Results 121 to 130 of about 839,045 (255)

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

Importance of chloride homeostasis in the operation of rhythmic motor networks

, 2011
GABA and glycine are classically called "inhibitory" amino acids, despite the fact that their action can rapidly switch from inhibition to excitation and vice versa. The postsynaptic action depends on the intracellular concentration of chloride ions ([Cl À ] i), which is regulated by proteins in the plasma membrane: the K þ-Cl À cotransporter KCC2 and ...
Viemari, Jean-Charles, Bos, Rémi, Boulenguez, Pascale, Brocard, Cécile, Brocard, Frédéric, Bras, Hélène, Coulon, Patrice, Liabeuf, Sylvie, Pearlstein, Edouard, Sadlaoud, Karina, Stil, Aurélie, Tazerart, Sabrina, Vinay, Laurent   +12 more
openaire   +3 more sources

Significance of the concentration of chloride in the repair of concrete highway structures using surface applied corrosion inhibitors [PDF]

, 2005
Presented at the first International Conference on Concrete Repair, Rehabilitation and Retrofitting (ICCRRR 2005), Cape Town, South Africa, 21-23 November, 2005Advances in surface-applied corrosion inhibitors suggest that they have the potential to ...
Richardson, Mark G., Grimes, E., Söylev, T. A., McNally, Ciaran   +3 more
core   +1 more source

Monitoring Changes in Intracellular Chloride Levels Using the FRET-Based SuperClomeleon Sensor in Organotypic Hippocampal Slices

Bio-Protocol
The reduction in intracellular neuronal chloride concentration is a crucial event during neurodevelopment that shifts GABAergic signaling from depolarizing to hyperpolarizing.
Sam de Kater, Lotte Herstel, Corette Wierenga   +2 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

Advanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan, Litao Wang, Tuuli‐Marjaana Koski, Lizhe An, Thomas Efferth, Yujie Fu   +5 more
wiley   +1 more source

Daily rhythm in cortical chloride homeostasis underpins functional changes in visual cortex excitability. [PDF]

Nat Commun, 2023
Pracucci E, Graham RT, Alberio L, Nardi G, Cozzolino O, Pillai V, Pasquini G, Saieva L, Walsh D, Landi S, Zhang J, Trevelyan AJ, Ratto GM.   +12 more
europepmc   +1 more source

Gut Microbiota‐Isoallolithocholic Acid Crosstalk Promotes Calcium Oxalate Kidney Stone Formation via PARP1‐Mediated Parthanatos

Advanced Science, EarlyView.
ABSTRACT Bile acids have been implicated in calcium oxalate (CaOx) nephrolithiasis. Here, we employ multi‐omics approaches to identify isoallolithocholic acid (isoalloLCA) as the key bile acid elevated in the feces, serum, kidney, and urine of CaOx rats, confirmed by spatial metabolomics.
Zijian Zhou, Ruixi Yu, Xuan Zhou, Feng Shi, Zeyu Lin, Peng Gao, Lujia Wang, Ninghan Feng, Zhong Wu, Dawei Wang   +9 more
wiley   +1 more source

Lifetime performance characteristics of screen-printed potentiometric Ag/AgCl chloride sensors

, 2010
Ag/AgCl chloride sensors were fabricated using thick-film technology. A number of different formulations were prepared and chloride responses were investigated over time.
Lewis, Adam, Nie, Menyang, Wharton, Julian, Cranny, Andrew, Harris, Nick, Wood, Robert, Stokes, Keith   +6 more
core   +1 more source

Puzzle resolved: CFTR mediates chloride homeostasis by segregating absorption and secretion to different cell types. [PDF]

J Clin Invest, 2023
Tümmler B.
europepmc   +1 more source

Nano Proton Scavengers Modulate Endosomal pH to Inhibit Microglial Activation and Enhance Stroke Recovery

Advanced Science, EarlyView.
Amphiphilic sulfonated chitosan nanoparticles buffer endo/lysosomal acidity in microglia by limiting V‐ATPase membrane recruitment and restoring endosomal homeostasis. Following systemic administration, they accumulate in the ischemic hemisphere partly through association with infiltrating immune cells, suppress TLR3/IRF3 and TLR4/NF‐κB signaling ...
Xuanlin Wang, Yujing Shi, Zehua Gao, Jing Wang, Changsheng Liu   +4 more
wiley   +1 more source