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A Novel Dual Bruton's Tyrosine Kinase/Janus Kinase 3 Inhibitor Wj1113 and its Therapeutic Effects on Rheumatoid Arthritis. [PDF]

open access: yesMedComm (2020)
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Disorders of Leukocyte Chemotaxis

Pediatric Clinics of North America, 1977
The rapid accumulation of inflammatory cells at sites of microbial invasion or neoplastic transformation is a central event in immunologically-mediated host defense. The availability of methodology to accurately quantify leukocyte migration in vitro has allowed the disclosure of previously unrecognized clinical disorders, namely leukocyte dysmotility ...
Ralph Snyderman, Marilyn C. Pike
openaire   +3 more sources

Assays of Leukocyte Chemotaxis

Annual Review of Medicine, 1986
A number of disorders of leukocyte motility and chemotaxis have been reported clinically. In this paper we present a rational approach for testing cell populations for a defect in leukocyte migration and for defining the cellular basis of any abnormality observed. The principles and difficulties of individual and population-type assays are discussed.
D A Lauffenburger, S H Zigmond
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Leukocyte Chemotaxis and Pyoderma Gangrenosum

International Journal of Dermatology, 1985
Abstract: Leukocyte chemotaxis (in five patient with pyoderma gangrenosum) was studied using a modification of the Boyden chamber method. In all patients the chemotactic response was significantly lower than in the controls. This abnormal chemotaxis was a result of an intrinsic neutrophil dysfunction. No significant difference was detected between the
P. Nerella   +3 more
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