Results 21 to 30 of about 369,183 (362)

Chemokines and their receptors in Atherosclerosis [PDF]

open access: yesJournal of Molecular Medicine, 2015
Atherosclerosis, a chronic inflammatory disease of the medium- and large-sized arteries, is the main underlying cause of cardiovascular diseases (CVDs) most often leading to a myocardial infarction or stroke. However, atherosclerosis can also develop without this clinical manifestation.
Yvonne Döring   +3 more
openaire   +3 more sources

Functional diversity of chemokines and chemokine receptors in response to viral infection of the central nervous system. [PDF]

open access: yes, 2006
Encounters with neurotropic viruses result in varied outcomes ranging from encephalitis, paralytic poliomyelitis or other serious consequences to relatively benign infection.
A. Meyer   +108 more
core   +1 more source

Chemokines and Chemokine Receptors in Multiple Sclerosis [PDF]

open access: yesMediators of Inflammation, 2014
Multiple sclerosis is an autoimmune disease with classical traits of demyelination, axonal damage, and neurodegeneration. The migration of autoimmune T cells and macrophages from blood to central nervous system as well as the destruction of blood brain barrier are thought to be the major processes in the development of this disease.
Wenjing Cheng, Guangjie Chen
openaire   +3 more sources

The Effect of N-Terminal Cyclization on the Function of the HIV Entry Inhibitor 5P12-RANTES. [PDF]

open access: yes, 2017
Despite effective treatment for those living with Human Immunodeficiency Virus (HIV), there are still two million new infections each year. Protein-based HIV entry inhibitors, being highly effective and specific, could be used to protect people from ...
F Nguyen, Anna   +3 more
core   +2 more sources

High expression of C-X-C chemokine receptor 4 and Notch1 is predictive of lymphovascular invasion and poor prognosis in lung adenocarcinoma

open access: yesTumor Biology, 2017
C-X-C chemokine receptor 4 and Notch1 have been shown to play oncogenic role individually. This study aimed to determine the combinatorial role of C-X-C chemokine receptor 4 and Notch1 in lung adenocarcinoma.
Zhuangzhuang Cong   +7 more
doaj   +1 more source

Chemokines and chemokine receptors expression in the lesions of patients with American cutaneous leishmaniasis

open access: yesMemorias do Instituto Oswaldo Cruz, 2013
American cutaneous leishmaniasis (ACL) presents distinct active clinical forms with different grades of severity, known as localised (LCL), intermediate (ICL) and diffuse (DCL) cutaneous leishmaniasis. LCL and DCL are associated with a polarised T-helper
Nilka Luisa Diaz   +2 more
doaj   +1 more source

Microarray analyses demonstrate the involvement of type i interferons in psoriasiform pathology development in D6-deficient mice [PDF]

open access: yes, 2013
The inflammatory response is normally limited by mechanisms regulating its resolution. In the absence of resolution, inflammatory pathologies can emerge, resulting in substantial morbidity and mortality.
Baldwin, H.M.   +9 more
core   +1 more source

Phenotyping renal leukocyte subsets by four-color flow cytometry: Characterization of chemokine receptor expression [PDF]

open access: yes, 2003
To investigate mechanisms of cell-mediated injury in renal inflammatory disease it is critical to determine the surface phenotype of infiltrating renal leukocyte subsets.
Anders, Hans-Joachim   +5 more
core   +1 more source

Multifaceted Roles of Chemokine C-X-C Motif Ligand 7 in Inflammatory Diseases and Cancer

open access: yesFrontiers in Pharmacology, 2022
Over recent years, C-X-C motif ligand 7 (CXCL7) has received widespread attention as a chemokine involved in inflammatory responses. Abnormal production of the chemokine CXCL7 has been identified in different inflammatory diseases; nevertheless, the ...
Qianmiao Wu   +3 more
doaj   +1 more source

Chemokines, Chemokine Receptors, and Allograft Rejection [PDF]

open access: yesImmunity, 2001
Chemokines are pivotal mediators in allograft rejection by virtue of their activity as regulators of leukocyte movement, adhesion, and effector function. Because the regulation of effector cell infiltration is complex, it is difficult to dissect the relative role of each chemokine in the inflammatory processes leading to allograft rejection, especially
Peter J. Nelson, Alan M. Krensky
openaire   +3 more sources

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