Results 71 to 80 of about 6,635 (224)

Molecular Mechanism of Mulberrin Regulating Lipid Metabolism Homeostasis Based on the Gut–Liver Axis Fiaf/AMPK Signaling Pathway

Food Frontiers, Volume 7, Issue 2, March 2026.
The molecular mechanism for mulberrin regulating lipid metabolism homeostasis. ABSTRACT Lipid metabolism disorders and the induced metabolic diseases have risen to become one of the primary public health issues. Our preliminary experimental results confirmed that mulberry leaf flavonoid extract exhibited efficacy in lipid metabolism regulation; the ...
Qian Li, Daorui Pang, Erna Li, Dongxu Xing, Fan Liu, Li Wang, Yuxiao Zou   +6 more
wiley   +1 more source

Schisantherin A: Remodeling Gut Microbiota to Activate the Gut–Immune–Neural–Adipose Axis for Thermogenesis

iNew Medicine, Volume 2, Issue 1, March 2026.
ABSTRACT The global obesity epidemic necessitates safe and effective strategies to enhance energy expenditure. Schisantherin A (Sin A), a lignan derived from Schisandra chinensis, has demonstrated metabolic benefits, yet its systemic mechanism remains unclear.
Ling Yin
wiley   +1 more source

The acidic pathway of bile acid synthesis: Not just an alternative pathway

Liver Research, 2019
Over the last two decades, the prevalence of obesity, and metabolic syndromes (MS) such as non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM), have dramatically increased.
William M. Pandak, Genta Kakiyama
doaj   +1 more source

Lipid peroxidation biomarkers for evaluating oxidative stress in equine neuroaxonal dystrophy. [PDF]

, 2018
BackgroundEquine neuroaxonal dystrophy/equine degenerative myeloencephalopathy (eNAD/EDM) is a neurodegenerative disorder affecting genetically predisposed foals maintained on an α-tocopherol (α-TOH) deficient diet.
Bordbari, Matthew H, Burns, Erin N, Estell, Krista E, Finno, Carrie J, Katzman, Scott, Miller, Andrew D, Puschner, Birgit, Tran, Cecilia K, Winfield, Laramie, Xu, Libin   +9 more
core  

Nutrient sensing, signal transduction and immune responses [PDF]

, 2016
Most cells in the body have a constant supply of nutrients, which are required to sustain cellular metabolism and functions. In contrast, cells of the immune system can encounter conditions with a limited nutrient supply during the course of an immune ...
Alvarez-Curto, Alvarez-Curto, Ananieva, Ananieva, Andersen, Arpaia, Atarashi, Bah, Balmer, Bar-Peled, Bauman, Benhamed, Bensinger, Bertolotti, Bharadwaj, Blagih, Bond, Briscoe, Brown, Brown, Carr, Chang, Chang, Chang, Chantranupong, Chen, Chou, Cobbold, Cui, Cummins, David Finlay, Delgoffe, Delgoffe, Diczfalusy, Donnelly, Donohoe, Fallarino, Feng, Fossati, Furusawa, Garcia-Navas, Glozak, Gold, Golks, Gonzalez, Grallert, Grebe, Hannedouche, Harig, Hart, Hart, Hayashi, Heine, Hirayama, Ho, Hockel, Hong, Horton, Hou, Hu, Huang, Ichimura, Im, Jabara, Jessica Walls, Kanai, Keil, Kidani, Kim, Kneass, Kneass, Le Poul, Linda Sinclair, Liu, Liu, Liu, Maciejewski-Lenoir, Macintyre, MacIver, Maianski, Mangalam, Maslowski, Mayer, Mukhopadhyay, Munger, Munn, Murakami, Nakaya, Nath, Nicklin, Noman, O'Neill, Oh, Orsini, Pallett, Piccoli, Pollizzi, Powell, Preston, Radhakrishnan, Ramakrishnan, Ravindran, Ravindran, Rawson, Rebsamen, Ripoli, Rodriguez, Rodriguez-Espinosa, Rolf, Rose, Ryu, Santori, Schaub, Scheppach, Sheedy, Sinclair, Singh, Smith, Soroosh, Spann, Steffensen, Su, Suzuki, Swamy, Talukdar, Tamune, Tang, Tarhda, Taylor, Thai, Thangaraju, Tremaroli, Urasaki, van Baren, Verbist, Vinolo, Vitko, Wang, Wang, Wang, Wang, Wang, Weichhart, Wolfson, Xing, Xu, Yan, Yang, Yang, York, York, Yu, Zeng, Zhong   +153 more
core   +2 more sources

