Results 151 to 160 of about 153,321 (216)

A stand-alone ICln release module revealed by deconstructing the SMN complex with engineered Brr1. [PDF]

Nucleic Acids Res
Hu Y, Zhang J, Xu B, Wang Y, Mu L, Zhang R.   +5 more
europepmc   +1 more source

Research progress on the role of inflammatory mediators in the pathogenesis of epilepsy

Ibrain, Volume 11, Issue 1, Page 44-58, Spring 2025.
In the central nervous system, activated immune cells lead to the overproduction of inflammatory mediators through the corresponding signal pathway. Under the stimulation of inflammatory factors, neuroinflammation ultimately occurs. Overexpression of inflammatory mediators and activated immunocytes plays an important role in the emergence and ...
Yue Yu, Fei‐Ji Sun
wiley   +1 more source

RPAP3: Structural evolution, chaperone networks, and disease implications of a transcriptional Co-chaperone. [PDF]

J Biol Chem
Antonio LM, Ramos CHI.
europepmc   +1 more source

Development and validation of the gynecologic examination anxiety scale (GEAS): A 20‐item patient‐reported measure

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Gynecologic examinations often provoke anxiety, embarrassment, and a perceived loss of control. Valid, patient‐focused tools that specifically quantify examination‐related anxiety remain limited. This study developed and validated the gynecologic examination anxiety scale (GEAS). Methods In a methodological study conducted in Turkey (
Hacer Demirtop, Kerime Derya Beydağ, Aysu Yıldız Karaahmet   +2 more
wiley   +1 more source

An Exploratory Study of Heat Shock Protein Changes in Women with Unexplained Infertility. [PDF]

Int J Mol Sci
Alhalwachi Z, Sathyapalan T, Butler AE, Atkin SL.   +3 more
europepmc   +1 more source

A multiplex interactome of Ebola virus proteins reveals TM9SF2 as a cell‐surface attachment factor that promotes viral entry

iMetaOmics, EarlyView.
This study generates a comprehensive Ebola virus (EBOV)‐human protein–protein interactome, comprising 1728 core high‐confidence interactions. Further interactome analysis revealed the potential association of EBOV glycoprotein (GP) with the host factor TM9SF2. Subsequent mechanistic investigations confirmed that TM9SF2 functions as an attachment factor
Limin Shang, Shouwen Du, Yuchen Liu, Letian Li, Xi Wu, Yanzhi Yuan, Chaozhi Jin, Qingkun Mi, Yuhang Wang, Xiaoshuang Shi, Jiamin Wang, Guoqing Zhang, Yidan Ma, Weijin Huang, Jigang Wang, Jian Wang, Chang Li   +16 more
wiley   +1 more source

Synaptic Chaperone Dysfunction as a Convergent Mechanism in Neurodegenerative and Psychiatric Disorders. [PDF]

Neurosci Insights
Jean D, Li Y.
europepmc   +1 more source

Synthetic microbial communities for engineering climate‐smart biofertilizers

iMeta, EarlyView.
Global agricultural productivity is increasingly destabilized by climate change—driven droughts, floods, extreme heat, and severe storms. Although the climate‐smart agriculture (CSA) framework addresses these challenges, implementation has focused mainly on plant genetics and agronomic inputs, leaving the adaptive potential of the crop microbiome ...
Yan Liu, Yue Chen, Yanxue Yu, Che Ok Jeon, Mohammad Bahram, Junfeng Zhai, Hailei Wei, Fuqiang Wang, Xiaofeng Cao, Baolei Jia   +9 more
wiley   +1 more source

A proteome optimal allocation model for elucidating effects of temperature on bacterial growth. [PDF]

NPJ Syst Biol Appl
Wang D, Zhang Q, Shi H.
europepmc   +1 more source