Results 111 to 120 of about 1,561,447 (191)

Chaperone-mediated autophagy regulates the metastatic state of mesenchymal tumors

EMBO Molecular Medicine
Tumors often recapitulate programs to acquire invasive and dissemination abilities, during which pro-metastatic proteins are distinctively stabilized in cancer cells to drive further progression.
Xun Zhou, Eva Berenger, Yong Shi, Vera Shirokova, Elena Kochetkova, Tina Becirovic, Boxi Zhang, Vitaliy O Kaminskyy, Yashar Esmaeilian, Kayoko Hosaka, Cecilia Lindskog, Per Hydbring, Simon Ekman, Yihai Cao, Maria Genander, Marcin Iwanicki, Erik Norberg, Helin Vakifahmetoglu-Norberg   +17 more
doaj   +1 more source

KFERQ-selective protein autophagy in Caenorhabditis elegans depends on LMP-1.

PLoS ONE
Mammalian cells exhibit three autophagy mechanisms: macroautophagy, microautophagy (MIA), and chaperone-mediated autophagy (CMA), each employing unique mechanisms for transporting cellular material to the lysosome for degradation.
María Gallardo-Campos, Alicia N Minniti, Juan Hormazabal, Gonzalo Núñez, Carlos F Lagos, Tomás Perez-Acle, Rebeca Aldunate, Iván E Alfaro   +7 more
doaj   +1 more source

PRRSV N protein antagonizes host antiviral immune responses by upregulating HSPA1B to induce autophagic degradation of Fos-related antigen 1

mBio
Porcine reproductive and respiratory syndrome virus (PRRSV) infection often causes severe immunosuppression in pigs. However, the mechanisms by which PRRSV antagonizes host antiviral immune responses remain incompletely understood.
Xiao Liu, Jianwu Zhang, Xiaoyang Yan, Yinan Meng, Haozhe Wang, Fang Lv, Bo Peng, Zifang Zheng, Yang Li, Yingtong Feng, Lele Xu, Shuqi Xiao   +11 more
doaj   +1 more source

Chaperone/usher machinery [PDF]

, 2012
Many virulence organelles of Gram-negative bacterial pathogens are assembled via the periplasmic chaperone/usher (CU) pathway. The assembly process is a complex task, involving secretion of organelle subunits via the two membranes and periplasm, subunit ...
Yu, Xiaodi
core  

Determining new functions of Adenovirus VA-RNAI and its use in cancer therapy [PDF]

, 2009
PhDVirus-Associated RNA I (VA-RNAI; VAI) of adenovirus is a nontranslated RNA molecule known to interact with several dsRNA-binding molecules in host cells.
Binny, Christopher Jonathan
core  

Chaperone-Mediated Autophagy Regulates Hypoxic Pathology in Cardiomyocytes

Autophagy Reports, 2023
Rajeshwary Ghosh, J. Scott Pattison
doaj   +1 more source

Chaperone-mediated autophagy [PDF]

Science-Business eXchange, 2011
openaire   +1 more source

Chaperone-mediated autophagy is a tumor-suppressive mechanism in hepatocellular carcinoma. [PDF]

Cell Rep
Patel K, Zapateria B, Ledet AJ, Hazaveh SS, Gjergjova F, Diaz A, Sidoli S, Lujambio A, Cuervo AM, Macian F, Arias E.   +10 more
europepmc   +1 more source

The pleiotropic impact of chaperone-mediated autophagy on skeletal muscle integrity. [PDF]

Autophagy
Dialynaki D, Klionsky DJ.
europepmc   +1 more source

Starvation-induced HSC70 O-GlcNAcylation activates chaperone-mediated autophagy. [PDF]

J Biol Chem
Xu N, Wang X, Zhang J, Zhao J, Yan S, Zhou W, Chi W, Li J.   +7 more
europepmc   +1 more source