Results 21 to 30 of about 92,867 (160)
Gut Microbiota and Chemical-Induced Acute Liver Injury
Background: Drug overdose or chemical exposures are the main causes of acute liver injury (ALI). Severe liver injury can develop into liver failure that is an important cause of liver-related mortality in intensive care units in most countries ...
Tao Chen, Tao Chen, Rui Li, Peng Chen
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Background: Several animal studies have shown the protective effect of silymarin (the extract of Silybum marianum seeds) against anti-tuberculosis drug-induced hepatotoxicity (ATDH). However, the knowledge of ATDH of silymarin in humans is scarce.
Ali Talebi +3 more
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Excessive stimulation of hepatotoxins and drugs often lead to acute liver injury, while treatment strategies for acute liver injury have been limited. Methyl 6-O-cinnamoyl-α-d-glucopyranoside (MCGP) is a structure modified compound from cinnamic acid, a ...
Qianqian Xu +13 more
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LIVER INJURY INDUCED BY HERBAL AND DIETARY SUPPLEMENTS: A POOLED ANALYSIS OF CASE REPORTS
Background: The intake of dietary supplements and medicinal plants is very popular worldwide. However, these products are not innocuous, and their intake can cause severe damage to health, especially liver injury. Objective: This study aims to describe
Michelle Hoff de ASSIS +3 more
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Trametes lactinea mycelia polysaccharides (TLMPS) have a wide range of bioactivities. The potential mechanisms of action of TLMPS against acute alcohol-induced liver injury in vivo were investigated by analyzing the physical and chemical properties of ...
Jinbin Hao +5 more
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Drug-induced liver injury due to tofacitinib: a case report
Background Drug-induced liver injury is an acute or chronic liver damage in response to drugs, herbals, and any chemical compound. Case presentation In the present work, liver failure following the use of tofacitinib was reported.
Masoud Mardani +3 more
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Drug induced liver injury: East versus West – a systematic review and meta-analysis [PDF]
Drug induced liver injury (DILI) may be different in the East compared to the West due to differing disease prevalence, prescribing patterns and pharmacogenetic profiles.
En Xian Sarah Low +3 more
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INFLUENCE OF HIGH-DOSE ATORVASTATIN ON BILE ACID METABOLISM IN MICE WITH LIVER INJURY AND RELATED MECHANISM [PDF]
Objective To investigate the influence of high-dose atorvastatin on bile acid metabolism in mice with liver injury and its mechanism. Methods A total of 40 specific pathogen-free male C57BL/6 mice were randomly divided into normal saline group (group A ...
XIA Feifei, SONG Bingxue, SONG Yuqing, TIAN Jiawei, YAN Hui, HUANG Yuxiao, XIN Hui, LIANG Hui
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Hyperin protects against cisplatin-induced liver injury in mice [PDF]
Purpose: To evaluate the effect of hyperin in cisplatin-induced liver injury in mice. Methods: Mice were pretreated with hyperin at doses of 25 mg/kg and 50 mg/kg, respectively, for six days, and intraperitoneal injection of cisplatin (40 mg/kg) was ...
Chengwei Niu +4 more
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