Results 21 to 30 of about 3,367 (129)

Integration of single-cell sequencing and bulk expression data reveals chemokine signaling pathway in proliferating cells is associated with the survival outcome of osteosarcoma

BMC Medical Genomics, 2023
Background Osteosarcoma, as the most common primary bone malignancy, is urgent to be well-studied on the biomarkers and therapeutic targets to improve the five-year survival rate.
Lin Yu, Sun Hongyu, Chen Yuxi
doaj   +1 more source

Seric chemokines and chemokine receptors in eosinophils during acute human schistosomiasis mansoni

Memorias do Instituto Oswaldo Cruz, 2010
The recruitment of circulating eosinophils by chemokines and chemokine receptors plays an important role in the inflammation process in acute human schistosomiasis.
Denise Silveira-Lemos, Andréa Teixeira-Carvalho, Olindo Assis Martins-Filho, Adriano Luiz Souza-Soares, Pollyanna Castro-Silva, Matheus Fernandes Costa-Silva, Pedro Henrique Gazzinelli Guimarães, Helena Barbosa Ferraz, Lúcia Alves Oliveira-Fraga, Mauro Martins Teixeira, Rodrigo Corrêa-Oliveira   +10 more
doaj   +1 more source

The established chemokine-related prognostic gene signature in prostate cancer: Implications for anti-androgen and immunotherapies

Frontiers in Immunology, 2022
BackgroundProstate cancer (PCa) was one of the most common malignancies among men, while the prognosis for PCa patients was poor, especially for patients with recurrent and advanced diseases.Materials and methodsFive PCa cohorts were downloaded from The ...
Lei Chen, Lei Chen, Lei Chen, Yi Zheng, Yi Zheng, Yi Zheng, Changqin Jiang, Changqin Jiang, Changqin Jiang, Cheng Yang, Cheng Yang, Cheng Yang, Li Zhang, Li Zhang, Li Zhang, Chaozhao Liang, Chaozhao Liang, Chaozhao Liang   +17 more
doaj   +1 more source

Establishing Classification Tree Models in Rheumatoid Arthritis Using Combination of Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry and Magnetic Beads

Frontiers in Medicine, 2021
Background: There is no simple method for early diagnosis and evaluation of rheumatoid arthritis (RA). This study aimed to determine potential biomarkers and establish diagnostic patterns for RA using proteomic fingerprint technology combined with ...
Dan Ma, Nana Liang, Liyun Zhang
doaj   +1 more source

Higher expression of CCL2, CCL4, CCL5, CCL21, and CXCL8 chemokines in the skin associated with parasite density in canine visceral leishmaniasis. [PDF]

PLoS Neglected Tropical Diseases, 2012
BACKGROUND: The immune response in the skin of dogs infected with Leishmania infantum is poorly understood, and limited studies have described the immunopathological profile with regard to distinct levels of tissue parasitism and the clinical progression
Daniel Menezes-Souza, Renata Guerra-Sá, Cláudia Martins Carneiro, Juliana Vitoriano-Souza, Rodolfo Cordeiro Giunchetti, Andréa Teixeira-Carvalho, Denise Silveira-Lemos, Guilherme Corrêa Oliveira, Rodrigo Corrêa-Oliveira, Alexandre Barbosa Reis   +9 more
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Elevated Plasma Chemokines for Eosinophils in Neuromyelitis Optica Spectrum Disorders during Remission

Frontiers in Neurology, 2018
BackgroundA prominent pathological feature of neuromyelitis optica spectrum disorders (NMOSD) is markedly greater eosinophilic infiltration than that seen in other demyelinating diseases, like multiple sclerosis (MS).
Yanping Tong, Yanping Tong, Tao Yang, Tao Yang, Jingwen Wang, Tianyou Zhao, Lei Wang, Yuezhi Kang, Cuicui Cheng, Yongping Fan, Yongping Fan   +10 more
doaj   +1 more source

Milligram production and biological activity characterization of the human chemokine receptor CCR3. [PDF]

PLoS ONE, 2013
Human chemokine receptor CCR3 (hCCR3) belongs to the G protein-coupled receptors (GPCRs) superfamily of membrane proteins and plays major roles in allergic diseases and angiogenesis.
Mingqing Wang, Baosheng Ge, Renmin Li, Xiaoqiang Wang, Jun Lao, Fang Huang   +5 more
doaj   +1 more source

NF-κB-Mediated CCL20 Reigns Dominantly in CXCR2-Driven Ovarian Cancer Progression. [PDF]

PLoS ONE, 2016
Ovarian cancer is an inflammation-associated malignancy with a high mortality rate. CXCR2 expressing ovarian cancers are aggressive with poorer outcomes. We previously demonstrated that CXCR2-driven ovarian cancer progression potentiated NF-κB activation
Rosa Mistica C Ignacio, Syeda M Kabir, Eun-Sook Lee, Samuel E Adunyah, Deok-Soo Son   +4 more
doaj   +1 more source

Assessment of the diagnostic accuracy of eotaxin-2 as a marker for preterm prelabour rupture of membranes [PDF]

Scripta Medica
Background/Aim: Preterm pre-labour rupture of the membranes could be caused by the change in local cytokines concentration due to inflammatory or infectious conditions.
Ali Miami Abdul Hassan, Ali Naz Mazin
doaj   +1 more source

Functional expression of CCL8 and its interaction with chemokine receptor CCR3

BMC Immunology, 2017
Background Chemokines and their cognate receptors play important role in the control of leukocyte chemotaxis, HIV entry and other inflammatory diseases.
Baosheng Ge, Jiqiang Li, Zhijin Wei, Tingting Sun, Yanzhuo Song, Naseer Ullah Khan   +5 more
doaj   +1 more source