Lactate-proton co-transport and its contribution to interstitial acidification during hypoxia in isolated rat spinal roots [PDF]
Exposure of nervous tissue to hypoxia results in interstitial acidification. There is evidence for concomitant decrease in extracellular pH to the increase in tissue lactate.
Aronson +45 more
core +1 more source
A Multidomain Model for Ionic Electrodiffusion and Osmosis with an Application to Cortical Spreading Depression [PDF]
Ionic electrodiffusion and osmotic water flow are central processes in many physiological systems. We formulate a system of partial differential equations that governs ion movement and water flow in biological tissue.
Mori, Yoichiro
core
ST-Producing E. coli Oppose Carcinogen-Induced Colorectal Tumorigenesis in Mice. [PDF]
There is a geographic inequality in the incidence of colorectal cancer, lowest in developing countries, and greatest in developed countries.
Li, Peng +3 more
core +2 more sources
A Mathematical Model of Lysosomal Ion Homeostasis Points to Differential Effects of Cl- Transport in Ca2+ Dynamics [PDF]
The establishment and maintenance of ion gradients between the interior of lysosomes and the cytosol are crucial for numerous cellular and organismal functions.
Astaburuaga, Rosario +3 more
core +1 more source
Regulation of chloride homeostasis in plants by nitrate availability
No
Romero-Jiménez, David +4 more
openaire +2 more sources
Current view on the functional regulation of the neuronal K+-Cl- cotransporter KCC2
In the mammalian central nervous system, the inhibitory strength of chloride (Cl-)-permeable GABAA and glycine receptors (GABAAR and GlyR) depends on the intracellular Cl- concentration ([Cl-]i).
Igor eMedina +13 more
doaj +1 more source
Management of hyperkalemia in the acutely ill patient. [PDF]
PURPOSE:To review the mechanisms of action, expected efficacy and side effects of strategies to control hyperkalemia in acutely ill patients. METHODS:We searched MEDLINE and EMBASE for relevant papers published in English between Jan 1, 1938, and July 1,
Dépret, François +5 more
core +3 more sources
BackgroundTraumatic brain injury (TBI) is a major cause of disabilities in industrialized countries. Cognitive decline typically occurs in the chronic phase of the condition, following cellular and molecular processes. In this study, we described the use
L. Caccialupi Da Prato +8 more
doaj +1 more source
Consequences of cystic fibrosis transmembrane regulator mutations on inflammatory cells [PDF]
Recent studies in cystic fibrosis (CF) transmembrane regulator (CFTR) mutations and function have shed light on its involvement in disease progression. The extent of cell and tissue distribution of CFTR facilitates systemic dysfunction of ion transport ...
Castro, Guillermo Raul +2 more
core +1 more source
The establishment and maintenance of ion gradients between the interior of lysosomes and the cytosol are crucial for numerous cellular and organismal functions.
Rosario Astaburuaga +3 more
doaj +1 more source

