Results 241 to 250 of about 71,798 (273)
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Chemotaxis of nurse shark leukocytes
Developmental & Comparative Immunology, 1985Studies were conducted to determine the ability of leukocytes from the nurse shark to migrate in an in vitro micropore filter chemotaxis assay and to determine optimal assay conditions and suitable attractants for such an assay. A migratory response was seen with several attractants: activated rat serum, activated shark plasma, and a pool of shark ...
S. Hyder Smith, S.D. Obenauf
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Polymorphonuclear leukocyte chemotaxis in sporotrichosis
Mycopathologia, 1982A lesion of sporotrichosis shows a characteristic arrangement of the infiltrate in three zones: the central suppurative zone composed of polymorphonuclear leukocytes, the tuberculoid zone and the round cell zone. For investigating the pathomechanism of the suppurative zone formation, polymorphonuclear leukocyte chemotaxis to sporotrichin was assayed ...
Hiroshi Hachisuka +3 more
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Protein methylesterase and leukocyte chemotaxis
Molecular Immunology, 1980Abstract The involvement of protein carboxylmethylesterase in leukotaxis has been studied. The enzyme is localized in the cytosolic fraction of neutrophils. In intact cells the presence of a chemoattractant induces a rapid stimulation of enzymatic activity. An half-maximal stimulation of this activity is induced by a concentration (3 n M ) of peptide
Barbara A. Corcoran +6 more
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Chemotaxis of polymorphonuclear leukocytes
Biochemical Pharmacology, 1968Abstract Chemotaxis of polymorphonuclear leukocytes (PMN) has been studied by the use of chambers with micropore filters. This technique measures the specific, unidirectional migration of PMN toward an attractant. The nature of the medium in which the cells are suspended is important because homologous serum considerably increases cell responsiveness
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Roles of PI3Ks in leukocyte chemotaxis and phagocytosis
Current Opinion in Cell Biology, 2002Through selective disruption of phosphoinositide 3-kinase (PI3K) activity and the use of green fluorescent protein tagged derivatives of domains capable of specifically binding the lipid products of PI3Ks in vivo, it has been shown that this family of signalling enzymes have vital and distinct roles in chemotaxis, phagocytosis and phagosome maturation ...
Chris D. Ellson +2 more
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Assays of leukocyte locomotion and chemotaxis
Journal of Immunological Methods, 1998This review discusses the range of methods which are currently available for measuring locomotion and chemotaxis of leukocytes in vitro, their history, and some definitions of terms. Assays of the net migration of large cell populations, such as the filter assay are the most popular and are useful for identifying chemoattractant molecules, but give no ...
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[10] Measurement of leukocyte chemotaxis in vivo
1988Publisher Summary This chapter discusses the comparisons of the various methods and the air sac technique, which is used in the laboratory for studying early inflammatory responses to various chemotactic stimuli in mice. In examining these methods, a variety of considerations will be addressed: (l) simplicity and versatility of the method, (2 ...
Michael J. P. Lawman +3 more
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[14] Natural mediators of leukocyte chemotaxis
1988Publisher Summary This chapter discusses the natural mediators of leukocyte chemotaxis. Putative chemotactic factors must fulfill some, if not all, of the conditions. They should be present at the inflammation site to induce leukotaxis. The amount (or activity) of the chemotactic factors should be proportional to the extent of leukotaxis. They should
Mitsuo Honda +4 more
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Biologic Aspects of Leukocyte Chemotaxis [PDF]
, 1977 To protect a host against microbial invasion and the development of neoplasms, the immune system must discriminate self from nonself and then efficiently localize and eliminate material recognized as nonself. The process of localizing, degrading, and eliminating nonself can be termed an immune effector function and is largely mediated by the ...
Marilyn C. Pike, Ralph Snyderman
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Methods for Quantitation of Leukocyte Chemotaxis and Fugetaxis
2010Chemoattraction and chemorepulsion are complex directional responses of a cell to external chemotactic stimuli. The decision of a cell to move towards or away from a chemokinetic source includes detection and quantitation of the gradient of the chemotactic agent, biochemical transmission of the stimulus, and translation into a directional migration ...
VIANELLO, FABRIZIO +2 more
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