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The distinct contribution of sternotomy to the systemic inflammatory response during children's heart surgery. [PDF]
Front ImmunolBierer JD +7 more
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Developmental & Comparative Immunology, 2004
Chemokines are small proteins that control cellular migration. An extensive family of these molecules has been described in mammals containing nearly 50 members. Within this family are four groups, each defined by the different spacing of two N-terminal cysteines, which form disulphide bonds with two other cysteine residues to create the tertiary ...
Kerry J, Laing, Christopher J, Secombes
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Chemokines are small proteins that control cellular migration. An extensive family of these molecules has been described in mammals containing nearly 50 members. Within this family are four groups, each defined by the different spacing of two N-terminal cysteines, which form disulphide bonds with two other cysteine residues to create the tertiary ...
Kerry J, Laing, Christopher J, Secombes
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2009
Tumor growth is restricted to approximately 2 microm diameters by simple dissociation of nutrients and oxygen. Hence, tumors require the formation of new blood vessels for further growth progression. This process is referred to as tumor neo-angiogenesis. The process of tumor neo-angiogenesis is directed by complex bidirectional interactions between the
Andreas, Hippe +2 more
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Tumor growth is restricted to approximately 2 microm diameters by simple dissociation of nutrients and oxygen. Hence, tumors require the formation of new blood vessels for further growth progression. This process is referred to as tumor neo-angiogenesis. The process of tumor neo-angiogenesis is directed by complex bidirectional interactions between the
Andreas, Hippe +2 more
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Chemokines, chemokine receptors and hematopoiesis
Immunological Reviews, 2000Hematopoiesis during steady state conditions is regulated and finely tuned by a network of cytokines and their effects on hematopoietic stem and progenitor cells and on accessory cells that influence the stem and progenitor cells. Amongst the numerous cytokines implicated in this regulation are members of the CC, CXC and C family of chemokines.
B S, Youn, C, Mantel, H E, Broxmeyer
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Cytokine & Growth Factor Reviews, 2001
Although chemokines were originally defined as host defense proteins it is now clear that their repertoire of functions extend well beyond this role. For example chemokines such as MGSA have growth regulatory properties while members of the CXC chemokine family can be mediators or inhibitors of angiogenesis and may be important targets for oncology ...
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Although chemokines were originally defined as host defense proteins it is now clear that their repertoire of functions extend well beyond this role. For example chemokines such as MGSA have growth regulatory properties while members of the CXC chemokine family can be mediators or inhibitors of angiogenesis and may be important targets for oncology ...
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Chemokines, Chemokine Receptors and Allergy
International Archives of Allergy and Immunology, 2001Chemokines are a group of cytokines that are responsible for the influx of blood cells, including T and B lymphocytes, monocytes, neutrophils, eosinophils and basophils, in allergic and other inflammatory conditions. They function as G protein-coupled chemotactic factors which also activate the cells with which they interact.
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Chemokines, chemokine receptors and pain
Trends in Immunology, 2005Many patients suffer from neuropathic pain as a result of injury to the peripheral nervous system (e.g. post-herpetic neuralgia or diabetic neuropathy) or to the central nervous system (e.g. spinal cord injury or stroke). The most distinctive symptom of neuropathic pain is allodynia, whereby normally non-painful stimuli, such as light touch, become ...
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Chemokines and Chemokine Receptors
1999Classic chemoattractants include complement components, formyl peptides and leukotriene B4. In addition, various cytokines are able to elicit directional migration of leukocytes. While molecules such as monocyte-colony stimulating factor or tumor necrosis factor also exert chemotactic activity, the main chemotactic cytokines are a superfamily of ...
A. Mantovani +6 more
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Chemokine–Chemokine Receptors in Cancer Immunotherapy
Immunotherapy, 2008A surge in interest in the chemokine-chemokine receptor network is probably related to the expanding roles that chemokines have now been identified to play in human biology, particularly immunity. Specific tissue microenvironments express distinct chemokines and both hematopoietic and nonhematopoietic cells have receptor expression profiles that permit
J. Stewart, Trina, J. Smyth, Mark
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