Implications of chemokine receptors and inflammatory lipids in cancer
Johannes Rolin, Azzam A Maghazachi Department of Physiology, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway Abstract: Inflammatory lipids receive much attention due to their important biological activities ...
Rolin J, Maghazachi AA
doaj
Bioengineering tumor‐stroma pancreatic cancer models with potential to emulate the native immunosuppressive tumor microenvironment. Cancer‐on‐a‐bead models exhibited higher relevance for screening immunotherapies and modulating the protumoral PDAC microenvironment. ABSTRACT Pancreatic cancer is notably resistant to treatment, primarily due to its dense
Maria V. Monteiro +4 more
wiley +1 more source
The Stromal Cell–Derived Factor-1 Chemokine Is a Potent Platelet Agonist Highly Expressed in Atherosclerotic Plaques [PDF]
Sylvie Abi-Younes +5 more
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A novel method that combines 3D printing and organ‐on‐chip technology enables the creation of hollow channels lined with endothelial cells through a fibroblast‐populated connective tissue matrix. The model supports stable metabolic culture conditions, angiogenic sprouting, and immune cell migration, thereby demonstrating an easy and versatile method to
Jonas Jäger +7 more
wiley +1 more source
Cutting Edge: The Silent Chemokine Receptor D6 Is Required for Generating T Cell Responses That Mediate Experimental Autoimmune Encephalomyelitis [PDF]
Li‐Ping Liu +8 more
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A Human‐Based Skin‐Lymphoreticular Model‐on‐Chip to Emulate Inflammatory Skin Conditions
A human‐based lymphoreticular (LR) model was developed through guided self‐assembly and integrated in a skin‐lymphoreticular co‐culture in a microfluidic organ‐on‐chip to mimic interactions between skin and its draining lymph nodes. The human‐based skin‐lymphoreticular model resembles a minimally functional unit that allows to study interactions ...
Zheng Tan +3 more
wiley +1 more source
Structural basis of chemokine interactions with heparan sulfate, chondroitin sulfate, and dermatan sulfate [PDF]
Krishna Mohan Sepuru +1 more
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Microphysiological Systems of Lymphatics and Immune Organs
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain +2 more
wiley +1 more source
The chemokine
Skye C McIver +5 more
openalex +1 more source
Chemokine Ligand 2 – Chemokines Receptor 2 As A Noval Drug Target [PDF]
Kinjal S. Gamit
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