Results 251 to 260 of about 99,840 (283)
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Leukocyte Chemotaxis and Pyoderma Gangrenosum
International Journal of Dermatology, 1985Abstract: Leukocyte chemotaxis (in five patient with pyoderma gangrenosum) was studied using a modification of the Boyden chamber method. In all patients the chemotactic response was significantly lower than in the controls. This abnormal chemotaxis was a result of an intrinsic neutrophil dysfunction. No significant difference was detected between the
P. Nerella +3 more
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Chemotaxis of nurse shark leukocytes
Developmental & Comparative Immunology, 1985Studies were conducted to determine the ability of leukocytes from the nurse shark to migrate in an in vitro micropore filter chemotaxis assay and to determine optimal assay conditions and suitable attractants for such an assay. A migratory response was seen with several attractants: activated rat serum, activated shark plasma, and a pool of shark ...
S D, Obenauf, S H, Smith
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Polymorphonuclear leukocyte chemotaxis in sporotrichosis
Mycopathologia, 1982A lesion of sporotrichosis shows a characteristic arrangement of the infiltrate in three zones: the central suppurative zone composed of polymorphonuclear leukocytes, the tuberculoid zone and the round cell zone. For investigating the pathomechanism of the suppurative zone formation, polymorphonuclear leukocyte chemotaxis to sporotrichin was assayed ...
H, Hachisuka +3 more
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Protein methylesterase and leukocyte chemotaxis
Molecular Immunology, 1980Abstract The involvement of protein carboxylmethylesterase in leukotaxis has been studied. The enzyme is localized in the cytosolic fraction of neutrophils. In intact cells the presence of a chemoattractant induces a rapid stimulation of enzymatic activity. An half-maximal stimulation of this activity is induced by a concentration (3 n M ) of peptide
K, Venkatasubramanian +6 more
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Chemotaxis of polymorphonuclear leukocytes
Biochemical Pharmacology, 1968Abstract Chemotaxis of polymorphonuclear leukocytes (PMN) has been studied by the use of chambers with micropore filters. This technique measures the specific, unidirectional migration of PMN toward an attractant. The nature of the medium in which the cells are suspended is important because homologous serum considerably increases cell responsiveness
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Cellular augmentation of polymorphonuclear leukocyte chemotaxis
American Journal of Physiology-Cell Physiology, 1979The density of neutrophils influences the number of cells that will respond to a chemoattractant, endotoxin-activated serium. When fewer than 3 x 10(5) polymorphonuclear leukocytes (PMN) were placed in the top compartment of a modified Boyden chemotaxis chamber, the cellular response was weak.
A, Takeuchi, R H, Persellin
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Assays of leukocyte locomotion and chemotaxis
Journal of Immunological Methods, 1998This review discusses the range of methods which are currently available for measuring locomotion and chemotaxis of leukocytes in vitro, their history, and some definitions of terms. Assays of the net migration of large cell populations, such as the filter assay are the most popular and are useful for identifying chemoattractant molecules, but give no ...
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Inhibition of PMN leukocytes chemotaxis by thalidomide
Archives of Dermatological Research, 1980The effects of thalidomide on chemotaxis of normal human peripheral blood PMN leukocytes have been studied in vitro. The chemotaxis factor was generated by interacting normal human serum with bovine gamma globulin-antibovine-gamma globulin immune complexes.
M, Faure, J, Thivolet, M, Gaucherand
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Molecular and Cellular Mechanisms of Leukocyte Chemotaxis
Science, 1981The application of modern scientific methods to the study of leukocyte function has begun to reveal the molecular and cytostructural bases of the chemotactic responses of these cells. Leukocyte chemotaxis is initiated by the binding of chemoattractants to distinct plasma membrane receptors; this binding alters transmembrane potential and activates ...
R, Snyderman, E J, Goetzl
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Mechanisms of leukocyte motility and chemotaxis
Current Opinion in Immunology, 1994Motility is a complex process that depends on the coordination of many cellular functions, including the conversion of information from the environment into a series of coordinated responses that culminate in directed cell movement. Major advances have been made in the understanding of many functions involved in motility, such as transmembrane ...
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