Results 171 to 180 of about 45,265 (208)

Clinical Application of Steroid Profiles and Their Interpretation in Adrenal Disorders. [PDF]

Diagnostics (Basel)
Ramasamy I.
europepmc   +1 more source

Heterozygous <i>CYP27B1</i> c.262delG pathogenic variant and its impact on vitamin D metabolites and phosphocalcic profile in humans. [PDF]

Front Physiol
Girard L, Fortin CA, Plourde R, Desgagné V, Guérin R, Albert C, Desmeules M, Perron P, Bouchard L.   +8 more
europepmc   +1 more source

Lipid metabolism dysregulation in solar lentigo: a multi-system-level analysis reveals membrane instability and energy homeostasis disruption. [PDF]

Front Cell Dev Biol
Kim S, Lee W, Kim J, Lee Y, Lee K, Kim MS, Kwon SH.   +6 more
europepmc   +1 more source

Cerebrotendinous Xanthomatosis: A Reversible Rarity if Caught on Time. [PDF]

Indian Dermatol Online J
Suresh P, Dev PP, Khunger N, Sharma S.
europepmc   +1 more source

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The role of cholesterol 25-hydroxylase in viral infections: Mechanisms and implications

Pathology - Research and Practice, 2023
Viral infections pose significant threats to human health, causing various diseases with varying severity. The intricate interactions between viruses and host cells determine the outcome of infection, including viral replication, immune responses, and disease progression.
Parastoo Yousefi, Ali Gholami, Mohsen Mehrjo, Mohammad Hossein Razizadeh, Mandana Akhavan, Sajad Karampoor, Alireza Tabibzadeh   +6 more
openaire   +2 more sources

Cholesterol 25-hydroxylase suppresses rabies virus infection by inhibiting viral entry

Archives of Virology, 2019
Cholesterol-25-hydroxylase (CH25H) is a reticulum-associated membrane protein that catalyzes the oxidation of cholesterol to 25-hydroxycholesterol (25HC). Recent studies have revealed that CH25H is an interferon-stimulated gene (ISG) that suppresses infection by several viruses.
Yueming Yuan, Zongmei Wang, Bin Tian, Ming Zhou, Zhen F. Fu, Ling Zhao   +5 more
openaire   +2 more sources

Cholesterol 25-hydroxylase inhibits Senecavirus A replication by enzyme activity-dependent and independent mechanisms

Veterinary Microbiology, 2021
Cholesterol 25-hydroxylase (CH25 H), as a host restriction factor, has been reported to take a broad-spectrum antiviral effect. However, the role of CH25H in Senecavirus A (SVA) infection remains unknown. In this study, we first demonstrate that overexpression of CH25H inhibits SVA replication.
Huixin, Zhu, Junfang, Yan, Xing, Liu, Liang, Li, Wenwen, Liu, Xianwei, Wang, Ping, Jiang, Juan, Bai   +7 more
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CYP109E1 from Bacillus megaterium Acts as a 24‐ and 25‐Hydroxylase for Cholesterol

ChemBioChem, 2019
AbstractIn this study, the ability of CYP109E1 from Bacillus megaterium DSM319 to metabolize cholesterol was investigated. This steroid was identified as a new substrate to be converted by CYP109E1 with adrenodoxin and adrenodoxin reductase as redox partners in vitro.
Natalia Putkaradze, Martin Litzenburger, Michael Christopher Hutter, Rita Bernhardt   +3 more
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Cholesterol 25-hydroxylase inhibits encephalomyocarditis virus replication through enzyme activity-dependent and independent mechanisms

Veterinary Microbiology, 2020
Cholesterol-25-hydroxylase (CH25 H) is a reticulum-associated membrane protein induced by an important interferon-stimulating gene (ISG) and can significantly inhibit some virus replication. But the effect of CH25H on encephalomyocarditis virus (EMCV) is still not clear. In this study, we found that EMCV infection increases significantly the endogenous
Shihai, Li, Liang, Li, Huixin, Zhu, Mengyu, Shi, Hui, Fan, YanNi, Gao, XianWei, Wang, Ping, Jiang, Juan, Bai   +8 more
openaire   +2 more sources