Results 101 to 110 of about 459,773 (306)
Advanced Science, EarlyView.ABSTRACT Accumulating evidence suggests that the intestinal microbiota participates in the progression of metabolic dysfunction‐associated steatotic liver disease (MASLD) through microbiota‐host interaction. However, the beneficial role of commensal mycobiota in MASLD progression remains poorly understood.
Shuping Qiao +11 more
wiley +1 more source
ChIP-Seq analysis of the divergent promoter for acrAB-nodT and tipR.
, 2023 (A) Representation of the reads (in reads per million (RPM)) obtained from the ChIP-Seq analyses covering the TipR binding regions. Positions are indicated under the graphic.
Bastien Casu (3935507) +6 more
core +1 more source
Androgen receptor DNA binding and chromatin accessibility profiling in prostate cancer
Genomics Data, 2016 Prostate cancer (PCa) is the second most common cancer in men. The Androgen Receptor (AR) is the major driver of PCa and the main target of therapy in the advanced setting.
Ekaterina Nevedomskaya +6 more
doaj +1 more source
A Rare Allele of ST5 From Wild Rice Enhances Salt Tolerance in Rice
Advanced Science, EarlyView.A novel salt‐tolerance gene ST5W, characterized by a unique 36‐bp promoter insertion, is found exclusively in a small subset of Oryza rufipogon and is absent in cultivated rice. Field trials confirm ST5W significantly enhances rice yield across diverse genetic backgrounds under saline conditions.
Meng Xing +26 more
wiley +1 more source
ChIP-seq reveals extensive NF90/NF110 occupancy along the genome.
, 2018 (a) ChIP-seq signal (fold enrichment over input) of NF90/NF110 shown along chromosome one, along peaks called using Irreproducibility Discovery Rate (IDR) between biological replicates. UCSC known genes and transcripts are aligned.
Minyi Shi (179103) +6 more
core +1 more source
TAF-ChIP: an ultra-low input approach for genome-wide chromatin immunoprecipitation assay
Life Science Alliance, 2019 The authors present a novel method for obtaining chromatin profiles from low cell numbers without prior nuclei isolation. The method is successfully implemented in generating epigenetic profile from 100 cells with high signal-to-noise ratio.
Junaid Akhtar +10 more
doaj +1 more source
Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain
Advanced Science, EarlyView.This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao +7 more
wiley +1 more source
, 2021 The Quick Files feature was discontinued and it’s files were migrated into this Project on March 11, 2022. The file URL’s will still resolve properly, and the Quick Files logs are available in the Project’s Recent ...
Chip Seq
core +2 more sources
Bio-Protocol, 2017 Chromatin immunoprecipitation followed by massively parallel sequencing (ChIP-seq) is a powerful technology to profile genome-wide chromatin modification patterns and is increasingly being used to study the molecular mechanisms of brain diseases such as ...
Yong-Hwee Loh +3 more
doaj +1 more source
Advanced Science, EarlyView.ABSTRACT Inflammatory bowel disease (IBD) is characterized by dysregulated T cell responses. RNA helicases, including DExD‐box helicase 21 (DDX21), are pivotal in RNA metabolism, but their role in T cell‐mediated pathology during IBD remains unclear. Here, we demonstrate that DDX21 expression in CD4+ T cells correlates with cell cycle and translation ...
Yujuan Zhang +11 more
wiley +1 more source