Results 71 to 80 of about 20,520 (283)

Ruminal methane inhibition potential of various pure compounds in comparison with garlic oil as determined with a rumen simulation technique (Rusitec) [PDF]

, 2017
Ruminants represent an important source of methane (CH4) emissions; therefore, CH4 mitigation by diet supplementation is a major goal in the current ruminant research. The objective of the present study was to use a rumen simulation technique to evaluate
Amelchanka, Sergej L., Duval, Stéphane M., Kreuzer, Michael, Soliva, Carla R.   +3 more
core  

The bile acid TGR5 membrane receptor: From basic research to clinical application [PDF]

, 2014
The TGR5 receptor (or GP-BAR1, or M-BAR) was characterized ten years ago as the first identified G-coupled protein receptor specific for bile acids.
Duboc, Henri, Hofmann, Alan F., Taché, Yvette   +2 more
core   +1 more source

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

Neurogastroenterology &Motility, EarlyView.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi, Rudolf Bauer, Thomas Efferth, Mohamed T. Khayyal, Michael Schemann, Gudrun Ulrich‐Merzenich, Christine Feinle‐Bisset   +6 more
wiley   +1 more source

The Factors of the Classification of Protein Amino Acids [PDF]

This paper is published in GLASNIK of Montenegrin Academy of Science and arts, 2000, 13, pp. 173-194, 2006
In this work it is shown that three pairs of the factors appear to be the key, i.e. main factors of a natural classification of protein (canonical) amino acids within the amino acid (genetic) code. First pair: the factors of the habit of an amino acid molecule (size and polarity).
arxiv  

Ursodeoxycholic acid, chenodeoxycholic acid, and 7-ketolithocholic acid are primary bile acids of the guinea pig.

Journal of Lipid Research, 1990
Guinea pig gallbladder bile contains chenodeoxycholic acid (62 +/- 5%), ursodeoxycholic acid (8 +/- 5%), and 7-ketolithocholic acid (30 +/- 5%). All three bile acids became labeled to the same specific activity within 30 min after [3H]cholesterol was ...
GS Tint, GR Xu, AK Batta, S Shefer, W Niemann, G Salen   +5 more
doaj  

Changing Gastrointestinal Transit Time Alters Microbiome Composition and Bile Acid Metabolism: A Cross‐Over Study in Healthy Volunteers

Neurogastroenterology &Motility, EarlyView.
Alterations in whole gut transit time (WGTT) significantly impact microbiome composition and bile acid metabolism. Using senna and loperamide, we show that WGTT changes influence bacterial diversity, bile acid profiles, and fibroblast growth factor 19, with effects reversing after 16 days—highlighting the dynamic gut‐microbiome‐bile acid interplay ...
Evette B. M. Hillman, Maximilian Baumgartner, Danielle Carson, Gregory C. A. Amos, Imad Wazir, Haider A. Khan, Malik A. Khan, Sjoerd Rijpkema, Julian R. F. Walters, Elizabeth M. H. Wellington, Ramesh Arasaradnam, Stephen J. Lewis   +11 more
wiley   +1 more source

Epimerization of chenodeoxycholic acid to ursodeoxycholic acid by human intestinal lecithinase-lipase-negative Clostridia.

Journal of Lipid Research, 1981
Six strains of lecithinase-lipase-negative Clostridia, isolated from human feces, were capable of oxidizing chenodeoxycholic acid to 3 alpha-hydroxy-7 keto-5 beta-cholanoic acid and of epimerizing it to ursodeoxycholic acid.
R Edenharder, T Knaflic
doaj  

Circular dichroism spectroscopic detection of ligand binding induced subdomain IB specific structural adjustment of human serum albumin [PDF]

, 2013
This work demonstrates for the first time that binding of various compounds within subdomain IB of human serum albumin (HSA) provokes characteristic changes in the near-UV circular dichroism (CD) spectrum of the protein.
Beaven G. H., Bertucci C., Bertucci C., Bhattacharya A. A., Brock A., Buttar D., Carter D. C., Curry S., Curry S., Datta P., Dockal M., Farruggia B., Fehske K. J., Fehske K. J., Fehske K. J., Ferenc Zsila, Ghuman J., Ishida S., Koide M., Kragh-Hansen U., Krenzel E. S., Plager J. E., Ryan A. J., Ryan A. J., Sengupta A., Shi D., Simard J. R., Sjöholm I., Strickland E. H., Sudlow G., Sudlow G., Takikawa H., Wanwimolruk S., Zhu L., Zsila F., Zsila F., Zunszain P. A., Zunszain P. A.   +37 more
core   +1 more source

Impacts of Vincristine and Prednisolone Chemotherapy on the Canine Gut Microbiota in Dogs Undergoing Treatment for Lymphoma

Veterinary and Comparative Oncology, EarlyView.
ABSTRACT Chemotherapy can have adverse gastrointestinal effects in dogs and people. The objective of this study was to assess the impact of vincristine and prednisolone/prednisone, as part of a CHOP chemotherapy [cyclophosphamide, hydroxydaunorubicin, oncovin (vincristine) and prednisolone/prednisone] protocol, on gastrointestinal dysbiosis in dogs ...
Juan Aragon, Annika M. Weber, Madison Tipton, Jennifer Thomsen, Hend Ibrahim, Kristen Weishaar, Sangeeta Rao, Jan S. Suchodolski, Jonathan Stockman, Elizabeth P. Ryan, Nora Jean Nealon   +10 more
wiley   +1 more source

Modeling of the formation of short-chain acids in propane flames [PDF]

arXiv, 2009
In order to better understand their potential formation in combustion systems, a detailed kinetic mechanism for the formation of short-chain monocarboxylic acids, formic (HCOOH), acetic (CH3COOH), propionic (C2H5COOH) and propenic (C2H3COOH)) acids, has been developed. Simulations of lean (equivalence ratios from 0.9 to 0.48) laminar premixed flames of
arxiv