Severity of experimental escherichia-coli mastitis in ketonemic and nonketonemic dairy-cows. [PDF]
, 1993 The severity of experimental Escherichia coli mastitis in relation to in vitro chemotaxis of polymorphonuclear leukocytes was investigated in cows during negative energy balance. The negative energy balance was induced by feed restriction.
Brand, A +6 more
core +1 more source
How Have Leukocyte In Vitro Chemotaxis Assays Shaped Our Ideas about Macrophage Migration?
Biology, 2020 Macrophage chemotaxis is crucial during both onset and resolution of inflammation and unique among all leukocytes. Macrophages are able to switch between amoeboid and mesenchymal migration to optimise their migration through 3D environments.
Agata N. Rumianek, David R. Greaves
doaj +1 more source
A PKC-MARCKS-PI3K regulatory module links Ca2+ and PIP3 signals at the leading edge of polarized macrophages. [PDF]
PLoS ONE, 2018 The leukocyte chemosensory pathway detects attractant gradients and directs cell migration to sites of inflammation, infection, tissue damage, and carcinogenesis.
Brian P Ziemba, Joseph J Falke
doaj +1 more source
BMC Genomics, 2022 Background Disease emergence and production loss caused by cattle tick infestations have focused attention on genetic selection strategies to breed beef cattle with increased tick resistance.
Emily F. Mantilla Valdivieso +8 more
doaj +1 more source
Genome-wide gene expression profiling of stress response in a spinal cord clip compression injury model. [PDF]
, 2013 BackgroundThe aneurysm clip impact-compression model of spinal cord injury (SCI) is a standard injury model in animals that closely mimics the primary mechanism of most human injuries: acute impact and persisting compression.
Boutros, Paul C +5 more
core +3 more sources
Conceivable difference in the anti-inflammatory mechanisms of lipocortins 1 and 5
Mediators of Inflammation, 1993 Human recombinant lipocortins (LCT) 1 and 5 have been expressed in a yeast secretion vector and purified by ion exchange chromatography. The action of the proteins has been investigated in two models of experimental acute inflammation in the rat ...
C. Becherucci +4 more
doaj +1 more source
Predicting Axonal Response to Molecular Gradients with a Computational Model of Filopodial Dynamics [PDF]
, 2004 Axons are often guided to their targets in the developing nervous system by attractive or repulsive molecular concentration gradients. We propose a computational model for gradient sensing and directed movement of the growth cone mediated by filopodia ...
Caton A. +3 more
core +3 more sources
Frontiers in Pharmacology, 2022 Neutrophils and other leukocytes invade the mouse uterus at term birth, which is normal for activating the uterus for labor. To better understand the regulation of this migration at term and interleukin (IL)-1β—induced preterm birth, we developed a mouse
Han Lee +7 more
doaj +1 more source
In vitro effects of nonesterified fatty acids on bovine neutrophils oxidative burst and viability [PDF]
, 2006 An in vitro study was conducted to examine the influence of nonesterified fatty acids (NEFA) on bovine polymorphonuclear leukocytes (PMN). Eight healthy, midlactating Holstein cows were used as blood donors.
BERNABUCCI, U +5 more
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Concepts of GPCR-controlled navigation in the immune system
, 2019 G-protein-coupled receptor (GPCR) signaling is essential for the spatiotemporal control of leukocyte dynamics during immune responses. For efficient navigation through mammalian tissues, most leukocyte types express more than one GPCR on their surface ...
Boneschansker L +26 more
core +1 more source