Results 31 to 40 of about 326,511 (299)
Dynamic change of electrostatic field in TMEM16F permeation pathway shifts its ion selectivity. [PDF]
, 2019 TMEM16F is activated by elevated intracellular Ca2+, and functions as a small-conductance ion channel and as a phospholipid scramblase. In contrast to its paralogs, the TMEM16A/B calcium-activated chloride channels, mouse TMEM16F has been reported as a ...
Han, Tina W +4 more
core +2 more sources
Role of physiological ClC-1 Cl- ion channel regulation for the excitability and function of working skeletal muscle. [PDF]
, 2016 Electrical membrane properties of skeletal muscle fibers have been thoroughly studied over the last five to six decades. This has shown that muscle fibers from a wide range of species, including fish, amphibians, reptiles, birds, and mammals, are all ...
Chen, Tsung-Yu +4 more
core +1 more source
Splicing of human chloride channel 1
Biochemistry and Biophysics Reports, 2016 Expression of chloride channel 1 (CLCN1/ClC-1) in skeletal muscle is driven by alternative splicing, a process regulated in part by RNA-binding protein families MBNL and CELF.
Takumi Nakamura +6 more
doaj +1 more source
Chloride channels and the reactions of cells to topography [PDF]
European Cells & Materials, 2001 The reactions of rat epitenon cells to substratum topography on the micrometric and nanometric scale such as groove-ridge structures include cell extension, elongation and orientation reactions.
G Tobasnick, ASG Curtis
doaj +1 more source
Glutamate-gated Chloride Channels [PDF]
Journal of Biological Chemistry, 2012 Glutamate-gated chloride channels (GluCls) are found only in protostome invertebrate phyla but are closely related to mammalian glycine receptors. They have a number of roles in these animals, controlling locomotion and feeding and mediating sensory inputs into behavior.
openaire +2 more sources
Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis [PDF]
, 2014 CFTR is a dynamically regulated anion channel. Intracellular WNK1-SPAK activation causes CFTR to change permeability and conductance characteristics from a chloride-preferring to bicarbonate-preferring channel through unknown mechanisms.
Alkaade, Samer +26 more
core +4 more sources
eLife, 2018 Light-gated chloride channels are emerging as promising optogenetic tools for inhibition of neural activity. However, their effects depend on the transmembrane chloride electrochemical gradient and may be complex due to the heterogeneity of this gradient
Jessica E Messier +3 more
doaj +1 more source
Claudins in the Renal Collecting Duct [PDF]
, 2019 The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis.
Leiz, Janna, Schmitt-Ott, Kai M.
core +1 more source
Reusable Ionogel-based Photo-actuators in a Lab-on-a-disc [PDF]
, 2017 This paper describes the design, fabrication and performance of a reusable ionogel-based photo-actuator, in-situ photopolymerised into a lab-on-a-disc microfluidic device, for flow control.
Benito López, Fernando +6 more
core +2 more sources
Frontiers in Pharmacology, 2018 The mutation F508del, responsible for a majority of cystic fibrosis cases, provokes the instability and misfolding of the CFTR chloride channel. Pharmacological recovery of F508del-CFTR may be obtained with small molecules called correctors.
Emanuela Pesce +16 more
doaj +1 more source