Results 11 to 20 of about 10,800 (238)
Chiral phosphoric acid-catalyzed transfer hydrogenation of 3,3-difluoro-3H-indoles [PDF]
Beilstein Journal of Organic ChemistryA convenient and efficient method for the synthesis of optically active difluoro-substituted indoline derivatives starting from the corresponding 3H-indoles by chiral phosphoric acid-catalyzed transfer hydrogenation was developed. Using Hantzsch ester as
Yumei Wang +3 more
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Chiral phosphoric acid catalyzed aminative dearomatization of α-naphthols/Michael addition sequence [PDF]
Nature Communications, 2019 Catalytic asymmetric dearomatization (CADA) reactions readily convert common aromatic compounds to diverse 3D chiral, polycyclic molecules. Here, the authors report an intermolecular asymmetric dearomatization of nucleophile-tethered α-naphthols ...
Zi-Lei Xia +3 more
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Chiral phosphoric acid and its applications of asymmetric catalytic hydrogenation [PDF]
E3S Web of Conferences, 2021 As an excellent representative of organic small molecular catalysts, chiral phosphoric acid played an important role in asymmetric catalytic hydrogenation.
Zhuoxin Sun
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Recent advances in the asymmetric phosphoric acid-catalyzed synthesis of axially chiral compounds
Beilstein Journal of Organic Chemistry, 2021 In recent years, the synthesis of axially chiral compounds has received considerable attention due to their extensive application as biologically active compounds in medicinal chemistry and as chiral ligands in asymmetric catalysis.
Alemayehu Gashaw Woldegiorgis +1 more
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Stereoselective Synthesis of Axially Chiral Allenes and Styrenes via Chiral Phosphoric Acid Catalysis: An Overview [PDF]
ACS OmegaAlemayehu Gashaw Woldegiorgis +5 more
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Chiral Phosphoric Acid Catalyzed Peroxidation of Imines [PDF]
Angewandte Chemie International Edition, 2010 Peroxide-containing compounds are a class of biologically important targets, many of which possess antitumor, anti-bacterial, and antimalarial activities.[1] For example, the peroxide-containing natural product artemisinin (qinghaosu) has been shown to be a highly effective antimalarial drug.[2] The chiral peroxide moiety in this natural product was ...
Wenhua, Zheng +2 more
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Nature Communications, 2022 There is great interest in methods for catalytic enantioselective construction of axially chiral compounds found in natural products. Here, the authors develop a cycloaddition strategy for atroposelective construction of indole-based biaryls via chiral ...
Hui Yang +8 more
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Chiral Phosphoric Acid Catalysis: The Terada Model Revisited [PDF]
The Journal of Organic Chemistry, 2021 Since Akiyama and Terada independently reported the introduction of chiral phosphoric acids (CPAs) as effective catalysts for Mannich-type reactions in 2004, the field of CPA catalysis has grown immensely. Terada reported in 2008 the first example of the activation of aldehydes by a CPA.
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Nature Communications, 2021 Although the hetero-Diels–Alder reaction is a staple of organic chemistry, catalytic asymmetric versions of the inverse-electron demand variant often require specially engineered substrates for the reaction to work. Here the authors cyclize non-activated
Min Jin +10 more
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Hydrazones as Singular Reagents in Asymmetric Organocatalysis [PDF]
, 2016 This Minireview summarizes strategies and developments regarding the use of hydrazones as reagents in asymmetric organocatalysis, their distinct roles in nucleophile–electrophile, cycloaddition, and cyclization reactions.
Fernández Fernández, Rosario Fátima +4 more
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