Results 141 to 150 of about 63,435 (292)
Advanced Science, EarlyView.Neuron‐derived MIF binds VCAM1 on gastric cancer cells and activates ERK/STAT3 signaling, leading to CXCL8 transcription and secretion. Tumor‐derived CXCL8 subsequently stimulates neuronal CXCR2 to enhance MIF production, establishing a self‐amplifying MIF–VCAM1–CXCL8 positive‐feedback loop that promotes perineural invasion, tumor progression, and ...
Xunjun Li +13 more
wiley +1 more source
Sympathectomy decreases pain behaviors and nerve regeneration by downregulating monocyte chemokine CCL2 in dorsal root ganglia in the rat tibial nerve crush model. [PDF]
Pain, 2022 Zhu X +4 more
europepmc +1 more source
Reduced expression of chemokine (C-C motif) ligand-2 (CCL2) in ovarian adenocarcinoma
, 2005 Chemokine (C-C motif) ligand-2 (CCL2) is a chemoattractant and activator of macrophages and is a key determinant of the macrophage infiltrate into tumours.
Ramm, G. A. +9 more
core +1 more source
Advanced Science, EarlyView.Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim +2 more
wiley +1 more source
Role of CCL2/CCR2 axis in pulmonary fibrosis induced by respiratory viruses
Journal of Microbiology, Immunology and InfectionRespiratory virus infection is an important cause of both community acquired pneumonia and hospital-acquired pneumonia. Various respiratory viruses, including influenza virus, avian influenza virus, respiratory syncytial virus (RSV), SARS-CoV, MERS-CoV ...
Shuangyan Li +3 more
doaj +1 more source
Chemokines in Kawasaki disease: measurement of CCL2, CCL22 and CXCL10.
Asian Pacific journal of allergy and immunology, 2005 Kawasaki disease (KD) is a childhood-onset vascular disease. In order to determine whether KD is associated with altered chemokine production, we measured CCL2, CCL22, and CXCL10 levels in the serum of KD patients and healthy control subjects. The mean serum concentration of CCL2 in KD subjects was 829.0 +/- 388.2 pg/ml, significantly higher than that ...
Yasufumi, Shikishima +2 more
openaire +1 more source
Research progress on biomarkers of traumatic brain injury
Animal Models and Experimental Medicine, EarlyView.Traumatic brain injury: From primary insult to secondary neuroinflammation and degeneration. Abstract Traumatic brain injury (TBI) is a common disorder of the nervous system and has become a leading cause of death and disability worldwide, imposing a substantial burden on patients and their social circles. Its main symptoms include dyskinesia, language
Xuting Shen +8 more
wiley +1 more source
The role of the chemokine “CCL2” in central cardiovascular control
, 2019 © 2019 Khalid ElsaafienThe cardiovascular system is under the constant control of a specialised neural network spanning a number of brain regions. This includes a distinct population of neurons found within the paraventricular nucleus (PVN) of the ...
Elsaafien, Khalid
core
Animal Models and Experimental Medicine, EarlyView.Four aspiration methods (UV, IN, IT, and OA) were compared, and OA was identified as the most effective delivery technique. A chronic aspiration pneumonia model was then established through repeated OA of food suspension or gastric contents. Integrated analyses, including micro‐CT, histopathology, cytokine profiling, and RNA sequencing, revealed ...
Qianwen Li +4 more
wiley +1 more source
Conditional deletion of Ccl2 in smooth muscle cells does not reduce early atherosclerosis in mice
Atherosclerosis PlusBackground and aims: C–C motif chemokine ligand 2 (CCL2) is a pro-inflammatory chemokine important for monocyte recruitment to the arterial wall and atherosclerotic plaques. Global knockout of Ccl2 reduces plaque formation and macrophage content in mice,
Stine Gunnersen +5 more
doaj +1 more source