Results 171 to 180 of about 139,121 (234)

Liver-directed gene therapy results in amelioration of progressive familial intrahepatic cholestasis type 2 in mice. [PDF]

Hepatol Commun
Molina A, Trigueros-Motos L, Molina M, Martínez-García J, Palomo L, Pérez G, Odriozola L, Gázquez C, Tamarit B, Van Faassen M, Verkade HJ, Bouquet C, Combal JP, González-Aseguinolaza G, Smerdou C.   +14 more
europepmc   +1 more source

Fulminant <i>Brucella melitensis</i> Infection Presenting With Severe Cholestatic Hepatitis, Acute Kidney Injury, and Disseminated Intravascular Coagulation: A Case Report. [PDF]

Case Rep Infect Dis
Yıldız F, Manici E, Mert HTE, İnal V.
europepmc   +1 more source

Familial cholestasis: Progressive familial intrahepatic cholestasis, benign recurrent intrahepatic cholestasis and intrahepatic cholestasis of pregnancy

Bailliere's Best Practice and Research in Clinical Gastroenterology, 2010
Progressive familial intrahepatic cholestasis (PFIC) type 1, 2 and 3 are due to mutations in ATP8B1, ABCB11 and ABCB4, respectively. Each of these genes encodes a hepatocanalicular transporter, which is essential for the proper formation of bile. Mutations in ABCB4 can result in progressive cholestatic disease, while mutations in ATP8B1 and ABCB11 can ...
Saskia van Mil, Leo W J Klomp, Roderick H J Houwen   +2 more
exaly   +5 more sources

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Intrahepatic cholestasis of pregnancy

Česká gynekologie
Objective: The aim of this work is to summarize current scientific information focusing on the diagnosis, management, and treatment of intrahepatic cholestasis in pregnancy according to available literature. Methodology: Literature sources were searched using the Web of Science, Scopus, and PubMed/Medline databases.
E. Dajti, Valeria Tripodi, Ya-Yi Hu, M. Estiù, Shan Dan, G. Mazzella, F. Azzaroli   +6 more
semanticscholar   +9 more sources

Intrahepatic cholestasis of pregnancy [PDF]

BMJ, 2016
#### What you need to know A 30 year old, 35 week pregnant, nulliparous woman visits her general practitioner because of itching but no rash. Fundal height measurements and fetal movements are normal. The GP arranges an urgent antenatal clinic review, where liver function tests (LFTs), including bile acids, are reported as normal.
Sarah C, Hillman, Helen, Stokes-Lampard, Mark D, Kilby   +2 more
openaire   +3 more sources

Overview of Progressive Familial Intrahepatic Cholestasis.

Clinical Liver Disease, 2022
Bile acid transport is a complex physiologic process, of which disruption at any step can lead to progressive intrahepatic cholestasis (PFIC). The first described PFIC disorders were originally named as such before identification of a genetic cause ...
S. Hassan, P. Hertel
semanticscholar   +1 more source

Beyond stillbirth: association of intrahepatic cholestasis of pregnancy severity and adverse outcomes.

American Journal of Obstetrics and Gynecology, 2022
BACKGROUND Intrahepatic cholestasis of pregnancy is associated with adverse pregnancy outcomes, including sudden fetal cardiac arrhythmias, resulting in stillbirth.
Minhazur R. Sarker, A. Zamudio, C. DeBolt, L. Ferrara   +3 more
semanticscholar   +1 more source