Results 91 to 100 of about 44,002 (262)

Rate of living IPEC-J2 cells after chlorogenic acid treatment. [PDF]

open access: yes, 2016
Cell viability was measured by Neutral Red uptake method. Effect of chlorogenic acid on cell viability was studied in a dose-(CGA concentrations: 25 μM, 50 μM and 100 μM) and in a time-dependent manner (treatment time: 1 h, 4 h and 24 h).
Erzsébet Pászti-Gere (3353606)   +3 more
core   +1 more source

Chlorogenic acid inhibits intestinal lipid uptake and promotes adipose lipid catabolism via epithelium-derived exosomes in ob/ob mice

open access: yesFrontiers in Physiology
Chlorogenic acid has been widely reported to regulate lipid metabolism and alleviate obesity; however, its effects on intestinal lipid uptake and adipose tissue catabolism, as well as the underlying mechanisms, remain incompletely understood.
Yongwang Yan   +3 more
doaj   +1 more source

Harnessing Natural Compounds in Psoriasis: Targeting Cellular Pathways for Effective Therapy

open access: yesPhytotherapy Research, EarlyView.
Natural compounds act on key cellular pathways in psoriasis by suppressing keratinocyte hyperproliferation, modulating Th17/IL‐17‐mediated immune responses, and reducing oxidative stress. These multi‐target effects highlight their potential as safer adjunctive therapies alongside conventional treatments.
Hye Jin Lee   +9 more
wiley   +1 more source

Trapping by amylose of the aliphatic chain grafted onto chlorogenic acid: Importance of the graft position [PDF]

open access: yes, 2015
5-Caffeoylquinic acid (chlorogenic acid), is classified in acid-phenols family and as polyphenolic compounds it possesses antioxidant activity. The oxydative modification of chlorogenic acid in foods may lead to alteration of their qualities; to ...
Le-Bail, Patricia   +10 more
core   +1 more source

Quality by design approach for development and characterization of solid lipid nanoparticles of chlorogenic acid

open access: yesResults in Chemistry
Chlorogenic acid is a polyphenol that has potent antioxidant and antidepressant activity. Chlorogenic acid is a BCS class-III category compound (high solubility and low permeability). Due to low permeability and extensive first-pass metabolism (resulting
Tarapati Rana   +2 more
doaj   +1 more source

Ashwagandha: Is It Safe? Part 2: A Preclinical Evidence Review

open access: yesPhytotherapy Research, EarlyView.
ABSTRACT The preclinical evidence for the safety of ashwagandha (Withania somnifera (L.) Dunal, AS) is reviewed, and its preparations (extracts) and constituents, from the general toxicity in animal models to in vitro and cell culture studies, which may elucidate mechanisms of action and explain clinical case reports.
Elizabeth M. Williamson, Thomas Brendler
wiley   +1 more source

Protective effect of chlorogenic acid in an experimental model of Parkinson’s disease induced by 6-hydroxydopamine in rats

open access: yesMajallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Shahīd Ṣadūqī Yazd, 2019
Introdution: Parkinson's disease is the second most common neurodegenerative disease. Considering the antioxidant and neuroprotective properties of chlorogenic acid, the purpose of this study was to evaluate the neuroprotective effect of this substance ...
Saeedeh Dehnad   +2 more
doaj  

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

open access: yesPhytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi   +15 more
wiley   +1 more source

Biotransformation of chlorogenic acid by L. collinoides, as demonstrated with HPLC. [PDF]

open access: yes, 2016
Y-axis = absorbance at 254nm (mAU), X-axis = minutes. Top panel: HPLC of chlorogenic acid standard. Middle panel: HPLC of 4-vinylcatechol and 4-ethylcatechol standards. Bottom panel: HPLC of supernatant from chlorogenic acid + L.
Donald R. Senger (239111)   +3 more
core   +1 more source

RNA-seq analysis of chlorogenic acid intervention in duck embryo fibroblasts infected with duck plague virus

open access: yesVirology Journal
Introduction Chlorogenic acid, the primary active component in Chinese medicines like honeysuckle, exhibits anti-inflammatory and antiviral effects. It has been demonstrated that chlorogenic acid effectively prevents and treats Duck enteritis virus (DEV)
Yunyun Yang   +6 more
doaj   +1 more source

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