International Journal of Cancer, Volume 158, Issue 5, Page 1156-1165, 1 March 2026.Abstract Tumor‐infiltrating B cells (TIBs) exhibit dual roles in the tumor microenvironment (TME) of solid tumors. While they can enhance anti‐tumor immunity through antibody production and immune activation, certain subsets—such as regulatory B cells (Bregs) and immunosuppressive plasma cells—contribute to immune evasion by secreting inhibitory ...
Zhitong Li +5 more
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Circulating plasma gelsolin and MRI-based radiomics as biomarkers of platinum resistance in epithelial ovarian cancer: building a multiparameteric prediction algorithm. [PDF]
J Ovarian ResGerber E +8 more
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MedComm – Biomaterials and Applications, Volume 5, Issue 1, March 2026.The review provides a comprehensive analysis of microbiome‐mediated oncogenic mechanisms in various cancers, emphasizing the unique therapeutic strategies facilitated by nanotechnology. It aims to fill this gap by systematically reviewing nanotechnology‐driven strategies for microbiome elimination, with a focus on their ability to improve the cold TME ...
Yumei Gan, Yan Zhang, Xia Dong, Feng Lv
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A DNA Nanomachine Modulates the Stemness-Associated Signaling Pathways for Overcoming Chemoresistance by Temporally Programming Drug Release. [PDF]
Research (Wash D C)Chen J +8 more
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Local Anesthetics in Cancer: Mechanisms and Translational Perspectives
MedComm – Oncology, Volume 5, Issue 1, March 2026.Local anesthetics demonstrate multifaceted antitumor effects that collectively contribute to cancer suppression. Beyond canonical sodium channel blockade, these agents exert the following pharmacological actions: inhibition of tumor cell proliferation, suppression of migration and invasion, induction of proapoptotic pathways, attenuation of ...
Wan‐li Wang +4 more
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AVIL promotes osteosarcoma progression and cisplatin resistance via ARP2/3-mediated DNA damage repair. [PDF]
Transl OncolChen Z +9 more
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Unraveling Lysosomal Exocytosis: From Molecular Mechanisms to Physiological Functions
Traffic, Volume 27, Issue 1, March 2026.Lysosomal exocytosis is propelled by specific molecular mechanisms that direct its microtubule‐dependent transport and subsequent fusion with the plasma membrane. This process fulfills essential physiological functions such as plasma membrane repair, maintenance of cellular homeostasis, and participation in signal transduction.
Shanshan Jiang +7 more
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LSR overexpression induces chemoresistance in triple negative breast cancer cells through MDR1 upregulation and apoptosis attenuation. [PDF]
PLoS OneZhao M, Ma Z, Parris AB, Yang X.
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The role of cytokines in ovarian cancer drug resistance
International Journal of Cancer, Volume 158, Issue 4, Page 821-834, 15 February 2026.Abstract Ovarian cancer is the leading cause of death among women diagnosed with female reproductive system cancers. While significant advances have been made in treating various types of cancer, progress in ovarian cancer treatment over the past 20 years has been minimal, and the treatment course of ovarian cancer is not linear. Although many patients
Lu Wang +7 more
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Co-targeting MRPS7-23 synergistically enhances cisplatin efficacy to suppress nasopharyngeal carcinoma growth and metastasis. [PDF]
Int J Biol SciCao Z +16 more
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