Results 251 to 260 of about 71,798 (273)
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Inhibition of PMN leukocytes chemotaxis by thalidomide
Archives of Dermatological Research, 1980The effects of thalidomide on chemotaxis of normal human peripheral blood PMN leukocytes have been studied in vitro. The chemotaxis factor was generated by interacting normal human serum with bovine gamma globulin-antibovine-gamma globulin immune complexes.
Michel Faure +2 more
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Mechanisms of leukocyte motility and chemotaxis
Current Opinion in Immunology, 1994Motility is a complex process that depends on the coordination of many cellular functions, including the conversion of information from the environment into a series of coordinated responses that culminate in directed cell movement. Major advances have been made in the understanding of many functions involved in motility, such as transmembrane ...
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Molecular and Cellular Mechanisms of Leukocyte Chemotaxis
Science, 1981The application of modern scientific methods to the study of leukocyte function has begun to reveal the molecular and cytostructural bases of the chemotactic responses of these cells. Leukocyte chemotaxis is initiated by the binding of chemoattractants to distinct plasma membrane receptors; this binding alters transmembrane potential and activates ...
Edward J. Goetzl, Ralph Snyderman
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Polymorphonuclear leukocyte chemotaxis in the absence of oxygen
Journal of Periodontal Research, 1975Human polymorphonuclear leukocytes were tested for chemotactic migration in the Boyden Chamber system. The attracting agent was activated human plasma. Experiments were carried out in a strictly anaerobic environment in which all the suspensions assumed a very low redox potential.
E. B. Kenney, J. H. Kraal
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Cellular augmentation of polymorphonuclear leukocyte chemotaxis
American Journal of Physiology-Cell Physiology, 1979The density of neutrophils influences the number of cells that will respond to a chemoattractant, endotoxin-activated serium. When fewer than 3 x 10(5) polymorphonuclear leukocytes (PMN) were placed in the top compartment of a modified Boyden chemotaxis chamber, the cellular response was weak.
R. H. Persellin, A. Takeuchi
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A Role for the Laminin Receptor in Leukocyte Chemotaxis
Journal of Leukocyte Biology, 1987Abstract Previous studies on the mechanism of leukocyte traversal of basement membranes showed that rabbit peritoneal exudate polymorphonuclear cells (PMN) preferentially used laminin, a major constituent of basement membrane, to attach to another component, type IV collagen.
E. Schiffmann +7 more
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Effects of Lithium on Polymorphonuclear Leukocyte Chemotaxis
1980Lithium, known best for its efficacy in the treatment of neuropsychiatric disorders, also is capable of influencing the function of a variety of non-neural cells. Shenkman et al. (1978), for example, demonstrated that lithium was capable of enhancing several functions of human peripheral blood mononuclear cells.
Ira M. Goldstein +4 more
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Recognition of Protein Structure in Leukocyte Chemotaxis
Nature, 1973RECOGNITION of antigen in the specific immune response is well understood. Recognition of foreign or altered self material by the cells which mediate non-specific immunity has received little attention. In tissue injury or bacterial infections, many proteins may become enzymatically degraded or conformationally altered.
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The effect of quin2 on chemotaxis by polymorphonuclear leukocytes
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 1985Exposure of rabbit polymorphonuclear leukocytes to micromolar concentrations of quin2-AM results in high intracellular concentrations of quin2, which lead to inhibition of chemotaxis. The loading efficiency of polymorphonuclear leukocytes, being the percentage of quin2-AM which is taken up by the cells and transformed intracellularly into quin2, is ...
Jan G.R. Elferink, Martha Deierkauf
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Humoral Mediators of Chemotaxis of Mononuclear Leukocytes
Journal of Infectious Diseases, 1972In-vitro studies of chemotaxis of mononuclear leukocytes (MNLs) were performed to characterize humoral mediators governing the accumulation of these cells at inflammatory sites. Two humoral factors that attract MNLs in vitro were found. The first was a heat-labile factor (mol wt, 90,000) present in untreated guinea-pig serum and plasma.
Stephan E. Mergenhagen +2 more
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