Results 221 to 230 of about 99,840 (283)

Surgical site infections and sepsis in gynecological surgery

International Journal of Gynecology &Obstetrics, Volume 172, Issue 1, Page 92-103, January 2026.
Abstract Despite advancements in infection control, surgical site infections (SSIs) and postoperative sepsis remain significant challenges in gynecological surgery, contributing to increased morbidity, mortality, and healthcare costs. In low‐income countries, circulatory failure due to septic shock leads to most deaths after surgery, with sepsis ...
Cristina Taliento, Gennaro Scutiero, Carmelia Milano, Mattia Grasso, Francesca Nitti, Orsola Brasile, Ruby Martinello, Giulia Bernardi, Stefano Restaino, Martina Arcieri, Matteo Pavone, Nicolò Bizzarri, Giuseppe Vizzielli, Pantaleo Greco   +13 more
wiley   +1 more source

Mitochondrial Dysfunction and Immune Cell Infiltration in Diabetic Kidney Disease: A Mendelian Randomization and Multiomics Study. [PDF]

Mediators Inflamm
Zhang T, Wu J, Zhang J, Hu Y, Zhao Y, Mao G, Jiao J, Wang J, Chen R, Zheng C.   +9 more
europepmc   +1 more source

The Role of Viral and Bacterial Infections in the Etiology of Behçet's Disease

Journal of Clinical Laboratory Analysis, Volume 40, Issue 1, January 2026.
Bacterial and viral pathogens may play a key role in Behçet's disease (BD) pathogenesis by triggering autoimmunity, molecular mimicry, or microbiome disruption. These infectious agents could initiate inflammatory pathways, contributing to BD's diverse clinical manifestations.
Mohsen Moghoofei, Hamid Pajavand, Razieh Shahbazi, Marzieh Rezaei, Elahe Taki   +4 more
wiley   +1 more source

Charting the expression landscape of human long non-coding RNAs across diverse biological contexts with LncExpDB 2.0. [PDF]

Nucleic Acids Res
Qi Y, Li Z, Zhou X, Wang M, Zhang Z, Ma L.   +5 more
europepmc   +1 more source

Pharmacological Inhibition of EZH2 by GSK‐343 Attenuates Neuroinflammation in a Mouse Model of Spinal Cord Injury

Journal of Neuroscience Research, Volume 104, Issue 1, January 2026.
In a mouse model of spinal cord injury, pharmacological inhibition of EZH2 with GSK‐343 reduces tissue damage and neuronal demyelination. GSK‐343 suppresses the EZH2/TRAF6/NF‐κB signaling pathway, leading to attenuation of neuroinflammation and innate immune activation. These effects promote early neuroprotection and improved locomotor recovery in vivo.
Yinhui Kang, Deborah Mannino, Valentina Bova, Alberto Repici, Bulzomì Maria, Ahmed Hasan, Antonio Catalfamo, Jia Yang, Marika Lanza, Alessia Filippone   +9 more
wiley   +1 more source

Research progress on the regulation of autophagy in cardiovascular diseases by chemokines. [PDF]

Open Life Sci
Ma J, Tan X, Feng J, Li Z, Tan S, Li B, Zhao L.   +6 more
europepmc   +1 more source

Emestrin‐Type Epidithiodiketopiperazines Inhibited Gasdermin D‐Mediated Pyroptosis via Caspase‐3/7 Activation

MedComm, Volume 7, Issue 1, January 2026.
This study demonstrates that emestrin‐type ETPs suppress GSDMD‐mediated pyroptosis through caspase‐3/7 activation, thereby attenuating inflammatory responses and conferring protection against sepsis. In THP‐1 macrophages, ETPs significantly reduced pyroptosis and secretion of the proinflammatory cytokines IL‐1β and IL‐18.
Bingchuan Geng, Shuang Lin, Wai Yen Yim, Weiguang Sun, Xiaotian Zhang, Cao Ma, Zhiwen Zhang, Quan Guo, Jie Gao, Hanxiao Zeng, Qingyi Tong, Yixuan Wang, Zhengfeng Fan, Jincheng Hou, Muwei Li, Yonghui Zhang, Zhengxi Hu   +16 more
wiley   +1 more source

CCR2 Orchestrates Preferential Homing and Therapeutic Efficacy of Gingival Mesenchymal Stem Cell‐Derived Extracellular Vesicles in Rheumatoid Arthritis

MedComm, Volume 7, Issue 1, January 2026.
CCR2 orchestrates preferential homing of GMSC‐derived extracellularvesicles to inflamed joints in rheumatoid arthritis. ABSTRACT The clinical utility of mesenchymal stem cells (MSCs) is often limited by pulmonary entrapment and poor systemic distribution, particularly in diseases constrained by physiological barriers such as rheumatoid arthritis (RA ...
Jingrong Chen, Xiao Guan, Wenbin Wu, Luyao Wu, Yan Liu, Donglan Zeng, Junlong Dang, Jun Zhao, Julie Wang, Jia Yuan, Xiaoli Fan, Yunfeng Pan, Nancy Olsen, Song Guo Zheng   +13 more
wiley   +1 more source

Pathways Contributing to Chemotherapy-Induced Myotoxicity Are Attenuated by EPA + DHA in a Clinically Relevant Model of Colorectal Cancer. [PDF]

J Cachexia Sarcopenia Muscle
Isesele PO, Bhatt BJ, Baracos VE, Damaraju S, Mazurak VC.   +4 more
europepmc   +1 more source

Betulinic Acid Eradicates Implant‐Associated Infections by Disrupting the S. aureus Biofilm Matrix and Potentiating Host Immune Clearance

Microbial Biotechnology, Volume 19, Issue 1, January 2026.
Betulinic acid reduces infection by Staphylococcus aureus biofilms on implants by inhibiting their formation and adhesion, decreasing EPS and eDNA formation and enhancing immune clearance. Simultaneously, it reduces skin tissue inflammation, enhances type I collagen production, and promotes wound healing.
Dongbin Guo, Ye Tao, Luanbiao Sun, Xinyao Liu, Yuan Gao, Peitong Jiang, Han Gao, Bingmei Wang, Li Wang   +8 more
wiley   +1 more source