Results 181 to 190 of about 501,169 (342)

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

Advanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim, Ye‐Ji Kim, Seyoung Ryu, Daeui Park, Kyoung‐Sik Moon, Yu Bin Lee, Dong Ho Woo   +6 more
wiley   +1 more source

Sphingosine kinase inhibitor suppresses dendritic cell migration by regulating chemokine receptor expression and impairing p38 mitogen‐activated protein kinase

, 2007
In Duk Jung, Jun Sik Lee, Yong‐Joo Kim, Young‐Il Jeong, Chang‐Min Lee, Min Goo Lee, Soon‐Choel Ahn, Yeong‐Min Park   +7 more
openalex   +1 more source

Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists [PDF]

, 2018
Anna-Katharina Apel, R.K. Cheng, Christofer S. Tautermann, Michael Brauchle, Chia‐Ying Huang, Alexander Pautsch, Michael Hennig, Herbert Nar, Gisela Schnapp   +8 more
openalex   +1 more source

Data from An antagonist of the chemokine receptor CXCR4 induces mitotic catastrophe in ovarian cancer cells

, 2023
Joseph Kwong, Hagen Kulbe, Donald Wong, Probir Chakravarty, Frances R. Balkwill   +4 more
openalex   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

Chemokine Networks in Cutaneous T Cell Lymphoma: Tumor Microenvironment Remodeling and Therapeutic Targets. [PDF]

Curr Issues Mol Biol
Yu Z, Li F, Quan Y, Hu W, Zhang P, Xie X.   +5 more
europepmc   +1 more source

Prediction of Long-term Renal Allograft Outcome By Early Urinary CXCL10 Chemokine Levels

, 2015
Patricia Hirt‐Minkowski, Julie Ho, Ang Gao, Patrizia Amico, Michael Koller, Helmut Hopfer, David N. Rush, Peter Nickerson, Stefan Schaub   +8 more
openalex   +1 more source

The Differential Expression and Function of the Inflammatory Chemokine Receptor CXCR5 in Benign Prostatic Hyperplasia and Prostate Cancer [PDF]

, 2015
Lu Yang, Liang Gao, Yongji Chen, Zhuang Tang, Yuchun Zhu, Ping Han, Xiang Li, Qiang Wei   +7 more
openalex   +1 more source

Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges

Advanced Healthcare Materials, EarlyView.
This review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Fatma Moawad, Yasmine Ruel, Roxane Pouliot, Davide Brambilla   +3 more
wiley   +1 more source

Simulation-based inference of cell migration dynamics in complex spatial environments. [PDF]

NPJ Syst Biol Appl
Arruda J, Alamoudi E, Mueller R, Vaisband M, Molkenbur R, Merrin J, Kiermaier E, Hasenauer J.   +7 more
europepmc   +1 more source