Results 191 to 200 of about 928,240 (334)

Analyzing histone ChIP-seq data with a bin-based probability of being signal. [PDF]

PLoS Comput Biol, 2023
Hecht V, Dong K, Rajesh S, Shpilker P, Wekhande S, Shoresh N.   +5 more
europepmc   +1 more source

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

An MNase-ChIP-Seq Protocol to Profile Histone Modifications at a DNA Break in Yeast. [PDF]

Methods Protoc
Di Nisio E, Frigerio C, Licursi V, Castelli S, Caraba B, Negri R, Clerici M.   +6 more
europepmc   +1 more source

Validating a re-implementation of an algorithm to integrate transcriptome and ChIP-seq data. [PDF]

PeerJ, 2023
Ahmed M, Kim DR.
europepmc   +1 more source

Proton FLASH Exposure Preserves Gut Commensal Microbiomes and Spares Intestinal Stem Cells

Advanced Science, EarlyView.
This study highlights the role of Proton FLASH abdominal irradiation in sparing of intestinal stem cells and preservation of key gut microbial population resulting minimization of radiation toxicity in intestinal epithelium in mice. Our findings support the potential of Proton FLASH to improve the therapeutic ratio for abdominal radiation exposure ...
Rishi Man Chugh, Payel Bhanja, Emily Schueddig, Jufri Setianegara, Yuting Lin, Kenny Guida, Shujah Rehman, Stacey Krepel, Devin Koestler, Ronald C. Chen, Katherine L. Cook, Subhrajit Saha   +11 more
wiley   +1 more source

Automated chromatin profiling with spa-ChIP-seq uncovers the impacts of condition variations. [PDF]

Genome Res
Cao Y, Patel L, Alcoser L, Mendenhall E, Benner C, Heinz S, Goren A.   +6 more
europepmc   +1 more source

Motif elucidation in ChIP-seq datasets with a knockout control. [PDF]

Bioinform Adv, 2023
Denisko D, Viner C, Hoffman MM.
europepmc   +1 more source

Myeloid‐Derived Grancalcin Promotes Periodontal Inflammation and Pathological Bone Remodeling in Periodontitis

Advanced Science, EarlyView.
Grancalcin (GCA), a myeloid‐derived protein, is enriched in gingival tissues of periodontitis patients and mouse models. Through interactions with CD44 and activation of MYH9, GCA promotes NF‐κB signaling and exacerbates periodontal inflammation and bone loss.
Min Zhou, Yao Xiao, Ziyue Xu, Chengyu Yang, Jiang Li, Ya Liu, Ping Yin   +6 more
wiley   +1 more source

CHIP-seq and transcriptomics reveal a new role of circadian-regulated StBBX24 protein in potato reproduction. [PDF]

BMC Plant Biol
Grądzka K, Biegańska M, Koczyk G, Młodzińska A, Pawłowicz I, Kiełbowicz-Matuk A.   +5 more
europepmc   +1 more source

Combating VEGFA‐siRNA‐Induced Metabolic Reprogramming via Glucose Utilization Deprivation

Advanced Science, EarlyView.
An ionizable lipid nanoparticle co‐delivers VEGFA siRNA and glucose oxidase to tumors to counteract VEGFA knockdown‐induced, glutamine‐driven metabolic compensation. Enzymatic glucose consumption reverses the adaptive pathways and restores metabolism toward baseline, thereby sensitizing tumors to therapy.
Lulu Zheng, Shuai Guo, Yingjixing Luo, Pengfei Wu, Haiyin Yang, Yingqiu Xie, Yuchuan Fan, Qing Liu, Bo Hu, Jia Huang, Yuanyu Huang   +10 more
wiley   +1 more source