Results 101 to 110 of about 18,475 (201)
FEBS Open Bio, Volume 16, Issue 7, Page 1244-1258, July 2026.The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
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Advanced Healthcare Materials, Volume 15, Issue 27, 17 July 2026.Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha +9 more
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Inflammatory signatures in the spectrum of myeloid diseases
HemaSphere, Volume 10, Issue 7, July 2026.Abstract Dysregulated innate immunity contributes to clonal cytopenias and myeloid neoplasms, but its extent across disease stages and clinical relevance remain incompletely defined. We analyzed plasma ASC/NLRP3 double‐positive (DP) specks, ASC single‐positive (SP) specks, and 45 cytokines in 223 patients with idiopathic cytopenias of undetermined ...
Alice Ibbotson +12 more
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Periodontitis during pregnancy: The effect on the gut microbiome and intestinal inflammation
Journal of Periodontology, Volume 97, Issue 7, Page 1587-1603, July 2026.Abstract Background Periodontitis has been epidemiologically associated with adverse pregnancy outcomes, but causality remains difficult to establish in humans due to confounding factors. This study uses a controlled murine model to examine the effects of experimentally induced periodontitis on the composition of the gut microbiota and gastrointestinal
Richard Bright +9 more
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HeliyonChemokines regulate the trophoblast dysfunction involved in the occurrence and development of pathological pregnancy, including missed abortions. In particular, CXC chemokine receptor type 5 mediates cell proliferation, migration, and inflammation ...
Yanan Zhi +6 more
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Aging Cell, Volume 25, Issue 7, July 2026.Oxidative stress induces GLS2‐dependent IL‐1β secretion in senescent macrophages, promoting SCC invasion through the IL‐1β/IL‐1R2 axis. Targeting IL‐1β suppresses invasion more effectively than GLS2 inhibition, highlighting a potential therapeutic strategy for SCC.
Shimeng Wang +7 more
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Expression of IP-10 Chemokine is Regulated by Pro-inflammatory Cytokines in Cultured Hepatocytes
Iranian Journal of Allergy, Asthma and Immunology, 2007 Chemokines are classified in four distinct groups as CXC, CC, CX3C and C, depending on the presence or absence of a motif called ELR (Arg-Leu-Glu) before the first cysteine residue in their structure. CXC chemokines are also subdivided into ELR+ and ELR-.
Gholamhossein Hassanshahi +4 more
doaj
Evidence for a Two‐Step Model for Activation of GPR25 by the Chemoattractant CXCL17
Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 1, July 2026.ABSTRACT CXCL17 was recently reported to activate GPR25, a receptor expressed by T‐regulatory cells. Although classified as a chemokine, the activity of CXCL17 is ablated by minor C‐terminal truncation, suggesting a novel mode of receptor activation. We set out to test this hypothesis by mutagenesis. GPR25 was expressed in the murine pre‐B cell line L1.
Wuqing Yang +2 more
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Type I and II Interferon Signalling Characterizes the Transcriptional Landscape of Sweet Syndrome
Experimental Dermatology, Volume 35, Issue 7, July 2026.ABSTRACT Sweet syndrome (SS) is an autoinflammatory neutrophilic dermatosis characterized by abrupt‐onset inflammatory skin lesions and systemic symptoms, yet its molecular pathogenesis remains incompletely defined. To delineate disease‐specific inflammatory programmes, we performed NanoString‐based transcriptomic analysis of SS skin lesions and ...
Laura Calabrese +12 more
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A guide to the types, structures, and multifaceted functions of matrix metalloproteinases in cancer
The FEBS Journal, Volume 293, Issue 13, Page 3717-3757, July 2026.Matrix metalloproteinases (MMPs) orchestrate cancer progression and metastasis through proteolytic and non‐proteolytic actions. By remodeling the tumor microenvironment, enhancing growth factor availability, and modulating cell behavior, MMPs promote proliferation, migration or invasion, and epithelial‐to‐mesenchymal transition. Alongside extracellular
Zoi Piperigkou +4 more
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