Chiral Phosphoric Acid Promoted Chiral 1H NMR Analysis of Atropisomeric Quinolines [PDF]
Frontiers in Chemistry, 2021 An efficient enantioselective NMR analysis of atropisomeric quinolines in the promotion of chiral phosphoric acid is described, in which a variety of racemic 4-aryl quinolines were well-recognized with up to 0.17 ppm ΔΔδ value.
Junlin Wan, Jun Jiang, Juan Li
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Chiral phosphoric acid-catalyzed asymmetric synthesis of helically chiral, planarly chiral and inherently chiral molecules [PDF]
Beilstein Journal of Organic ChemistryChiral molecules, distinguished by nonsuperimposability with their mirror image, play crucial roles across diverse research fields. Molecular chirality is conventionally categorized into the following types: central chirality, axial chirality, planar ...
Wei Liu, Xiaoyu Yang
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Chiral phosphoric acid-catalyzed stereodivergent synthesis of trisubstituted allenes and computational mechanistic studies [PDF]
Nature Communications, 2020 Despite of the high demand of chiral allenes, their asymmetric synthesis remains a challenge for organic chemists. Here, the authors report a stereodivergent synthesis of trisubstituted allenes via asymmetric additions of oxazolones to activated 1,3 ...
Jiawen Wang +6 more
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Chiral phosphoric acid-catalyzed asymmetric epoxidation of alkenyl aza-heteroarenes using hydrogen peroxide [PDF]
Nature CommunicationsThe synthesis of chiral α-azaheteroaryl oxiranes via enantioselective catalysis is a formidable challenge due to the required complex stereoselectivity and diverse N-heterocyclic structures.
Hao-Chen Wen +9 more
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Phosphoric acid-catalyzed atroposelective construction of axially chiral arylpyrroles [PDF]
Nature Communications, 2019 Axially chiral arylpyrroles are structural motifs often found in natural and medicinal products. Here, the authors report the atroposelective synthesis of axially chiral arylpyrrole derivatives, which proved to be efficient chiral ligands for asymmetric ...
Lei Zhang +5 more
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Chiral phosphoric acid-catalyzed atroposelective iodination of N-arylindoles [PDF]
Communications ChemistryAxially chiral indoles have garnered significant attention due to their synthetic and biological importance. However, atroposelective halogenation of this scaffold has been rarely explored.
Ahreum Kim +4 more
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Stereoselective Biginelli-like reaction catalyzed by a chiral phosphoric acid bearing two hydroxy groups [PDF]
Beilstein Journal of Organic Chemistry, 2020 To develop new efficient stereoselective catalysts for Biginelli-like reactions, a chiral phosphoric acid bearing two hydroxy groups derived from ʟ-tartaric acid was successfully synthesized via highly regioselective transformations of enantiopure 1,1,4 ...
Xiaoyun Hu +4 more
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Chiral phosphoric acid-catalyzed enantioselective phosphinylation of 3,4-dihydroisoquinolines with diarylphosphine oxides [PDF]
Communications Chemistry, 2023 Catalytic enantioselective phosphinylation of imines with diarylphosphine oxides is a powerful approach to access chiral α-amino diarylphosphine oxides.
Yongbiao Guo +6 more
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Atroposelective Synthesis of Biaryl Diamines and Amino Alcohols via Chiral Phosphoric Acid Catalyzed para-Aminations of Anilines and Phenols [PDF]
iScience, 2019 Summary: A versatile method for atroposelective synthesis of chiral biaryl diamines and amino alcohols has been developed via para-amination of anilines and phenols with azodicarboxylates enabled by chiral phosphoric acid catalysis.
Donglei Wang +4 more
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Chiral 1H NMR of Atropisomeric Quinazolinones With Enantiopure Phosphoric Acids [PDF]
Frontiers in Chemistry, 2018 A chiral phosphoric acid promoted enantioselective NMR analysis of atropisomeric quinazolinones was described, in which a variety of racemic arylquinazolinones such as afloqualone and IC-87114 were well recognized with up to 0. 21 ppm ΔΔδ value.
Chaofei Wu +5 more
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