Results 21 to 30 of about 260,746 (260)

Effects of dietary cholesterol and fatty acids on plasma cholesterol level and hepatic lipoprotein metabolism.

Journal of Lipid Research, 1990
The effects of dietary cholesterol and fatty acids on the plasma cholesterol level and rates of very low density lipoprotein (VLDL) cholesterol secretion and low density lipoprotein (LDL) transport through LDL receptors in the liver of the hamster were ...
H Ohtani, K Hayashi, Y Hirata, S Dojo, K Nakashima, E Nishio, H Kurushima, M Saeki, G Kajiyama   +8 more
doaj   +1 more source

Existing and emerging therapies for the treatment of familial hypercholesterolemia

Journal of Lipid Research, 2021
Familial hypercholesterolemia (FH), an autosomal dominant disorder of LDL metabolism that is characterized by elevated LDL-cholesterol, is commonly encountered in patients with atherosclerotic coronary heart disease.
Robert S. Rosenson
doaj   +1 more source

Association between low-density lipoprotein cholesterol and sudden cardiac arrest in people with diabetes mellitus

Cardiovascular Diabetology, 2023
Background Dyslipidemia measured as low-density lipoprotein (LDL)-cholesterol is an established risk factor of cardiovascular disease, which is more pronounced in diabetes population.
Yun Gi Kim, Joo Hee Jeong, Kyung-Do Han, Seung-Young Roh, Kyongjin Min, Hyoung Seok Lee, Yun Young Choi, Jaemin Shim, Jong-Il Choi, Young-Hoon Kim   +9 more
doaj   +1 more source

Cholesterol delivered to macrophages by oxidized low density lipoprotein is sequestered in lysosomes and fails to efflux normally

Journal of Lipid Research, 2000
Oxidized low density lipoprotein (LDL) has been found to exhibit numerous potentially atherogenic properties, including transformation of macrophages to foam cells.
Baljinder S. Dhaliwal, Urs P. Steinbrecher   +1 more
doaj   +1 more source

Differences in the metabolism of oxidatively modified low density lipoprotein and acetylated low density lipoprotein by human endothelial cells: inhibition of cholesterol esterification by oxidatively modified low density lipoprotein.

Journal of Lipid Research, 1989
The rate of degradation of oxidatively modified low density lipoprotein (Ox-LDL) by human endothelial cells was similar to that of unmodified low density lipoprotein (LDL), and was approximately 2-fold greater than the rate of degradation of acetylated ...
I Jialal, A Chait
doaj   +1 more source

LDL particle size and LDL and HDL cholesterol changes with dietary fat and cholesterol in healthy subjects

Journal of Lipid Research, 1998
We have conducted a dietary trial in 54 men and 51 women with a wide range of fasting cholesterol values to examine the use of low density lipoprotein (LDL) particle size to predict the lipoprotein response to dietary fat and cholesterol.
Peter M. Clifton, Manny Noakes, Paul J. Nestel   +2 more
doaj   +1 more source

Cholesterol deposition in macrophages: foam cell formation mediated by cholesterol-enriched oxidized low density lipoprotein.

Journal of Lipid Research, 1997
Oxidized low density lipoprotein (LDL) is thought to mediate the transformation of macrophages to cholesterol-rich foam cells. Yet convincing evidence for this process is lacking in vitro.
P Greenspan, H Yu, F Mao, R L Gutman
doaj   +1 more source

Decrease of LDL Cholesterol Through The Increase of HDL Cholesterol by Administering Garcinia mangostana L. Peel Extract in White Mice

Folia Medica Indonesiana, 2021
Highlight: • Ethanol extract of Garcinia mangostana L. peel reduce malondialdehyde. • Garcinia mangostana L. peel extract can increase non-radical products which impact in decreasing LDL cholesterol and increasing HDL cholesterol.
Hasyim As'ari
doaj   +1 more source

Lipoprotein metabolism in familial hypercholesterolemia: Serial assessment using a one-step ultracentrifugation method

Practical Laboratory Medicine, 2015
Objectives: It is well known that familial hypercholesterolemia (FH) is a common inherited disorder that can markedly elevate the level of plasma LDL cholesterol.
Hayato Tada, Masa-aki Kawashiri, Atsushi Nohara, Akihiro Inazu, Hiroshi Mabuchi, Masakazu Yamagishi, Kenshi Hayashi   +6 more
doaj   +1 more source

Influence of an atherogenic diet on the structure of swine low density lipoproteins

Journal of Lipid Research, 1980
Five groups of three swine each were fed a basal diet supplemented with 15% tallow and either 0.0, 1.0, 1.5, 2.0%, or 2.5% cholesterol. The animals were studied over a period of 9 weeks to observe changes in plasma lipids and low density lipoproteins ...
H J Pownall, R L Jackson, R I Roth, A M Gotto, J R Patsch, F A Kummerow   +5 more
doaj   +1 more source