatory activity. Mouse BALB/c macrophage RAW 264.7 were pre-treated with 10 μg/mL of each compound for one hour before induction of ...
Tzenge-Lien Shih, Ming-Hwa Liu, Chia-Wai Li, Chia-Feng Kuo   +3 more
doaj   +1 more source

Chalcones and Flavanones Bearing Hydroxyl and/or Methoxyl Groups: Synthesis and Biological Assessments

Applied Sciences, 2019
Chalcones and flavanones are isomeric structures and also classes of natural products, belonging to the flavonoid family. Moreover, their wide range of biological activities makes them key scaffolds for the synthesis of new and more efficient drugs.
G. Rosa, A. Seca, M. Barreto, Artur M. S. Silva, D. Pinto   +4 more
semanticscholar   +1 more source

Experimental and quantum chemical studies of a novel synthetic prenylated chalcone [PDF]

, 2013
BACKGROUND: Chalcones are ubiquitous natural compounds with a wide variety of reported biological activities, including antitumoral, antiviral and antimicrobial effects.
Alejandro A Camacho-Dávila, Daniel Glossman-Mitnik, Guadalupe V Nevárez-Moorillón, José C Espinoza-Hicks, Luz M Rodríguez-Valdez, Norma R Flores-Holguín   +5 more
core   +1 more source

A Systematic Review of Synthetic and Anticancer and Antimicrobial Activity of Quinazoline/Quinazolin‐4‐one Analogues

ChemistryOpen, EarlyView.
Quinazoline represents an important class of heterocycles with diverse medicinal and pharmacological significance. This review systematically examines scholarly efforts toward understanding different synthetic pathways emphasizing the role of metal and non‐metal catalysts including some miscellaneous reagents employed in the synthesis of quinazoline ...
Neha Manhas, Gobind Kumar, Sanjeev Dhawan, Talent Makhanya, Parvesh Singh   +4 more
wiley   +1 more source

Optimized one-pot synthesis of monoarylidene and unsymmetrical diarylidene cycloalkanones [PDF]

, 2016
Ionic liquid dimethylammonium dimethylcarbamate (DIMCARB) catalyzed reaction for the synthesis of monoarylidene and unsymmetrical diarylidene cycloalkanones has been developed. Catalytic amount of DIMCARB was used in green solvent (water and ethanol) for
Din, Zia Ud, Rodrigues-Filho, Edson
core   +1 more source