Results 31 to 40 of about 1,208,067 (300)

Time Course of LDL Cholesterol Exposure and Cardiovascular Disease Event Risk.

Journal of the American College of Cardiology, 2020
BACKGROUND Incident cardiovascular disease (CVD) increases with increasing low-density lipoprotein cholesterol (LDL-C) concentration and exposure duration. Area under the LDL-C versus age curve is a possible risk parameter.
M. Domanski, Xin Tian, Colin O. Wu, J. Reis, A. Dey, Yuan Gu, Lihui Zhao, S. Bae, Kiang Liu, Ahmed A. Hasan, D. Zimrin, M. Farkouh, Charles C. Hong, D. Lloyd-Jones, V. Fuster   +14 more
semanticscholar   +1 more source

Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects [PDF]

, 2010
Background -Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower high-density lipoprotein (HDL) cholesterol, raise low-density lipoprotein (LDL ...
Wanders Anne J., Siebelink, E., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Brouwer, I.A., Els Siebelink, Anne J. W, Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Siebelink Els, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +16 more
core   +4 more sources

Cholesterol deposition in macrophages: foam cell formation mediated by cholesterol-enriched oxidized low density lipoprotein.

Journal of Lipid Research, 1997
Oxidized low density lipoprotein (LDL) is thought to mediate the transformation of macrophages to cholesterol-rich foam cells. Yet convincing evidence for this process is lacking in vitro.
P Greenspan, H Yu, F Mao, R L Gutman
doaj   +1 more source

Remnant Cholesterol, Not LDL Cholesterol, Is Associated With Incident Cardiovascular Disease.

Journal of the American College of Cardiology, 2020
BACKGROUND Genetic, observational, and clinical intervention studies indicate that circulating levels of triglycerides and cholesterol transported in triglyceride-rich lipoproteins (remnant cholesterol) can predict cardiovascular events.
O. Castañer, X. Pintó, I. Subirana, A. Amor, E. Ros, Á. Hernáez, M. Martínez-González, D. Corella, J. Salas-Salvadó, R. Estruch, J. Lapetra, E. Gómez-Gracia, Á. Alonso-Gómez, M. Fiol, L. Serra-Majem, E. Corbella, D. Benaiges, J. Sorlí, M. Ruíz-Canela, N. Babio, L. T. Sierra, E. Ortega, M. Fitó   +22 more
semanticscholar   +1 more source

Lipoprotein metabolism in familial hypercholesterolemia: Serial assessment using a one-step ultracentrifugation method

Practical Laboratory Medicine, 2015
Objectives: It is well known that familial hypercholesterolemia (FH) is a common inherited disorder that can markedly elevate the level of plasma LDL cholesterol.
Hayato Tada, Masa-aki Kawashiri, Atsushi Nohara, Akihiro Inazu, Hiroshi Mabuchi, Masakazu Yamagishi, Kenshi Hayashi   +6 more
doaj   +1 more source

Influence of an atherogenic diet on the structure of swine low density lipoproteins

Journal of Lipid Research, 1980
Five groups of three swine each were fed a basal diet supplemented with 15% tallow and either 0.0, 1.0, 1.5, 2.0%, or 2.5% cholesterol. The animals were studied over a period of 9 weeks to observe changes in plasma lipids and low density lipoproteins ...
H J Pownall, R L Jackson, R I Roth, A M Gotto, J R Patsch, F A Kummerow   +5 more
doaj   +1 more source

Interaction of aging and dietary fat in the regulation of low density lipoprotein transport in the hamster.

Journal of Lipid Research, 1989
These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
doaj   +1 more source

Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis

Journal of Lipid Research, 2012
High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni, F. Zimetti, M. Puntoni, F. Bigazzi, F. Sbrana, F. Minichilli, F. Bernini, N. Ronda, E. Favari, T. Sampietro   +9 more
doaj   +1 more source

Remnant cholesterol, LDL cholesterol, and apoB absolute mass changes explain results of the PROMINENT trial.

Atherosclerosis
BACKGROUND AND AIMS The PROMINENT trial, a cardiovascular outcome trial of the triglyceride- and remnant cholesterol-lowering agent pemafibrate, has shown neutral results despite reduction in plasma triglycerides and remnant cholesterol.
Takahito Doi, A. Langsted, B. Nordestgaard   +2 more
semanticscholar   +1 more source

Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels

Journal of Lipid Research, 2010
Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt, William E. Alborn, Guoqing Cao, Robert J. Konrad   +3 more
doaj   +1 more source