Results 91 to 100 of about 18,475 (201)

Innovations in Obesity Treatment: Beyond Adipose Tissue Dysfunction

Obesity Reviews, EarlyView.
Obesity drives chronic inflammation, insulin resistance, type 2 diabetes, and cancer development through adipocyte dysfunction. Addressing this multisystemic disorder requires integrated strategies beyond diet and exercise, such as thermogenesis activation via menthol or capsinoids and appetite control through GLP‐1/GIP agonists and neuromodulation to ...
Jesica Martínez‐Godfrey, Irene Pomares‐Bri, Paula de Juan‐Maciá, Mariló Olivares‐Vicente, Enrique Barrajón‐Catalán, Vicente Micol, Enrique Roche, María Herranz‐López   +7 more
wiley   +1 more source

ELR positive CXCL chemokines are highly expressed in an animal model of ulcerative colitis

Journal of Inflammation Research, 2019
Mohammad Amin Boshagh,1,2 Poorya Foroutan,1,2 Mohammad Raman Moloudi,3 Shohreh Fakhari,1 Parisa Malakouti,1 Bahram Nikkhoo,1 Ali Jalili1,21Cancer and Immunology Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran; 2Department of ...
Boshagh MA, Foroutan P, Moloudi MR, Fakhari S, Malakouti P, Nikkhoo B, Jalili A   +6 more
doaj  

Understanding exosomes in facial esthetics and skin aging

Periodontology 2000, EarlyView.
Abstract Background Skin aging is a multifactorial process mediated by intrinsic (genetic and metabolic) and extrinsic (environmental) factors leading to functional and structural deterioration, including wrinkles, loss of collagen and elastin, as well as various pigmentation disorders.
Richard J. Miron, Catherine Davies, Anton Sculean, Paras Ahmad   +3 more
wiley   +1 more source

The role of chemokines in Schistosoma mansoni infection: insights from human disease and murine models

Memorias do Instituto Oswaldo Cruz, 2006
Chemokines are a superfamily of low-molecular-weight cytokines that were initially described for their chemoattractant activity. It is now clear chemokines have several other activities that modulate immune processes.
Adriano LS Souza, Silvio R Sousa-Pereira, Mauro M Teixeira, José R Lambertucci, Antonio L Teixeira   +4 more
doaj   +1 more source

Septic Shock and Prognosis in Dogs and Cats With Sepsis—Consensus Definition and Clinical Criteria

Journal of Veterinary Emergency and Critical Care, EarlyView.
ABSTRACT Death from sepsis results from progressive organ dysfunction. Early recognition of increased illness severity or deterioration in clinical status enables timely interventions that can improve outcomes. We aimed to define septic shock by consensus and to use the existing literature to identify associated clinical and clinicopathologic ...
Robert Goggs, Stefano Cortellini, Amy E. DeClue, Massimo Giunti, Kate Hopper, Julie M. Menard, Rodrigo C. Rabelo, Elizabeth A. Rozanski, Claire R. Sharp, Deborah C. Silverstein, Virginia Sinnott‐Stutzman, Giacomo Stanzani, John Bourgeois, Erik Fausak   +13 more
wiley   +1 more source

Stromal Cell‐Derived Factor‐1α (SDF‐1α)‐Gene Activated Scaffold and Angiogenesis Process in Tissue Engineering: A Systematic Review and Meta‐Analysis of in Vitro Studies

MedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
The current systematic review revealed that stromal cell‐derived factor‐1α (SDF‐1α)‐gene‐activated scaffolds have a beneficial impact on promoting SDF‐1α gene expression and protein production. However, this effect is not observed for vascular endothelial growth factor (VEGF) gene expression and protein quantity and endothelial formation, which may be ...
Tungki Pratama Umar, Dessy Agustini, Sandy Hasan, Rohan Sabloak   +3 more
wiley   +1 more source

Pro-inflammatory cytokines and CXC chemokines as game-changer in age-associated prostate cancer and ovarian cancer: Insights from preclinical and clinical studies' outcomes

Pharmacological Research
Prostate cancer (PC) and Ovarian cancer (OC) are two of the most common types of cancer that affect the reproductive systems of older men and women. These cancers are associated with a poor quality of life among the aged population.
Amin Ullah, Yongxiu Chen, Rajeev K. Singla, Dan Cao, Bairong Shen   +4 more
doaj   +1 more source

The Dual Role of the Gut Microbiota in Cancer Chemoresistance

MicrobiologyOpen, Volume 15, Issue 4, August 2026.
Comparison between Microbiota and Cancer therapy. ABSTRACT Chemoresistance is one of the primary reasons that cancer chemotherapy fails to deliver successful treatment outcomes and contributes to poor overall survival rates for patients with cancer. New research has begun to shed light on the effects of the gut microbiome (GM).
Hamed Tahmasebi, Aisa Bahar, Meisam Khazaei, Mohammad Reza Arabestani   +3 more
wiley   +1 more source

Chemokines in Alzheimer's Disease: Early Defence, Late Damage and the Impact of Sex and Infection

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 2, August 2026.
ABSTRACT Chemokines constitute a versatile signalling network maintaining homeostasis and glia–neuron communication in the healthy brain but become progressively dysregulated during aging and Alzheimer's disease (AD). This review examines how chemokine systems transition from tightly regulated homeostatic signals to drivers of chronic neuroinflammation
Blanca I. Aldana, Kristine Freude
wiley   +1 more source

Chemokines and Their Role in Parasitic Diseases

European Journal of Inflammation, 2004
Chemotactic cytokines (chemokines), the intercellular mediators, produced and released by a wide variety of cell types, are a group of small secreted proteins (8–10 KDa), which mediate host response to invading organisms (viruses, bacteria, parasites ...
S. Frydas, E. Karagouni, E. Papadopoulos, M. Hatzistilianou, S. Pappas, N. Papaioannou   +5 more
doaj   +1 more source