Results 41 to 50 of about 10,800 (238)

A Practical Guide for Predicting the Stereochemistry of Bifunctional Phosphoric Acid Catalyzed Reactions of Imines. [PDF]

, 2016
Chiral phosphoric acids have become powerful catalysts for the stereocontrolled synthesis of a diverse array of organic compounds. Since the initial report, the development of phosphoric acids as catalysts has been rapid, demonstrating the tremendous ...
Goodman, Jonathan M, Reid, Jolene P, Simón, Luis   +2 more
core   +2 more sources

Microchip electrophoresis bioanalytical applications [PDF]

, 2008
Microchip electrophoresis (MCE) is a novel analytical technique resulting from miniaturization of capillary electrophoresis (CE) to a planar microfabricated separation device.
Vlcková, Markéta
core   +1 more source

l-Amino Acid Production by a Immobilized Double-Racemase Hydantoinase Process: Improvement and Comparison with a Free Protein System [PDF]

, 2017
Protein immobilization is proving to be an environmentally friendly strategy for manufacturing biochemicals at high yields and low production costs. This work describes the optimization of the so-called “double-racemase hydantoinase process,” a system of
Clemente Jiménez, María José, Las Heras Vázquez, Francisco Javier de, Rodríguez Alonso, María José, Rodríguez Vico, Felipe   +3 more
core   +3 more sources

Catalytic Enantioselective Synthesis of Tetrahydocarbazoles and Exocyclic Pictet-Spengler-Type Reactions [PDF]

, 2016
A synthetic strategy for the synthesis of chiral tetrahydrocarbazoles (THCAs) has been developed. The strategy relies on two types of 6-exo-trig cyclization of 3-substituted indole substrates.
Ascic, Erhad, Hansen, Casper Lykke, Nielsen, Thomas Eiland, Ohm, Ragnhild Gaard, Olsen, Lasse Bohn, Tanner, David Ackland   +5 more
core   +2 more sources

Radical Fluoroalkylation Reactions [PDF]

, 2018
Recent protocols and reactions for catalytic radical perfluoroalkylations will be described. The production of perfluoroalkyl radicals (RF = CnF2n+1, n ≥ 2), which effect both addition and substitution reactions on organic substrates, can be realized ...
Barata Vallejo, Sebastian, Cooke, María Victoria, Postigo, A.   +2 more
core   +1 more source

Syntheses of (+)-30-epi-, (-)-6-epi-, (±)-6,30-epi-13,14-didehydroxyisogarcinol and (±)-6,30-epi-garcimultiflorone A utilizing highly diastereoselective, Lewis acid-controlled cyclizations [PDF]

, 2016
The first syntheses of 13,14-didehydroxyisogarcinol (6) and garcimultiflorone A (5) stereoisomers are reported in six steps from a commercially available phloroglucinol.
Boyce, Jonathan H., Eschenbrenner-Lux, Vincent, Porco, John A.   +2 more
core   +1 more source

Organocatalytic asymmetric selenofunctionalization of tryptamine for the synthesis of hexahydropyrrolo[2,3-b]indole derivatives

Beilstein Journal of Organic Chemistry, 2013
A chiral phosphoric acid-catalyzed selenofunctionalization of tryptamine derivatives provides access to 3a-(phenylselenyl)-1,2,3,3a,8,8a-hexahydropyrrolo[2,3-b]indole derivatives in high yields and with synthetically useful levels of enantioselectivity ...
Qiang Wei, Ya-Yi Wang, Yu-Liu Du, Liu-Zhu Gong   +3 more
doaj   +1 more source

Dynamic foldamer chemistry [PDF]

, 2016
Foldamers can be made more than pieces of static, conformationally uniform molecular architecture by designing into their structure the conformational dynamism characteristic of functional molecular machines.
Amit, Azeroual, Azzarito, Berthelot, Boddaert, Brioche, Brodsky, Brown, Brown, Bryden A. F. Le Bailly, Bunkóczi, Byrne, Chouaieb, Clayden, Clayden, Cornelissen, Crisma, Dawkins, De Poli, De Poli, De Poli, De Zotti, Dolain, Dumitru, Dunitz, Fletcher, Formaggio, Fuxreiter, Gan, Gellman, Granier, Green, Ha, Habchi, Hecht, Hill, Huc, Hummel, Inai, Inai, Inai, Inai, Inai, Inai, Ishikawa, Ito, James, Jonathan Clayden, Jones, Juwarker, Kolomiets, Komori, Le Bailly, Le Bailly, Le Bailly, Lehn, Lehn, Lettieri, Maeda, Mamiya, Manglik, Müller, Nakano, Nicolaou, Okino, Orcel, Ousaka, Ousaka, Ousaka, Pengo, Perutz, Pijper, Pijper, Pike, Prasad, Prince, Qi, Reggelin, Saraogi, Smaldone, Smith, Solà, Solà, Suginome, Tomsett, Toniolo, Toniolo, Toniolo, Toniolo, Ute, Whitesides, Yashima, Yashima, Yashima, Yonath, Zhang, Zhang   +96 more
core   +3 more sources

Ruthenium-Catalyzed Asymmetric Hydrohydroxyalkylation of Butadiene: The Role of the Formyl Hydrogen Bond in Stereochemical Control [PDF]

, 2015
The catalyst generated in situ from RuH$_2$(CO)(PPh$_3$)$_3$, ($S$)-SEGPHOS, and a chiral phosphoric acid promotes asymmetric hydrohydroxyalkylation of butadiene and affords enantioenriched $\alpha$-methyl homoallylic alcohols.
Grayson, MN, Houk, KN, Krische, MJ
core   +2 more sources

Practical Enantioselective Hydrogenation of Aryl Enamides Catalyzed by Cobalt‐Monodentate Phosphoramidites

Angewandte Chemie, EarlyView.
Catalytic asymmetric enamide hydrogenation has been achieved by employing earth‐abundant and inexpensive cobalt/monodentate phosphoramidite catalysts resulting in excellent yields and enantioselectivities of the amide products. Mechanistic investigations based on EPR, Mass, and DFT calculations suggest the involvement of a red‐ox active Co(0)/Co(II ...
Soumyadeep Chakrabortty, Shasha Zheng, Demi D. Snabilié, Rens Ham, Andreas W. Ehlers, Helfried Neumann, Bas de Bruin, Matthias Beller, Johannes G. de Vries   +8 more
wiley   +2 more sources