Results 11 to 20 of about 3,367 (129)

Trophoblasts-derived chemokine CCL24 promotes the proliferation, growth and apoptosis of decidual stromal cells in human early pregnancy. [PDF]

International journal of clinical and experimental pathology, 2013
Chemokine CCL24 is the second member of eotaxins, a group of eosinophils' selectively chemoattractants. Via binding to its only receptor CCR3, CCL24 mainly mediates atopic disorders, parasitic infections and systemic diseases. It is well-known that CCR3 is expressed at the maternal-fetal interface; nevertheless whether CCL24 is located there and which ...
Hui, Li, Yuan-Hua, Huang, Ming-Qing, Li, Yu-Han, Meng, Xuan, Chen, Jun, Shao, Chuan-Ling, Tang, Mei-Rong, Du, Li-Ping, Jin, Da-Jin, Li   +9 more
openaire   +2 more sources

A meta-analysis of chemokines in alopecia areata: recruiting immune cells toward the hair follicle [PDF]

Frontiers in Immunology
A deeper understanding of the immune-based pathogenesis of alopecia areata is essential for the development of novel targeted therapies. Compared to cytokines, chemokines exhibit substantially higher serum concentrations, offering a more robust approach ...
Elise Van Caelenberg, Elise Van Caelenberg, Arno Belpaire, Arno Belpaire, Nanja van Geel, Nanja van Geel, Reinhart Speeckaert, Reinhart Speeckaert   +7 more
doaj   +2 more sources

CC chemokine receptor 3 (CCR3); eotaxin-1 (CCL11); eotaxin-2 (CCL24); eotaxin-3 (CCL26) [PDF]

Science-Business EXchange, 2009
exaly   +2 more sources

Plasma inflammatory biomarker profiles across the Alzheimer's disease spectrum in the Bio-Hermes cohort. [PDF]

Alzheimers Dement
Abstract INTRODUCTION Inflammation contributes to Alzheimer's disease (AD), but its stage‐specific and amyloid‐dependent patterns remain unclear. METHODS We analyzed 964 participants from the Bio‐Hermes cohort (cognitively normal [CN] = 404, mild cognitive impairment [MCI] = 302, mild AD = 258). Plasma levels of 32 cytokines, neurofilament light chain (
Hussain Z, Ng D, Leighton S, Deligianni F, Ritchie C, Cavanagh J.   +5 more
europepmc   +2 more sources

Large chemokine binding spectrum of human and mouse atypical chemokine receptor GPR182 (ACKR5)

Frontiers in Pharmacology, 2023
Atypical chemokine receptors (ACKRs) play pivotal roles in immune regulation by binding chemokines and regulating their spatial distribution without inducing G-protein activation.
Remy Bonnavion, Remy Bonnavion, Shangmin Liu, Haruya Kawase, Kenneth Anthony Roquid, Stefan Offermanns, Stefan Offermanns, Stefan Offermanns, Stefan Offermanns   +8 more
doaj   +1 more source

The Role of CCL24 in Systemic Sclerosis

Rambam Maimonides Medical Journal, 2023
Systemic sclerosis (SSc) is a chronic immune-mediated disease characterized by microangiopathy, immune dysregulation, and progressive fibrosis of the skin and internal organs.
Hilit Levy, Udi Gluschnaider, Alexandra Balbir-Gurman   +2 more
doaj   +1 more source

Macrophage-Derived CCL24 Promotes Cardiac Fibrosis Via Fibroblast CCR3 [PDF]

Circulation Research
Haiguang Wang, Samuel Dudley, Adam Herman   +2 more
exaly   +2 more sources

Single-Cell RNA-Seq Reveals a Crosstalk between Hyaluronan Receptor LYVE-1-Expressing Macrophages and Vascular Smooth Muscle Cells

Cells, 2022
Background: Atherosclerosis is a chronic inflammatory disease where macrophages participate in the progression of the disease. However, the role of resident-like macrophages (res-like) in the atherosclerotic aorta is not completely understood. Methods: A
Fabienne Burger, Daniela Baptista, Aline Roth, Karim J. Brandt, Rafaela Fernandes da Silva, Fabrizio Montecucco, François Mach, Kapka Miteva   +7 more
doaj   +1 more source

Chemokine CCL24 promotes the growth and invasiveness of trophoblasts through ERK1/2 and PI3K signaling pathways in human early pregnancy [PDF]

Reproduction, 2015
Abstract Chemokine CCL24, acting through receptor CCR3, is a potent chemoattractant for eosinophil in allergic diseases and parasitic infections. We recently reported that CCL24 and CCR3 are co-expressed by trophoblasts in human early pregnant uterus.
Hui, Li, Yu-Han, Meng, Wen-Qing, Shang, Li-Bing, Liu, Xuan, Chen, Min-Min, Yuan, Li-Ping, Jin, Ming-Qing, Li, Da-Jin, Li   +8 more
openaire   +2 more sources

Involvement of Eotaxins (CCL11, CCL24, CCL26) in Pathogenesis of Osteopenia and Osteoporosis

Iranian Journal of Public Health, 2020
Background: The purpose of this study was to investigate the role of eotaxin family members including C-C motif chemokine 11 (CCL11), C-C motif chemokine 24 (CCL24), and C-C motif chemokine 26 (CCL26) as the subgroups of CC-chemokine in patients affected
Hadis AHMADI, Hossein KHORRAMDELAZAD, Gholamhossein HASSANSHAHI, Mitra ABBASI FARD, Zahra AHMADI, Mojgan NOROOZI KARIMABAD, Majid MOLLAHOSSEINI   +6 more
doaj   +1 more source