Results 201 to 210 of about 99,840 (283)

MAP3K3 Contributes to Myocardial Ischemia/Reperfusion Injury by Promoting Myeloid Cell Diapedesis through TAL1/JAM-A Pathway. [PDF]

Theranostics
Hu S, Zhang J, Wang J, Li C, Wang Y, Liang J, Huang R, Yang J, Gao Y, Qu Y, Yang H, Qian J, Tang W, Cao J, Zhang F, Ge J.   +15 more
europepmc   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, Volume 13, Issue 3, 14 January 2026.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

Four key inflammatory pathways and targets in diabetic foot ulcers explored through data-driven analysis. [PDF]

J Vasc Surg Venous Lymphat Disord
Feng JY, Ju S.
europepmc   +1 more source

Stress‐Induced Activation of Prolactin‐NR4A1‐Midkine Axis Exacerbates Skin Inflammation

Advanced Science, Volume 13, Issue 5, 27 January 2026.
Chronic psychological stress activates prolactin signaling to reprogram dermal fibroblasts into APCDD1+ inflammatory effectors via NR4A1, driving midkine secretion. This paracrine hub amplifies keratinocyte proliferation and immune recruitment, thus exacerbating skin inflammation.
Zhiguo Li, Huiyi Quan, Wanting Liu, Jiaoling Chen, Mengyang Chu, Xin Tang, Ke Xue, Xuan Liu, Jingyi Ma, Yaxing Bai, Ruina Dong, Bing Li, Junfeng Hao, Wei Guo, Qingyang Li, Erle Dang, Johann E Gudjonsson, Gang Wang, Shuai Shao   +18 more
wiley   +1 more source

Transcriptomic dynamics of cardiac remodeling after myocardial infarction. [PDF]

Sci Rep
Sanjaya A.
europepmc   +1 more source

Carbon Monoxide Nanomodulator Reverses Ischemia‐Reperfusion Injury in Stroke: A Novel Dual‐Channel Therapy Mode of Co‐driving Neuroprotection and Neurogenesis

Advanced Science, Volume 13, Issue 1, 5 January 2026.
This work develops a biomimetic and reactive oxygen species‐activated carbon monoxide (CO) nanogenerator to penetrate blood‐brain barrier, arrive in stroke‐affected regions, and release CO in a controlled manner for an innovative dual‐channel therapy strategy via co‐driving neuroprotection and neurogenesis.
Xuegang Niu, Bin Gao, Hongyi Huang, Zesheng Li, Yibin Zhang, Quanlei Liu, Chao Zhang, Yang Dai, Jinkun Xu, Mingshan Liu, Yuanyuan Zhang, Yihe Wang, Penghu Wei, Yuanxiang Lin, Yongzhi Shan, Yumin Luo, Dezhi Kang, Guoguang Zhao   +17 more
wiley   +1 more source

Identification of circulating immune response-related biomarkers in patients with ANCA-associated glomerulonephritis. [PDF]

Clin Exp Med
He Y, Cao W, Hao W, Ma Y, Li Y, Ma Y, Lin L, Li W.   +7 more
europepmc   +1 more source

In Situ Assembly of Transformable Monopeptide on Activated Neutrophils Attenuates NETs‐Induced Hepatocellular Carcinoma Metastasis by Disrupting NE Nuclear Translocation

Advanced Science, Volume 13, Issue 1, 5 January 2026.
Activated neutrophils release extracellular traps (NETs) that promote tumor metastasis. FTP‐NPs are develpoed, a peptidic nanomaterial that binds NE on neutrophil membranes, forming NE‐fibril clusters that deactivate NE and prevent NETs formation. This strategy reduces metastasis and enhances the anti‐tumor immune response by targeting NE subcellular ...
Yichi Chen, Yijun Wang, Haitao Shang, Jiayue Qiu, Ruotian Zhang, Yuxiang Xiong, Tong Wang, Fengyi Wang, Anbang Wu, Xin Lin, Bolin Wu, Chen Huang, Wen Cheng, Lu Zhang   +13 more
wiley   +1 more source

NGF/BDNF-Trk/p75NTR signaling in osteosarcoma immunity: biomarkers and therapeutic opportunities. [PDF]

Front Immunol
An L, Zhuang Y, Sun H.
europepmc   +1 more source

Multifunctional Hydrogel‐Based wound Dressings for Scar‐Free Healing: Design Principles, Therapeutic Mechanisms, and Clinical Translation Challenges

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review integrates scar biology with hydrogel‐based therapeutic strategies, offering a phase‐specific framework to correlate hydrogel functions with scar‐influencing events. It highlights innovations such as stimuli‐responsive hydrogels, nanocomposite systems, and 3D‐printed scaffolds, while addressing clinical translation challenges like ...
Haonan Chai, Zhenxing Wang, Jingyi Ju, Jiaming Sun   +3 more
wiley   +1 more source