Results 21 to 30 of about 277,006 (294)

A new class of protein sensor links spirochete pleomorphism, persistence, and chemotaxis

open access: yesmBio, 2023
Pathogenic spirochetes can alter their morphologies and behaviors to infect and survive within their hosts. Previous reports demonstrate that the formation of the so-called “round bodies” and biofilms, and chemotaxis are involved in spirochete ...
A. R. Muok   +7 more
doaj   +1 more source

Drug targeting to decrease cardiotoxicity – determination of the cytotoxic effect of GnRH-based conjugates containing doxorubicin, daunorubicin and methotrexate on human cardiomyocytes and endothelial cells

open access: yesBeilstein Journal of Organic Chemistry, 2018
Background: Cardiomyopathy induced by the chemotherapeutic agents doxorubicin and daunorubicin is a major limiting factor for their application in cancer therapy.
Livia Polgár   +7 more
doaj   +1 more source

Metabolic products of soluble epoxide hydrolase are essential for monocyte chemotaxis to MCP-1 in vitro and in vivo

open access: yesJournal of Lipid Research, 2013
Monocyte chemoattractant protein-1 (MCP-1)-induced monocyte chemotaxis is a major event in inflammatory disease. Our prior studies have demonstrated that MCP-1-dependent chemotaxis requires release of arachidonic acid (AA) by activated cytosolic ...
Suman Kundu   +8 more
doaj   +1 more source

Chemotactic network responses to live bacteria show independence of phagocytosis from chemoreceptor sensing

open access: yeseLife, 2017
Aspects of innate immunity derive from characteristics inherent to phagocytes, including chemotaxis toward and engulfment of unicellular organisms or cell debris.
Netra Pal Meena, Alan R Kimmel
doaj   +1 more source

The Novel Protein Cj0371 Inhibits Chemotaxis of Campylobacter jejuni

open access: yesFrontiers in Microbiology, 2018
cj0371 is a novel gene that is associated with Campylobacter jejuni virulence, and an isogenic mutant of cj0371 showed hyper chemotaxis and motility. Chemotactic motility is an important virulence factor and is involved in C.
Xueqing Du   +5 more
doaj   +1 more source

A minimal model of metabolism-based chemotaxis. [PDF]

open access: yesPLoS Computational Biology, 2010
Since the pioneering work by Julius Adler in the 1960's, bacterial chemotaxis has been predominantly studied as metabolism-independent. All available simulation models of bacterial chemotaxis endorse this assumption.
Matthew D Egbert   +2 more
doaj   +1 more source

THE CHEMOSUPPRESSION OF CHEMOTAXIS [PDF]

open access: yesThe Journal of Experimental Medicine, 1966
The effects of various drugs on chemotaxis of polymorphonuclear leukocytes (PMN's) in vitro and in vivo have been studied. Response of rabbit PMN's in vitro to the chemotactic factor of rabbit serum, consisting of an activated protein-protein complex of the fifth and sixth (and probably seventh) components of complement (C'), is suppressed by ...
openaire   +3 more sources

Different migration patterns of sea urchin and mouse sperm revealed by a microfluidic chemotaxis device. [PDF]

open access: yesPLoS ONE, 2013
Chemotaxis refers to a process whereby cells move up or down a chemical gradient. Sperm chemotaxis is known to be a strategy exploited by marine invertebrates such as sea urchins to reach eggs efficiently in moving water.
Haixin Chang   +4 more
doaj   +1 more source

Mechanisms involved in human eosinophil chemotaxis induced by the newly cloned C-C chemokine eotaxin

open access: yesAllergology International, 1998
The present study was performed in order to investigate the mechanism(s) involved in eotaxin-induced normal human eosinophil chemotaxis using a 48-well micro-chemotaxis chamber assay.
Amr El-Shazly   +3 more
doaj   +1 more source

Enhancer of zeste homolog 2 enhances the migration and chemotaxis of dental mesenchymal stem cells

open access: yesJournal of International Medical Research, 2020
Objective To investigate the function of enhancer of zeste homolog 2 (EZH2) in the migration and chemotaxis of human dental tissue-derived mesenchymal stem cells. Methods The expression of EZH2, C-X-C motif chemokine ligand 11 (CXCL11), CXCL16, and CXCR1
Huarui Ma   +6 more
doaj   +1 more source

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