Results 31 to 40 of about 260,746 (260)
Journal of Lipid Research, 1989 These studies were undertaken to examine the effect of aging on low density lipoprotein (LDL) metabolism in the male hamster. When the hamsters were maintained on a low-cholesterol, low-triglyceride diet, rates of LDL transport in the various tissues of ...
D K Spady, J M Dietschy
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Cellular cholesterol efflux and cholesterol loading capacity of serum: effects of LDL-apheresis
Journal of Lipid Research, 2012 High LDL-cholesterol (LDL-C) characterizes familial hypercholesterolemia (FH) and familial combined hyperlipidemia (FCH). LDL-apheresis, used in these patients to reduce LDL-C levels, has been shown to also affect HDL levels and composition.
M.P. Adorni +9 more
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Fenofibrate treatment increases human serum proprotein convertase subtilisin kexin type 9 levels
Journal of Lipid Research, 2010 Over the past several years, proprotein convertase subtilisin kexin type 9 (PCSK9) has gained significant attention as a key regulator of serum LDL-cholesterol (LDL-C) levels.
Jason S. Troutt +3 more
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Journal of Lipid Research, 1994 Using ion exchange high pressure liquid chromatography, total plasma low density lipoprotein (LDL) from 30 hypercholesterolemic and 10 normocholesterolemic cynomolgus monkeys was subfractionated into unmodified LDL (n-LDL) and more negatively charged LDL
H.N. Hodis +7 more
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Journal of Lipid Research, 1982 Subcellular localization of nonesterified cholesterol has been determined in normal human fibroblasts from cultures incubated with human low density lipoprotein (LDL).
H S Kruth +4 more
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Cardiovascular outcomes and LDL-cholesterol levels in EMPA-REG OUTCOME
Diabetes & Vascular Disease Research, 2020 Objective: It is well established that higher low-density lipoprotein (LDL)-cholesterol levels are associated with increased cardiovascular risk. We analyzed whether effects of empagliflozin on cardiovascular outcomes varied by different LDL-cholesterol ...
Gisle Langslet +6 more
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Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng +3 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
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Quantitation of the in vitro free cholesterol exchange of human red cells and lipoproteins
Journal of Lipid Research, 1970 The exchange of free cholesterol in vitro between human red blood cells and low density lipoproteins (LDL) was quantified. The flux of sterol between LDL and red cells was relatively constant over a wide range of concentrations of free cholesterol in ...
STEVEN H. QUARFORDT, HELEN L. HILDERMAN
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Standardization of Apolipoprotein B, LDL‐Cholesterol, and Non‐HDL‐Cholesterol
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023 Concern continues about whether the measurement of apolipoprotein B (apoB) is adequately standardized, and therefore, whether apoB should be applied widely in clinical care. This concern is misplaced.
John H. Contois +3 more
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