Results 11 to 20 of about 3,359,139 (307)
Frontiers in Neuroscience, 2021 AimGtACR2, a light-activated chloride channel, is an attractive tool for neural inhibition as it can shunt membrane depolarizations. In this study, we assessed the effect of activating GtACR2 on in vivo hippocampal CA1 activity evoked by Schaffer ...
Anirudh R. Acharya +8 more
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Chloride channels in stroke [PDF]
Acta Pharmacologica Sinica, 2012 Vascular remodeling of cerebral arterioles, including proliferation, migration, and apoptosis of vascular smooth muscle cells (VSMCs), is the major cause of changes in the cross-sectional area and diameter of the arteries and sudden interruption of blood flow or hemorrhage in the brain, ie, stroke.
Ya-ping, Zhang +2 more
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Functional architecture of the CFTR chloride channel
Molecular Membrane Biology, 2014 Paul Linsdell
exaly +2 more sources
Proton-Activated Chloride Channel: Physiology and Disease
Frontiers in Bioscience-Landmark, 2023 The maintenance of intracellular and extracellular pH relies on multiple ion transporters/channels. Proton-activated chloride channel (PAC) precisely regulates extracellular and early/late endosomal pH by transporting chloride ion (Cl-) across membranes ...
Fanglin Peng +3 more
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Cryo-EM structure of a proton-activated chloride channel TMEM206
Science Advances, 2020 Cryo-EM reveals structural insights into a new class of chloride channels that underlies acid-sensitive anion currents. TMEM206 has been recently identified as an evolutionarily conserved chloride channel that underlies ubiquitously expressed, proton ...
Z. Deng +8 more
semanticscholar +1 more source
Osmoregulated Chloride Currents in Hemocytes from Mytilus galloprovincialis. [PDF]
PLoS ONE, 2016 We investigated the biophysical properties of the transport mediated by ion channels in hemocytes from the hemolymph of the bivalve Mytilus galloprovincialis.
Monica Bregante +6 more
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Impact of chloride channel on firing patterns of the fractional-order Morris–Lecar model
Results in Applied Mathematics, 2022 Fractional calculus as a new approach for modeling has been used widely to study the non-linear behavior of physical and biological systems with some degrees of fractionality or fractality using differential and integral operators with non integer-orders.
Tahmineh Azizi
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Structural and Biophysical Analysis of the CLCA1 VWA Domain Suggests Mode of TMEM16A Engagement
Cell Reports, 2020 Summary: The secreted protein calcium-activated chloride channel regulator 1 (CLCA1) utilizes a von Willebrand factor type A (VWA) domain to bind to and potentiate the calcium-activated chloride channel TMEM16A.
Kayla N. Berry, Tom J. Brett
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Molecular mechanisms of Cys-loop ion channel receptor modulation by ivermectin
Frontiers in Molecular Neuroscience, 2012 Ivermectin is a gold standard anthelmintic drug that works by potently depressing neuronal activity and muscular contractility in arthropods and nematodes. At the molecular level, ivermectin activates inhibitory glutamate-gated chloride channels (GluClRs)
Timothy eLynagh, Joe eLynch
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Chloride – The Underrated Ion in Nociceptors
Frontiers in Neuroscience, 2020 In contrast to pain processing neurons in the spinal cord, where the importance of chloride conductances is already well established, chloride homeostasis in primary afferent neurons has received less attention.
Bettina U. Wilke +3 more
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