Safety and Effectiveness of Pharmacy Compounded Chenodeoxycholic Acid Capsules for Patients With Cerebrotendinous Xanthomatosis

Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.
ABSTRACT Chenodeoxycholic acid (CDCA) is an essential drug for patients with rare metabolic disease cerebrotendinous xanthomatosis (CTX). To ensure continuation of treatment, the Amsterdam UMC hospital pharmacy developed pharmacy compounded CDCA capsules when the authorized CDCA capsules were no longer available for Dutch patients.
Natalja Bouwhuis, Soumia Majait, Yasmin Polak, Aylene de Jong, Bart A. W. Jacobs, Frédéric M. Vaz, Willemijn G. Leen, E. Marleen Kemper, Eleonora L. Swart, Carla E. M. Hollak   +9 more
wiley   +1 more source

Marked reduction in bile acid synthesis in cholesterol 7α-hydroxylase-deficient mice does not lead to diminished tissue cholesterol turnover or to hypercholesterolemia

Journal of Lipid Research, 1998
These studies used mice that were deficient in cholesterol 7α-hydroxylase to determine the effects of reduced bile acid synthesis on cholesterol homeostasis.
Margrit Schwarz, David W. Russell, John M. Dietschy, Stephen D. Turley   +3 more
doaj   +1 more source

Molecular targets of hypolipidemic action of sesquiterpene lactones [PDF]

, 2018
Experiments on rats with hyperlipidemia model induced by cholesterol-rich diet during 4 weeks showed that the daily treatment with sesquiterpene lactone grossgemin and ludartin in doses 10 mg/kg for a period of 14 days led to decrease ...
Кайдаш, О. А., Пфаргер, Ю. А.   +1 more
core  

Development and Characterisation of a Starvation‐ and Exercise‐Induced Murine Model of Microvesicular Steatosis Relevant to Anorexia Nervosa

Liver International Communications, Volume 7, Issue 1, March 2026.
ABSTRACT Anorexia nervosa (AN) leads to severe dietary restriction, low body weight, and in many patients, hepatocellular steatosis. Clinically, hepatic fat in AN is usually macrovesicular, whereas microvesicular steatosis is more often associated with severe starvation and mitochondrial dysfunction.
Michiko Ishii, Kyoko Hoshikawa, Yuko Takeda, Taketo Nishina, Fumi Uchiyama, Fumiya Suzuki, Keita Maki, Tomohiro Katsumi, Hiroaki Haga, Yoshiyuki Ueno   +9 more
wiley   +1 more source

Mutations in SRD5B1 (AKR1D1), the gene encoding δ 4-3-oxosteroid 5β-reductase, in hepatitis and liver failure in infancy [PDF]

, 2003
Background: A substantial group of patients with cholestatic liver disease in infancy excrete, as the major urinary bile acids, the glycine and taurine conjugates of 7α-hydroxy-3-oxo-4-cholenoic acid and 7α,12α -dihydroxy-3-oxo-4-cholenoic acid.
Bouquet, J. (Jan), Clayton, P. (Peter), Custard, E.J. (E.), Duran, M. (Marinus), Lemonde, H. (Hugh), Overmars, W., Scambler, P.J. (Peter)   +6 more
core   +5 more sources