Results 321 to 330 of about 501,169 (342)

Chemokines and Chemokine Receptors

2001
The recruitment of cells to sites of inflammation is an essential component of the host inflammatory response. Cell recruitment relies on the coordinated action of cell activation, cell adhesion, chemoattraction, and transmigration across the endothelial barrier.
Andrew D. Luster, James MacLean
openaire   +1 more source

Chemokine sequestration by atypical chemokine receptors

Biochemical Society Transactions, 2006
Leucocyte migration is essential for robust immune and inflammatory responses, and plays a critical role in many human diseases. Chemokines, a family of small secreted protein chemoattractants, are of fundamental importance in this process, directing leucocyte trafficking by signalling through heptahelical G-protein-coupled receptors expressed by the ...
C A H, Hansell, C V, Simpson, R J B, Nibbs   +2 more
openaire   +2 more sources

Chemokines and chemokine receptors

2009
There is a structural and a functional classification of chemokines. The former includes four groups: CXC, CC, C and CX3C chemokines. There is a redundancy and binding promiscuity between chemokine receptors and their ligands. Recently, a functional classification distinguishing between inflammatory and homeostatic chemokines has been introduced ...
Zoltán Szekanecz, Alisa E. Koch
openaire   +1 more source

Chemokines and Chemokine Receptors in Scleroderma

International Archives of Allergy and Immunology, 2006
Scleroderma is a connective tissue disease with unknown etiology characterized by excessive deposition of extracellular matrix in the skin. Cellular infiltrates of certain immune cells and proinflammatory mediators are suggested to play a crucial role in cutaneous fibrosis, forming complicated networks between fibroblasts and immune cells via cell-cell
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Chemokines and Chemokine Receptors Encoded by Cytomegaloviruses

2008
CMVs carry several genes that are homologous to genes of the host organism. These include genes homologous to those encoding chemokines (CKs) and G protein-coupled receptors (GPCRs). It is generally assumed that these CMV genes were hijacked from the host genome during the long co-evolution of virus and host.
Beisser, PS, Lavreysen, H, Bruggeman, CA, Vink, Kees   +3 more
openaire   +2 more sources

Chemokine/Chemokine Receptor Nomenclature

Journal of Interferon & Cytokine Research, 2002
Kevin, Bacon, Marco, Baggiolini, Hal, Broxmeyer, Richard, Horuk, Ivan, Lindley, Alberto, Mantovani, Kouji, Maysushima, Philip, Murphy, Hisayuki, Nomiyama, Joost, Oppenheim, Antal, Rot, Thomas, Schall, Monica, Tsang, Robin, Thorpe, Jo, Van Damme, Meenu, Wadhwa, Osamu, Yoshie, Albert, Zlotnik, Kathy, Zoon   +18 more
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Introduction to Chemokines and Chemokine Antagonists

2004
Chemokines are small, soluble proteins with four conserved cysteines (Baggiolini et al. 1994, 1997). They consist of about 70–130 amino acids yielding molecular weights in the range of 7–15 kDa, and are synthesized with a leader sequence of 20–25 amino acids, which is cleaved off before release.
openaire   +2 more sources

Cancer and Chemokines

2016
Chemokines are a large family of secreted cytokines whose main function is to mediate leukocyte directional migration. Most cancers contain chemokines and express chemokine receptors as a consequence of the activity of deregulated transcription factors or tumor-suppressor genes.
Caronni N., Savino B., Recordati C., Villa A., Locati M., Bonecchi R.   +5 more
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Chemokines and cancer

International Journal of Cancer, 2004
AbstractThe chemokines and their receptors are a superfamily of small secreted molecules that control the migration of many cell types in the body. Several years ago it became clear that some chemokines and receptors regulate the migration of certain cells in the lymphoid system, and this raised the possibility that chemokines could also control the ...
openaire   +3 more sources

Chemokines

The Lancet, 1994
MANTOVANI A., SOZZANI, Silvano
openaire   +5 more sources