Results 101 to 110 of about 44,002 (262)

Feiwei Heji Enhances Antitumor Immunity by MLL4‐Dependent Regulation of Pyroptosis in Lung Cancer

Cancer Science, EarlyView.
Feiwei Heji suppresses lung tumor growth by downregulating MLL4 and activating caspase‐1/GSDMD‐associated pyroptosis. This pyroptosis‐related inflammatory response enhances CD8+ T‐cell‐mediated antitumor immunity, revealing an MLL4‐pyroptosis‐immune axis underlying the therapeutic activity of Feiwei Heji.
Nan Cheng, Ruoyu Jiang, Wei Li, Wenjie Huang, Qiao Peng, Tong Zhao, Chufeng Zhang   +6 more
wiley   +1 more source

Chlorogenic Acid and Synthetic Chlorogenic Acid Derivatives:  Novel Inhibitors of Hepatic Glucose-6-phosphate Translocase [PDF]

, 2016
The enzyme system glucose-6-phosphatase (EC 3.1.3.9) plays a major role in the homeostatic regulation of blood glucose. It is responsible for the formation of endogenous glucose originating from gluconeogenesis and glycogenolysis.
Peter Below (3019803), Peter W. Schindler (3019794), Andreas W. Herling (2241988), Robert Rippel (3019800), Erich Paulus (3019806), Horst Hemmerle (3019791), Hans-Joerg Burger (3019797), Gerrit Schubert (3019809)   +7 more
core   +1 more source

Powdered hibiscus anthocyanin‐nanofibril complexes as natural colourants: Stability and application in yoghurt and soft candy

Coloration Technology, EarlyView.
Abstract The instability of anthocyanins limits their application as natural food colorants. This study aimed to enhance the stability of anthocyanins extracted from Hibiscus sabdariffa through copigmentation with protein nanofibrils produced from pea, rice, gluten and whey isolates. Linear and curly nanofibril structures were prepared and incorporated
Vildan Eyiz, İsmail Tontul, Selman Türker   +2 more
wiley   +1 more source

Chlorogenic Acid Isolation from Coffee as Affected by the Homogeneity of Cherry Maturity

Coffee and Cocoa Research Journal, 2019
Chlorogenic acid is a polyphenol compound which has an antioxidant properties. The objectives of this research are to understand and compare the characteristics of caffeine, chlorogenic acid, and polyphenolic content in Robusta coffee treated differently.
Husniati Husniati, Devi Oktiani
doaj  

Exploration of Degradation Mechanism of Chlorogenic Acids in Stevia Based on UPLC-QTOF MS/MS

Zhipu Xuebao
Chlorogenic acids (caffeoylquinic acids, CQAs), as key bioactive components in numerous traditional herbal medicines, are highly acclaimed for their various biological activities and therapeutic benefits.
Juan-juan WU, Zi-xuan WANG, Yun-he LIAN, Li-juan HOU, Zhi-ping NIU, Wen-chang WANG, Di WU   +6 more
doaj   +1 more source

Unravelling polyphenol skin permeation: A comparative study using full‐thickness 3D in vitro and ex vivo human skin models

International Journal of Cosmetic Science, EarlyView.
This study demonstrates that full‐thickness 3D in vitro skin models reliably assess the permeation of cosmetic polyphenols, revealing compound‐specific transport profiles and bridging the gap between conventional cell models and ex vivo human skin, while offering an ethical and robust alternative for dermal absorption screening. Abstract The evaluation
Mariana Marques, Filipa Teixeira, Mónica Vieira, M. Helena Amaral, Paulo C. Costa, Stefano Dall'Acqua, Francisca Rodrigues   +6 more
wiley   +1 more source

Salinity Stress Is Beneficial to the Accumulation of Chlorogenic Acids in Honeysuckle (Lonicera japonica Thunb.) [PDF]

, 2016
Honeysuckle (Lonicera japonica Thunb.) is a traditional medicinal plant in China that is particularly rich in chlorogenic acids, which are phenolic compounds with various medicinal properties. This study aimed to examine the effects of salinity stress on
Cui, MX, Yan, K, Tang, XL, Yan, K (reprint author), Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Environm Proc & Ecol Remediat, Yantai, Peoples R China. Email:kyan@yic.ac.cn, Chen, XB, Zhao, SJ   +5 more
core   +1 more source

Effect of Chlorogenic Acid and Neochlorogenic Acid on Human Colon Cancer Cells [PDF]

, 2012
Prune consumption has been associated with a decreased risk of colon cancer, yet there has been confusion as to which chemical component(s) of the prune are responsible for its anticarcinogenic properties.
Thurow, Taylor
core   +4 more sources

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, EarlyView.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Histopathological investigation of wound healing activities of Lucilia sericata Larva and Achillea sintenisii extract combinations in diabetic rat wound model

Medical and Veterinary Entomology, EarlyView.
Lucilia sericata larvae secrete bioactive compounds that promote wound debridement and antimicrobial defence in chronic tissue injuries. Achillea sintenisii extract offers phytotherapeutic support, enhancing healing through anti‐inflammatory and regenerative properties. Diabetic Wistar rats were treated topically with Furacin®, larval secretions, plant
Nevra Polat, Salih Mollahaliloğlu, Murat Koç   +2 more
wiley   +1 more source