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Intrahepatic Cholestasis of Pregnancy [PDF]

BMJ, 2016
#### What you need to know A 30 year old, 35 week pregnant, nulliparous woman visits her general practitioner because of itching but no rash. Fundal height measurements and fetal movements are normal. The GP arranges an urgent antenatal clinic review, where liver function tests (LFTs), including bile acids, are reported as normal.
Ovadia, Caroline, Williamson, Catherine
core   +3 more sources

Congenital thrombophilia associated with intrahepatic cholestasis of pregnancy. A case report [PDF]

Folia Medica, 2022
Intrahepatic cholestasis of pregnancy is pregnancy-specific liver disorder, characterized by pruritus as the main clinical symptom, and fasting liver function tests.
Corina Iliadi-Tulbure, Maria Cemortan, Cristina Bubulici, Mihaela Botnari-Gutu, Olga Cernetchi   +4 more
doaj   +3 more sources

Distribution of endotoxin in maternal and fetal body with intrahepatic cholestasis of pregnancy and its association with adverse fetal outcome

BMC Pregnancy and Childbirth, 2022
Background Intrahepatic cholestasis of pregnancy is a pregnancy-specific liver disease. In this study, we sought to explore the distribution of lipopolysaccharide in the maternal body, and its effect on the fetal body in the intrahepatic cholestasis of ...
Xiaomei Huang, Lei Lei, Fan Feng, Yong Shao   +3 more
doaj   +1 more source

Intrahepatic Cholestasis of Pregnancy [PDF]

Geburtshilfe und Frauenheilkunde, 2021
AbstractIntrahepatic cholestasis of pregnancy (ICP) is a rare but potentially serious complication of pregnancy, the main symptom of which is intense pruritus with elevated serum levels of bile acids. The elevated serum bile acid concentration is regarded as a predictor for poor perinatal outcome including intrauterine death. Ursodeoxycholic acid (UDCA)
Jurk, Stanisław M., Kremer, Andreas E., Schleussner, Ekkehard   +2 more
openaire   +2 more sources

A novel homozygous mutation in the USP53 gene as the cause of benign recurrent intrahepatic cholestasis in children: a case report

The Turkish Journal of Pediatrics, 2023
Background. Benign recurrent intrahepatic cholestasis (BRIC) is a rare cause of cholestasis with recurrent episodes of jaundice and pruritus without extrahepatic bile duct obstruction.
Burcu Berberoğlu Ateş, Ahmet Cevdet Ceylan, Gülin Hızal, Fatih Duran, Hayriye Tatlı Doğan, Şamil Hızlı   +5 more
doaj   +1 more source

Intrahepatic cholestasis of pregnancy [PDF]

World Journal of Gastroenterology, 2009
Intrahepatic cholestasis of pregnancy is the most common pregnancy-specific liver disease that typically presents in the third trimester. The clinical features are maternal pruritus in the absence of a rash and deranged liver function tests, including raised serum bile acids. Intrahepatic cholestasis of pregnancy is associated with an increased risk of
Williamson, Catherine, Geenes, Victoria
openaire   +4 more sources

IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases and is farnesoid X receptor responsive in NASH

Hepatology, EarlyView., 2022
IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu, Ya Wang, Mina Khoshdeli, Matt Peach, Jen‐Chieh Chuang, Julie Lin, Wen‐Wei Tsai, Sangeetha Mahadevan, Wesley Minto, Lauri Diehl, Ruchi Gupta, Michael Trauner, Keyur Patel, Mazen Noureddin, Kris V. Kowdley, Aliya Gulamhusein, Christopher L. Bowlus, Ryan S. Huss, Robert P. Myers, Chuhan Chung, Andrew N. Billin   +20 more
wiley   +1 more source

Effects of cytomegalovirus infection on the differential diagnosis between biliary atresia and intrahepatic cholestasis in a Chinese large cohort study

Annals of Hepatology, 2021
Introduction and objectives: Differentiating biliary atresia from other causes of neonatal cholestasis is challenging, particularly when cytomegalovirus (CMV) and biliary atresia occur simultaneously.
Dongying Zhao, Xiaohui Gong, Yahui Li, Xiaoang Sun, Yan Chen, Zhaohui Deng, Yongjun Zhang   +6 more
doaj   +1 more source

INTRAHEPATIC CHOLESTASIS IN PREGNANCY [PDF]

Praxis medica, 2013
<p>Abnormal liver function tests occur in 3-5% of pregnancies, with many potential causes, including coincidental liver disease (most commonly viral hepatitis or gallstones) and underlying chronic liver disease. Pruritus in pregnancy is common, affecting 23% of pregnancies, of which a small proportion will have obstetric cholestasis ...
Savić Ž., Stojilković T., Rankov O., Vračarić V., Jocić T., Damjanov D.   +5 more
openaire   +2 more sources

Mitochondrial stress in advanced fibrosis and cirrhosis associated with chronic hepatitis B, chronic hepatitis C, or nonalcoholic steatohepatitis

Hepatology, EarlyView., 2022
Adaptive mitochondrial mechanisms allow mitochondrial resilience and prevent the worsening of fibrosis, while deregulation of these mechanisms promotes the progression from no/minimal‐mild (F0‐F2) fibrosis to advanced fibrosis and cirrhosis (F3‐F4). Abstract Background and Aims Hepatitis B virus (HBV) infection causes oxidative stress (OS) and alters ...
Dimitri Loureiro, Issam Tout, Stéphanie Narguet, Cheikh Mohamed Bed, Morgane Roinard, Ahmad Sleiman, Nathalie Boyer, Nathalie Pons‐Kerjean, Corinne Castelnau, Nathalie Giuly, Dorothy Tonui, Vassili Soumelis, Jamel El Benna, Patrick Soussan, Richard Moreau, Valérie Paradis, Abdellah Mansouri, Tarik Asselah   +17 more
wiley   +1 more source