Results 161 to 170 of about 5,987 (179)

Engineering NK and T cells with metabolite-sensing receptors to target solid tumors. [PDF]

Nat Immunol
Kim YM, Tsai MK, Sun C, Laveroni O, Akana RV, Frombach K, Jerby L.   +6 more
europepmc   +1 more source

24S-Hydroxycholesterol: A potential brain-derived biomarker of Huntington’s Disease

Asgari MA, Langbehn DR, Skibinski DOF, Lee R, Griffiths WJ, Wang Y.   +5 more
europepmc   +1 more source

Cafestol, the Cholesterol-Raising Factor in Boiled Coffee, Suppresses Bile Acid Synthesis by Downregulation of Cholesterol 7α-Hydroxylase and Sterol 27-Hydroxylase in Rat Hepatocytes

Arteriosclerosis, Thrombosis, and Vascular Biology, 1997
Consumption of boiled coffee raises serum cholesterol levels in humans. The diterpenes cafestol and kahweol in boiled coffee have been found to be responsible for the increase.
Sabine M Post, Hans M G Princen
exaly   +2 more sources

Synthesis and pharmacokinetic study of a 11C-labeled cholesterol 24-hydroxylase inhibitor using ‘in-loop’ [11C]CO2 fixation method

Bioorganic and Medicinal Chemistry Letters, 2020
Cholesterol 24-hydroxylase is a monooxygenase encoded by CYP46A1, which is specifically expressed in the brain where it controls cholesterol elimination by producing 24S-hydroxylcholesterol (24-HC) as the major metabolite.
Zhen Chen, Jiahui Chen, Natalia Mast
exaly   +2 more sources

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Anticonvulsive properties of soticlestat, a novel cholesterol 24‐hydroxylase inhibitor

Epilepsia, 2022
Toshiya Nishi, Cameron S Metcalf, Shinji Fujimoto   +2 more
exaly  

An improved method for assay of cholesterol 7α-hydroxylase activity

Analytical Biochemistry, 1986
Tadashi Ogishima, Kyuichiro Okuda
exaly  

Assay of cholesterol 7α-hydroxylase activity in rat hepatocytes in primary monolayer culture

Analytical Biochemistry, 1988
Hans M G Princen, Jaap Kwekkeboom, H J Kempen   +2 more
exaly  

Structure of the gene encoding human liver cholesterol 7α-hydroxylase

Biochimica Et Biophysica Acta Gene Regulatory Mechanisms, 1993
Mitsuhide Noshiro, Kyuichiro Okuda
exaly  

Thyroid hormone rapidly increases cholesterol 7α-hydroxylase mRNA levels in hypophysectomized rats

Lipids and Lipid Metabolism, 1994
Gene C Ness, G C Ness
exaly  

Up to date on cholesterol 7 alpha-hydroxylase (CYP7A1) in bile acid synthesis

Liver Research, 2020
John Y L Chiang, Jessica M Ferrell
exaly