Results 31 to 40 of about 297,626 (305)

Electronegative LDL is linked to high-fat, high-cholesterol diet-induced nonalcoholic steatohepatitis in hamsters [PDF]

open access: yes, 2017
The pathogenesis of nonalcoholic steatohepatitis (NASH), like that of atherosclerosis, involves lipid accumulation, inflammation and fibrosis. Recent studies suggest that oxidized LDL (oxLDL) may be a risk factor for NASH, but oxLDL levels were not ...
Lai, Yu-Sheng;Yang, Tzu-Ching;Chang, Po-Yuan;Chang, Shwu-Fen;Ho, Shu-Li;Chen, Hui-Ling;Lu, Shao-Chun   +1 more
core   +1 more source

Lipoprotein metabolism in familial hypercholesterolemia: Serial assessment using a one-step ultracentrifugation method

open access: yesPractical Laboratory Medicine, 2015
Objectives: It is well known that familial hypercholesterolemia (FH) is a common inherited disorder that can markedly elevate the level of plasma LDL cholesterol.
Hayato Tada   +6 more
doaj   +1 more source

Influence of an atherogenic diet on the structure of swine low density lipoproteins

open access: yesJournal of Lipid Research, 1980
Five groups of three swine each were fed a basal diet supplemented with 15% tallow and either 0.0, 1.0, 1.5, 2.0%, or 2.5% cholesterol. The animals were studied over a period of 9 weeks to observe changes in plasma lipids and low density lipoproteins ...
H J Pownall   +5 more
doaj   +1 more source

Interaction of aging and dietary fat in the regulation of low density lipoprotein transport in the hamster.

open access: yesJournal of Lipid Research, 1989
These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj   +1 more source

Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]

open access: yes, 1992
The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Jüngst, Dieter   +2 more
core   +1 more source

Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis

open access: yesJournal of Lipid Research, 2012
High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni   +9 more
doaj   +1 more source

Ox-LDL-mediated repletion of ATP6V0d2-KD cholesterol levels restores PV volumes and impacts parasite multiplication. [PDF]

open access: yes, 2019
A. Intracellular cholesterol levels displayed by nonsilenced or ATP6V0d2-KD macrophages treated or not with 50 μg/ml of ox-LDL for 48 hours, showing that ox-LDL replenishes the ~40% lower cholesterol amount of ATP6V0d2-KD to levels comparable to ...
Luiza Campos Reis (6843587)   +11 more
core   +1 more source

Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels

open access: yesJournal of Lipid Research, 2010
Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt   +3 more
doaj   +1 more source

Biochemical and cytotoxic characteristics of an in vivo circulating oxidized low density lipoprotein (LDL-).

open access: yesJournal of Lipid Research, 1994
Using ion exchange high pressure liquid chromatography, total plasma low density lipoprotein (LDL) from 30 hypercholesterolemic and 10 normocholesterolemic cynomolgus monkeys was subfractionated into unmodified LDL (n-LDL) and more negatively charged LDL
H.N. Hodis   +7 more
doaj   +1 more source

Subcellular localization and quantification of cholesterol in cultured human fibroblasts exposed to human low density lipoprotein

open access: yesJournal of Lipid Research, 1982
Subcellular localization of nonesterified cholesterol has been determined in normal human fibroblasts from cultures incubated with human low density lipoprotein (LDL).
H S Kruth   +4 more
doaj   +1 more source

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