Results 31 to 40 of about 297,274 (306)
Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels
Journal of Lipid Research, 2010 Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt +3 more
doaj +1 more source
Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]
, 1992 The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Jüngst, Dieter +2 more
core +1 more source
Journal of Lipid Research, 1989 These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj +1 more source
, 2023 Introduction: Atherosclerosis is the main cause of many cardiovascular diseases and contributes to morbidity and mortality worldwide. The formation of macrophage-derived foam cells plays a critical role in the early stage of atherosclerosis pathogenesis.
Xuewen Wu (11766797) +12 more
core +1 more source
Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis
Journal of Lipid Research, 2012 High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni +9 more
doaj +1 more source
Journal of Lipid Research, 1994 Using ion exchange high pressure liquid chromatography, total plasma low density lipoprotein (LDL) from 30 hypercholesterolemic and 10 normocholesterolemic cynomolgus monkeys was subfractionated into unmodified LDL (n-LDL) and more negatively charged LDL
H.N. Hodis +7 more
doaj +1 more source
Journal of Lipid Research, 1982 Subcellular localization of nonesterified cholesterol has been determined in normal human fibroblasts from cultures incubated with human low density lipoprotein (LDL).
H S Kruth +4 more
doaj +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic limb‐threatening ischemia (CLTI) is a severe form of lower‐extremity artery disease characterized by distal lesions and microcirculatory impairment, limiting revascularization efficacy. Rheocarna is a direct hemoperfusion low‐density lipoprotein (LDL) adsorption device with potential rheological and anti‐inflammatory ...
Kunihiro Ishioka +12 more
wiley +1 more source
Journal of Lipid Research, 1996 Effectiveness of a simultaneous inhibition of cholesterol absorption and synthesis, caused by sitostanol ester margarine and pravastatin, was studied to control mild hypercholesterolemia in men with non-insulin-dependent diabetes mellitus (NIDDM) (n = 8).
H Gylling, T A Miettinen
doaj +1 more source
Cardiovascular outcomes and LDL-cholesterol levels in EMPA-REG OUTCOME
Diabetes & Vascular Disease Research, 2020 Objective: It is well established that higher low-density lipoprotein (LDL)-cholesterol levels are associated with increased cardiovascular risk. We analyzed whether effects of empagliflozin on cardiovascular outcomes varied by different LDL-cholesterol ...
Gisle Langslet +6 more
doaj +1 more source