Results 91 to 100 of about 296,529 (174)

Chloride Homeostasis Regulates cGAS-STING Signaling

SummaryThe cGAS–STING signaling pathway has emerged as a key mediator of inflammation. However, the roles of chloride homeostasis on this pathway are unclear. Here, we uncovered a correlation between chloride homeostasis and cGAS-STING signaling.
Morse, Jared, Wang, Danna, Mei, Serena, Whitham, Danielle, Hladun, Colby, Darie, Costel C., Sintim, Herman O., Wang, Modi, Leung, KaHo   +8 more
openaire   +2 more sources

Hypothalamic Vitamin D Improves Glucose Homeostasis and Reduces Weight [PDF]

, 2016
Despite clear associations between vitamin D deficiency and obesity and/or type 2 diabetes, a causal relationship is not established. Vitamin D receptors (VDRs) are found within multiple tissues, including the brain.
Arble, Deanna M., Chambers, Adam P., Gardner, David, Gutierrez-Aguilar, Ruth, He, Yanlin, Moore, David D., Sandoval, Darleen A., Seeley, Randy J., Sisley, Stephanie R., Xu, Yong   +9 more
core   +4 more sources

Vitamin D and calcium metabolism in horses in New Zealand : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Veterinary Science at Institute of Veterinary, Animal and Biomedical Sciences (IVABS), Massey University, Manawatū, New Zealand [PDF]

, 2016
The physiology of vitamin D in horses has not been studied in great depth. Few studies on vitamin D metabolites (25OHD2, 25OHD3, and 1,25(OH)2D) and their relationship to other serum analytes exist. In addition, some studies suggest that equine vitamin D
Azarpeykan, Sara
core  

Renal neuroendocrine control of desiccation and cold tolerance by Drosophila suzukii [PDF]

, 2017
Background: Neuropeptides are central to the regulation of physiological, and behavioural processes in insects, directly impacting cold and desiccation survival.
Al-Anzi, Asplen, Atallah, Audsley, Cabrero, Cabrero, Cannell, Choi, Chown, Cini, Coast, Coast, Condon, Dalton, David, Davies, Denlinger, Dow, Dow, Enriquez, Gerken, Gibbs, Goodhue, Hadley, Halberg, Hoffmann, Hoffmann, Huey, Jakobs, Jakobs, Jensen, Kacar, Kahsai, Kang, Kean, Kelty, Li, Matsumura, Matzkin, McWilliam, Nässel, O'Donnell, Plantamp, Poyet, Rajpurohit, Ryan, Schiffer, Schooley, Shearer, Sinclair, Sinclair, Sinclair, Stephens, Sørensen, Taghert, Telonis-Scott, Terblanche, Terhzaz, Terhzaz, Terhzaz, Tochen, Toxopeus, Wallingford, Yeoh   +63 more
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Microbial metal resistance and metabolism across dynamic landscapes: high-throughput environmental microbiology. [PDF]

, 2017
Multidimensional gradients of inorganic compounds influence microbial activity in diverse pristine and anthropogenically perturbed environments. Here, we suggest that high-throughput cultivation and genetics can be systematically applied to generate ...
Carlson, Hans, Coates, John, Deutschbauer, Adam   +2 more
core   +2 more sources

Chloride Homeostasis and GABA Signaling in Temporal Lobe Epilepsy [PDF]

, 2012
Abstract Defects in GABAergic signaling have often been linked to the epilepsies. Suppressing fast inhibition mediated by gamma-aminobutyric acid A (GABAA) receptors initiates interictal-like activities in healthy brain tissue,1,2 and specific subgroups of interneurons seem to be especially sensitive to the neuronal death associated with
Miles, R., Blaesse, P., Huberfeld, G., Wittner, Lucia, Kaila, K.   +4 more
openaire   +1 more source

Serum chloride levels in critical illness—the hidden story

Intensive Care Medicine Experimental, 2018
Chloride is the principal anion of the extracellular fluid and vital for both serum electroneutrality and acid-base homeostasis. The aim of this review is to investigate the relevance of dyschloremia in the critically ill.
Carmen Andrea Pfortmueller, Dominik Uehlinger, Stephan von Haehling, Joerg Christian Schefold   +3 more
doaj   +1 more source

IRBIT a Master Regulator of Cell Physiology [PDF]

, 2017
(excerpt) Hormones and neurotransmitters regulate cell functions by binding to their receptors, which activate intracellular signaling and produce the physiological response [1].
Bouyer, Patrice G, Cook, Kelli, Petreska, Natasa   +2 more
core   +1 more source

Ouabain-induced cytoplasmic vesicles and their role in cell volume maintenance [PDF]

, 2015
Cellular swelling is controlled by an active mechanism of cell volume regulation driven by a Na+/K+-dependent ATPase and by aquaporins which translocate water along the osmotic gradient. Na+/K+-pump may be blocked by ouabain, a digitalic derivative, by
MORGANTE, Emanuela, Rossum, G. D. Van, Russo, A., RUSSO, Matteo Antonio, TAFANI, MARCO   +4 more
core   +1 more source

Impact of Age and Body Site on Adult Female Skin Surface pH [PDF]

, 2012
Background: pH is known as an important parameter in epidermal barrier function and homeostasis. Aim: The impact of age and body site on skin surface pH (pH(SS)) of women was evaluated in vivo.
Barbara Behm, Barland CO, Behne MJ, Behne MJ, Braun-Falco O, Choi EH, Dikstein S, Elias PM, Fluhr JW, Fluhr JW, Ghadially R, Ghadially R, Giusti F, Hachem JP, Hans Christian Korting, Hoeger PH, Kim EJ, Kocinkova AS, Korting HC, Korting HC, Kürner JM, Lambers H, Liebsch G, Mauro T, Michael Landthaler, Philipp Babilas, Posch HE, Robert Johannes Meier, Schmid-Wendtner MH, Schmuth M, Schreml S, Schreml S, Seyfarth F, Stephan Schreml, Takagi Y, Veronika Zeller, Wilhelm KP, Ye J, Yosipovitch G, Yosipovitch G, Zlotogorski A   +40 more
core   +2 more sources