Results 111 to 120 of about 71,553 (309)

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

Chlorogenic Acid Isolation from Coffee as Affected by the Homogeneity of Cherry Maturity

Coffee and Cocoa Research Journal, 2019
Chlorogenic acid is a polyphenol compound which has an antioxidant properties. The objectives of this research are to understand and compare the characteristics of caffeine, chlorogenic acid, and polyphenolic content in Robusta coffee treated differently.
Husniati Husniati, Devi Oktiani
doaj  

Phytochemicals in MASLD: A Focused Review of Gut Microbiome‐Linked Mechanisms

Phytotherapy Research, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as a major global health burden, yet effective pharmacological options remain limited. Recent advances highlight the gut microbiome as a key modulator of liver metabolism, inflammation, and fibrosis, making it a promising therapeutic target.
Jeong In Seo, Su Min Kim, Hye Hyun Yoo
wiley   +1 more source

The Effect of Combined Elicitation with Light and Temperature on the Chlorogenic Acid Content, Total Phenolic Content and Antioxidant Activity of Berula erecta in Tissue Culture

Plants
Chlorogenic acid is one of the most prominent bioactive phenolic acids with great pharmacological, cosmetic and nutritional value. The potential of Berula erecta in tissue culture was investigated for the production of chlorogenic acid and its ...
Jan Senekovič, Terezija Ciringer, Jana Ambrožič-Dolinšek, Maša Islamčević Razboršek   +3 more
doaj   +1 more source

Potential of Chlorogenic Acid from Coffea canephora to Improving Innate Immunity System Components among BALB / c Mice

, 2021
Christina Destri, Jusak Nugraha, Muhammad Amin, Djoko Agus Purwanto, C Biondo, G Entini, C Beninati, G Teti, H Takashi, C Pierre, T Richey, J Foster, A Williams, A Williams, A Stroh, Macy Wall, J, L M & Stuart, R Ezekowitz, E Uribe-Querol, C Rosales, S Rabadi, B Sanchez, M Varanat, Z Ma, S Catlett, J Melendez, C Bakshi, K Gilljam, K Holm, M Zahoor, F Centonze, H Farhan, H Blomhoff, R Poole, O Kennedy, P Roderick, J Fallowfield, P Hayes, J Parkes, K Krl, M Gantner, A Tatarak, E Hallmann, R Thimmulappa, H Lee, T Rangasamy, S Reddy, M Yamamoto, T Kensler, S Biswal, M Aritanoga, C Effendi, N Tajik, M Tajik, I Mack, P Enck, Ecb Milner, J Anolik, A Cappione, I Sanz   +60 more
openalex   +2 more sources

Antiprotozoal activity of flavonoids from Eupatorium arnottianum [PDF]

, 2017
Dichloromethane and ethanol extracts of Eupatorium arnottianum were evaluated for invitroleishmanicidal activity. The dichloromethane extract produced 80% and 85% of growthinhibition on both Leishmania mexicana and Leishmania amazonensis promastigotes ...
Cazorla, Silvia Ines, Clavin, Maria Liliana, Frank, Fernanda María, Malchiodi, Emilio Luis, Martino, Virginia Susana, Muschietti, Liliana Victoria, Sosa, Miguel Angel, Spina Zapata, Renata María   +7 more
core  

Knocking Out Two Polyphenol Oxidase Genes Significantly Improves Recombinant Protein Purification in Nicotiana benthamiana

Plant Biotechnology Journal, EarlyView.
ABSTRACT Efficient purification remains a key technical challenge affecting the recovery efficiency of recombinant proteins in plant‐based systems. Complex metabolites, particularly polyphenols, often cause recombinant protein aggregation during purification.
Hai‐Ping Diao, Hui‐Xin Meng, Xue‐Jiao Xu, Zeng‐Lin Zhang, Jian‐Feng Zhang, Yong‐Feng Guo, Inhwan Hwang, Shi‐Jian Song   +7 more
wiley   +1 more source

Development of a New Method of Storage and Maximum Separation of Chlorophils From Chlorophylcontaining Vegetables at Reception of Healthfull Nanoproducts [PDF]

, 2018
The aim of the work is the development of a new way of deep processing of chlorophyll-containing vegetables that gives a possibility not only to preserve chlorophylls a and b and other biologically active substances (BAS) of raw materials, but also to ...
Bessarab, O. (Olexandr), Mikhaylov, V. (Valeriy), Pavlyuk, R. (Raisa), Pogarska, V. (Viktoriya), Pogarskiy, A. (Aleksey), Radchenko, A. (Anna), Radchenko, L. (Ludmila), Telenkov, O. (Oleksandr)   +7 more
core   +2 more sources

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

Plant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan, Farkhandah Jan, Mukesh Rathore, Yogita Singh, Prexha Kapoor, Palak Chaturvedi, Arindam Ghatak, Palakurthi Ramesh, Upendra Kumar, Manoj Prasad, Sundeep Kumar, Sachin Rustgi, Wolfram Weckwerth, Sanjay Kalia, Rajeev Kumar Varshney, Reyazul Rouf Mir   +15 more
wiley   +1 more source

Protective Activity of Broccoli Sprout Juice in a Human Intestinal Cell Model of Gut Inflammation [PDF]

, 2016
Benefits to health from a high consumption of fruits and vegetables are well established and have been attributed to bioactive secondary metabolites present in edible plants.
Baima, Simona, Ferruzza, Simonetta, Giusti, Anna Maria, Maldini, Mariateresa, Mattivi, Fulvio, Moneta, Elisabetta, Morelli, Giorgio, Murgia, Chiara, Nardini, Mirella, Natella, Fausta, Ranaldi, Giulia, Rossi, Carlotta, Sambuy, Yula, Scaccini, Cristina, Trošt, Kajetan   +14 more
core   +3 more sources